Zobrazeno 1 - 10
of 226
pro vyhledávání: '"Pascal Mäser"'
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 23, Iss , Pp 44-53 (2023)
Suramin is one of the oldest drugs in use today. It is still the treatment of choice for the hemolymphatic stage of African sleeping sickness caused by Trypanosoma brucei rhodesiense, and it is also used for surra in camels caused by Trypanosoma evan
Externí odkaz:
https://doaj.org/article/3beabf9372d546fc86fc9893d69c7c1e
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Antimalarial resistance to the first-line partner drug piperaquine (PPQ) threatens the effectiveness of artemisinin-based combination therapy. In vitro piperaquine resistance is characterized by incomplete growth inhibition, i.e. increased parasite g
Externí odkaz:
https://doaj.org/article/c86a51b4ecc24b17b0c575f258d5446c
Autor:
Sebastian Walesch, Ronald Garcia, Abdelhalim B. Mahmoud, Fabian Panter, Sophie Bollenbach, Pascal Mäser, Marcel Kaiser, Daniel Krug, Rolf Müller
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 3 (2024)
ABSTRACTIn the past century, microbial natural products have proven themselves to be substantial and fruitful sources of anti-infectives. In addition to the well-studied Actinobacteria, understudied bacterial taxa like the Gram-negative myxobacteria
Externí odkaz:
https://doaj.org/article/b6e3d736a4d74369a8c28d3ceeea480d
Autor:
Lore Baert, Serena Rudy, Mélanie Pellisson, Thierry Doll, Romina Rocchetti, Marcel Kaiser, Pascal Mäser, Matthias Müller
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 1, p e0011559 (2024)
The parasite Leishmania donovani is one of the species causing visceral leishmaniasis in humans, a deadly infection claiming up to 40,000 lives each year. The current drugs for leishmaniasis treatment have severe drawbacks and there is an urgent need
Externí odkaz:
https://doaj.org/article/0559f775e19b434eb173945480fa2e87
Autor:
Nina Vahekeni, Théo Brillatz, Marjan Rahmaty, Monica Cal, Sonja Keller-Maerki, Romina Rocchetti, Marcel Kaiser, Sibylle Sax, Kevin Mattli, Evelyn Wolfram, Laurence Marcourt, Emerson Ferreira Queiroz, Jean-Luc Wolfender, Pascal Mäser
Publikováno v:
Molecules, Vol 29, Iss 7, p 1611 (2024)
Folk medicine is widely used in Angola, even for human African trypanosomiasis (sleeping sickness) in spite of the fact that the reference treatment is available for free. Aiming to validate herbal remedies in use, we selected nine medicinal plants a
Externí odkaz:
https://doaj.org/article/af4925c1057c4951af249559e86d85a1
Publikováno v:
Biology, Vol 13, Iss 3, p 178 (2024)
The present frontrunners in the chemotherapy of infections caused by protozoa are nitro-based prodrugs that are selectively activated by PFOR-mediated redox reactions. This study seeks to analyze the distribution of PFOR in selected protozoa and bact
Externí odkaz:
https://doaj.org/article/e679b6d1bb394d6fb3d0ae4b457cf20a
Autor:
Pascal Mäser, Sonja Bernhard, Reto Brun, Christian Burri, Sébastien Gagneux, Manuel W. Hetzel, Marcel Kaiser, Christian Lengeler, Gerd Pluschke, Elisabeth Reus, Matthias Rottmann, Jürg Utzinger, Louisa Warryn, Sergio Wittlin, Jennifer Keiser
Publikováno v:
CHIMIA, Vol 77, Iss 9 (2023)
Thanks to its expertise in clinical research, epidemiology, infectious diseases, microbiology, parasitology, public health, translational research and tropical medicine, coupled with deeply rooted partnerships with institutions in low- and middle-inc
Externí odkaz:
https://doaj.org/article/0810ed06255e4e4c8ea49405fe36758f
Autor:
Jürg Utzinger, Pascal Mäser
Publikováno v:
CHIMIA, Vol 77, Iss 9 (2023)
The year 2023 marks the 80th anniversary of the Swiss Tropical and Public Health Institute (Swiss TPH). Associated with the University of Basel, Swiss TPH combines research, education and services, working across a value chain from innovation and val
Externí odkaz:
https://doaj.org/article/5448565b4a6f4a3ab5ad8739f03d4d9d
Autor:
Lukas Meier, Marina Antillon, Christian Burri, Nakul Chitnis, Yvette Endriss, Jennifer Keiser, Sarah Moore, Pie Müller, Melissa Penny, Till S. Voss, Pascal Mäser, Jürg Utzinger
Publikováno v:
CHIMIA, Vol 77, Iss 9 (2023)
In pursuing novel therapeutic solutions, drug discovery and development rely on efficiently utilising existing knowledge and resources. Repurposing know-how, a strategy that capitalises on previously acquired information and expertise, has emerged as
Externí odkaz:
https://doaj.org/article/893f70b540d3482ca499ff5f9881f1c1
Autor:
Ozlem Sevik Kilicaslan, Sylvian Cretton, Estelle Hausmann, Luis Quirós-Guerrero, Soumana Karimou, Marcel Kaiser, Pascal Mäser, Philippe Christen, Muriel Cuendet
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
In the course of the screening of plants from Niger for antiprotozoal activity, the methanol extract of Cassia sieberiana, and the dichloromethane extracts of Ziziphus mauritiana and Sesamun alatum were found to be active against protozoan parasites,
Externí odkaz:
https://doaj.org/article/2b110ee577734d31bd6f5c2d4d09b5f3