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pro vyhledávání: '"Pascal Hua"'
Autor:
Balbir Bhogal, Bo Xu, Frank M. Orson, Pascal Hua, Berma M. Kinsey, J. Clifford Waldrep, Vernon Knight, Charles L. Densmore
Publikováno v:
Molecular Therapy. 1(2):180-188
Aerosol delivery of plasmid DNA to the lungs offers the possibility of direct application of gene preparations to pulmonary surfaces as a means of treating a variety of genetic pulmonary disorders. However, the process of jet nebulization rapidly deg
Autor:
Brian Ward, Pascal Hua, Donald E. Bergstrom, Jan Klysik, Berma M. Kinsey, G. Alexander Glass, Frank M. Orson
Publikováno v:
Nucleic acids research. 27(3)
A critical issue for the general application of triple-helix-forming oligonucleotides (TFOs) as modulators of gene expression is the dramatically reduced binding of short TFOs to targets that contain one or two pyrimidines within an otherwise homopur
Publikováno v:
Bioconjugate chemistry. 8(3)
Attachment of 6,9-diamino-2-methoxyacridine to the 5' end of a purine-rich oligodeoxynucleotide targeting a 15 bp oligopurine oligopyrimidine stretch in the promoter region of the interleukin-2 receptor alpha chain (IL-2R alpha) gene results in an ap