Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Pascal Gauduchon"'
Autor:
Anaïs Wambecke, Mohammad Ahmad, Pierre‐Marie Morice, Bernard Lambert, Louis‐Bastien Weiswald, Mégane Vernon, Nicolas Vigneron, Edwige Abeilard, Emilie Brotin, Martin Figeac, Pascal Gauduchon, Laurent Poulain, Christophe Denoyelle, Matthieu Meryet‐Figuiere
Publikováno v:
Molecular Oncology, Vol 15, Iss 12, Pp 3659-3678 (2021)
Ovarian cancer (OC) is the leading cause of death in patients with gynecologic cancers. Due to late diagnosis and resistance to chemotherapy, the 5‐year survival rate in patients with OC is below 40%. We observed that UCA1, a lncRNA previously repo
Externí odkaz:
https://doaj.org/article/8a1e4e42fbc5491cb25a6a66c4690349
Autor:
Matthieu Meryet-Figuiere, Mégane Vernon, Mamy Andrianteranagna, Bernard Lambert, Célia Brochen, Jean-Paul Issartel, Audrey Guttin, Pascal Gauduchon, Emilie Brotin, Florent Dingli, Damarys Loew, Nicolas Vigneron, Anaïs Wambecke, Edwige Abeilard, Emmanuel Barillot, Laurent Poulain, Loredana Martignetti, Christophe Denoyelle
Publikováno v:
Cancers, Vol 13, Iss 16, p 3970 (2021)
The identification of miRNAs’ targets and associated regulatory networks might allow the definition of new strategies using drugs whose association mimics a given miRNA’s effects. Based on this assumption we devised a multi-omics approach to prec
Externí odkaz:
https://doaj.org/article/11e926ab40b840498bae9039620f1c7c
Autor:
Nicolas Vigneron, Matthieu Meryet-Figuière, Audrey Guttin, Jean-Paul Issartel, Bernard Lambert, Mélanie Briand, Marie-Hélène Louis, Mégane Vernon, Pierre Lebailly, Yannick Lecluse, Florence Joly, Sophie Krieger, Stéphanie Lheureux, Bénédicte Clarisse, Alexandra Leconte, Pascal Gauduchon, Laurent Poulain, Christophe Denoyelle
Publikováno v:
Molecular Oncology, Vol 10, Iss 7, Pp 981-992 (2016)
Circulating miRNAs are promising biomarkers in oncology but have not yet been implemented in the clinic given the lack of concordance across studies. In order to increase the cross‐studies reliability, we attempted to reduce and to control the circ
Externí odkaz:
https://doaj.org/article/a12f7c763bef444c973543d6bcaefa4e
Autor:
Christophe Denoyelle, Laurent Poulain, Pascal Gauduchon, Cécile Blanc-Fournier, Marie-Hélène Louis, Florence Giffard, Edwige Abeilard, Anaïs Wambecke, Nicolas Vigneron, Hippolyte Paysant, Louis-Bastien Weiswald, Emilie Brotin, Matthieu Meryet-Figuière, Bernard Lambert, Mégane Vernon
Novel therapeutic strategies are urgently required for the clinical management of chemoresistant ovarian carcinoma, which is the most lethal of the gynecologic malignancies. miRNAs hold promise because they play a critical role in determining the cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e171fe93114453568b49b67d90e86f8
https://doi.org/10.1158/1535-7163.c.6542257
https://doi.org/10.1158/1535-7163.c.6542257
Autor:
Christophe Denoyelle, Pascal Gauduchon, Martin Figeac, Emilie Brotin, Nicolas Vigneron, Louis-Bastien Weiswald, Anaïs Wambecke, Mégane Vernon, Laurent Poulain, Mohammad Ahmad, Matthieu Meryet-Figuière, Edwige Abeilard, Bernard Lambert, Pierre-Marie Morice
Publikováno v:
Molecular Oncology
Molecular Oncology, Vol 15, Iss 12, Pp 3659-3678 (2021)
Molecular Oncology, Vol 15, Iss 12, Pp 3659-3678 (2021)
Ovarian cancer (OC) is the leading cause of death in patients with gynecologic cancers. Due to late diagnosis and resistance to chemotherapy, the 5‐year survival rate in patients with OC is below 40%. We observed that UCA1, a lncRNA previously repo
Autor:
Nicolas Vigneron, Pierre-Marie Morice, Mohammad Ahmad, Pascal Gauduchon, Mégane Vernon, Emilie Brotin, Laurent Poulain, Louis-Bastien Weiswald, Edwige Abeilard, Anaïs Wambecke, Christophe Denoyelle, Matthieu Meryet-Figuière, Bernard Lambert, Martin Figeac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea50e48480c67ced552d53ca01f9ca10
https://doi.org/10.1002/1878-0261.13045/v2/response1
https://doi.org/10.1002/1878-0261.13045/v2/response1
Autor:
Nicolas Vigneron, Mélanie Briand, Bernard Lambert, Laurent Poulain, Stephanie Lheureux, Marie-Hélène Louis, Cécile Blanc-Fournier, Pascal Gauduchon, Mégane Vernon, Florence Joly, Christophe Denoyelle, Sophie Krieger, Matthieu Meryet-Figuière
Publikováno v:
Clinical Chemistry
Clinical Chemistry, American Association for Clinical Chemistry, 2020, ⟨10.1093/clinchem/hvz013⟩
Clinical Chemistry, American Association for Clinical Chemistry, 2020, ⟨10.1093/clinchem/hvz013⟩
Background Identifying patients with high-grade serous ovarian cancer (HGSOC) who will respond to treatment remains a clinical challenge. We focused on miR-622, a miRNA involved in the homologous recombination repair (HRR) pathway, and we assessed it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea4c98fc4e7478387105c97abd87b891
https://hal-normandie-univ.archives-ouvertes.fr/hal-02465285
https://hal-normandie-univ.archives-ouvertes.fr/hal-02465285
Autor:
Mamy Andrianteranagna, Emilie Brotin, Emmanuel Barillot, Mégane Vernon, Edwige Abeilard, Loredana Martignetti, Nicolas Vigneron, Jean-Paul Issartel, Damarys Loew, Célia Brochen, Anaïs Wambecke, Matthieu Meryet-Figuière, Florent Dingli, Pascal Gauduchon, Audrey Guttin, Christophe Denoyelle, Laurent Poulain, Bernard Lambert
Publikováno v:
Cancers, Vol 13, Iss 3970, p 3970 (2021)
Cancers
Volume 13
Issue 16
Cancers
Volume 13
Issue 16
Simple Summary The re-introduction of miRNAs with tumor-suppressor activity in cancer cells has not yet been implemented in clinical practice yet. However, the identification of miRNAs’ targets and associated regulatory networks might allow the def
Autor:
Charlène Duboc, Laurent Poulain, Marie-Hélène Louis, Edwige Abeilard, Marie Villedieu, Christophe Denoyelle, Pascal Gauduchon, Cécile Pétigny-Lechartier, Abdelghani Jebahi
Publikováno v:
Molecular Cancer Therapeutics. 16:102-115
The identification of novel therapeutic strategies is an important urgent requirement for the clinical management of ovarian cancer, which remains the leading cause of death from gynecologic cancer. Several studies have shown that the antiapoptotic p
Autor:
Marie-Laure, Bonnefond, Romane, Florent, Sophie, Lenoir, Bernard, Lambert, Edwige, Abeilard, Florence, Giffard, Marie-Hélène, Louis, Nicolas, Elie, Mélanie, Briand, Denis, Vivien, Laurent, Poulain, Pascal, Gauduchon, Monique, N'Diaye
Publikováno v:
Oncotarget
The anti-apoptotic proteins Bcl-xL and Mcl-1 have been identified to play a pivotal role in apoptosis resistance in ovarian cancer and constitute key targets for innovative therapeutic strategies. Although BH3-mimetics (i.e. ABT-737) potently inhibit