Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Pascal G. Doornebosch"'
Autor:
Eveline E. Vietsch, Diba Latifi, Maaike Verheij, Elise W.A. van der Oost, Roeland F. de Wilde, Roel Haen, Anne Loes van den Boom, Bas Groot Koerkamp, Pascal G. Doornebosch, Victorien M.T. van Verschuer, Ariadne H.A.G. Ooms, Farzana Mohammad, Marcella Willemsen, Joachim G.J.V. Aerts, Ricki T. Krog, Noel F.C.C. de Miranda, Thierry P.P. van den Bosch, Yvonne M. Mueller, Peter D. Katsikis, Casper H.J. van Eijck
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest solid tumors and is resistant to immunotherapy. B cells play an essential role in PDAC progression and immune responses, both locally and systemically. Moreover, increasing evidence
Externí odkaz:
https://doaj.org/article/76e52e62c5914a719b469a7a5bbebb64
Autor:
Yannick S. Rakké, Lucia Campos Carrascosa, Adriaan A. van Beek, Valeska de Ruiter, Rachelle S. van Gemerden, Michail Doukas, Pascal G. Doornebosch, Maarten Vermaas, Susan ter Borg, Erwin van der Harst, Peter Paul L.O. Coene, Mike Kliffen, Dirk J. Grünhagen, Cornelis Verhoef, Jan N.M. IJzermans, Jaap Kwekkeboom, Dave Sprengers
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 1, Pp 77-97 (2023)
Background & Aims: In contrast to mismatch repair deficient colorectal carcinoma (CRC), MMR proficient (pMMR) CRC does not respond to immune checkpoint blockade. We studied immune checkpoint stimulation via glucocorticoid-induced tumor necrosis facto
Externí odkaz:
https://doaj.org/article/4a888c4532714648a65f508089f7a907
Autor:
Nikki S. IJzerman, Wills F. Filipe, Peter de Bruijn, Florian E. Buisman, Leni van Doorn, Pascal G. Doornebosch, Jessica J. Holster, Cecile Grootscholten, Dirk J. Grünhagen, Christian P.E. van Bommel, Marjolein Y.V. Homs, Niels F.M. Kok, Cornelis Verhoef, Bas Groot Koerkamp, Koert F.D. Kuhlmann, Ron H.J. Mathijssen, Stijn L.W. Koolen
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 162, Iss , Pp 114625- (2023)
Background: Floxuridine’s high hepatic extraction ratio and short elimination half-life allows maximum liver exposure with minimal systemic side-effects. This study attempts to quantify the systemic exposure of floxuridine. Methods: Patients underg
Externí odkaz:
https://doaj.org/article/56549eb131c04a128fbca3d683e0aa28
Autor:
Hein Putter, Koos Burggraaf, Alexander L Vahrmeijer, J Sven D Mieog, Alexander L. Vahrmeijer, Ruben P J Meijer, Robin A Faber, Okker D Bijlstra, Jeffrey P B M Braak, Elma Meershoek-Klein Kranenbarg, Denise E Hilling, Ruben P.J. Meijer, Robin A. Faber, Okker D. Bijlstra, Jeffrey P.B.M. Braak, E. Meershoek-Klein Kranenbarg, J Hein Putter, Sven D. Mieog, E Denise, Hilling Tjeerd S. Aukema, I.M Coen, Johanne G. Bloemen, Annelies Bodegom, Fran Boersma, Koop Bosscha, Mark A.M. Brouwers, Esther C.J. Consten, Pascal G. Doornebosch, Dashti Faraj, Paul D. Gobardhan, Fabian .A. Holman, Tessa Kauwenbergh, Andreas W.K.S. Marinelli, Peter A. Neijenhuis, Koen C.M.J. Peeters, Daan J. Sikkenk, Laurents P.S. Stassen, Willem-Hans Steup, Maxime J.M. van der Valk, Bob J. van Wely, Lissa Wullaert
Publikováno v:
BMJ Open, Vol 12, Iss 4 (2022)
Introduction Anastomotic leakage (AL) is one of the major complications after colorectal surgery. Compromised tissue perfusion at the anastomosis site increases the risk of AL. Several cohort studies have shown that indocyanine green (ICG) combined w
Externí odkaz:
https://doaj.org/article/14edae49e0734a728c1124af7464c499
Autor:
Sarah Sharabiany, Robin D. Blok, Oren Lapid, Roel Hompes, Wilhelmus A. Bemelman, Victor P. Alberts, Bas Lamme, Jan H. Wijsman, Jurriaan B. Tuynman, Arend G. J. Aalbers, Geerard L. Beets, Hans F. J. Fabry, Ivan M. Cherepanin, Fatih Polat, Jacobus W. A. Burger, Harm J. T. Rutten, Robert J. I. Bosker, Koen Talsma, Joost Rothbarth, Cees Verhoef, Anthony W. H. van de Ven, Jarmila D. W. van der Bilt, Eelco J. R. de Graaf, Pascal G. Doornebosch, Jeroen W. A. Leijtens, Jeroen Heemskerk, Baljit Singh, Sanjay Chaudhri, Michael F. Gerhards, Tom M. Karsten, Johannes H. W. de Wilt, Andre J. A. Bremers, Ronald J. C. L. M. Vuylsteke, Gijsbert Heuff, Anna A. W. van Geloven, Pieter J. Tanis, Gijsbert D. Musters
Publikováno v:
BMC Surgery, Vol 20, Iss 1, Pp 1-8 (2020)
Abstract Background Abdominoperineal resection (APR) for rectal cancer is associated with high morbidity of the perineal wound, and controversy exists about the optimal closure technique. Primary perineal wound closure is still the standard of care i
Externí odkaz:
https://doaj.org/article/7a81c2987bdc4d19a4ac5c5fbad22529
Autor:
Nik Dekkers, Jurjen J. Boonstra, Leon M. G. Moons, Roel Hompes, Barbara A. Bastiaansen, Jurriaan B. Tuynman, Arjun D. Koch, Bas L. A. M. Weusten, Apollo Pronk, Peter A. Neijenhuis, Marinke Westerterp, Wilbert B. van den Hout, Alexandra M. J. Langers, Jolein van der Kraan, Alaa Alkhalaf, Jonathan Y. L. Lai, Frank ter Borg, Hans Fabry, Eric Halet, Matthijs P. Schwartz, Wouter B. Nagengast, Jan Willem A. Straathof, Rogier W. R. ten Hove, Leendert H. Oterdoom, Christiaan Hoff, Eric J Th Belt, David D. E. Zimmerman, Muhammed Hadithi, Hans Morreau, Erienne M. V. de Cuba, Jeroen W. A. Leijtens, Hans F. A. Vasen, Monique E. van Leerdam, Eelco J. R. de Graaf, Pascal G. Doornebosch, James C. H. Hardwick
Publikováno v:
BMC Gastroenterology, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background In the recent years two innovative approaches have become available for minimally invasive en bloc resections of large non-pedunculated rectal lesions (polyps and early cancers). One is Transanal Minimally Invasive Surgery (TAMIS)
Externí odkaz:
https://doaj.org/article/1ef71de2e92845b3844c7239c32045e7
Autor:
B.J. Noordman, Maria Verseveld, D. Verver, J.H.W. de Wilt, Pascal G. Doornebosch, E. J. R. de Graaf, Cees Verhoef, Sjaak Pouwels, Marloes A. G. Elferink
Publikováno v:
European Journal of Surgical Oncology, 48, 5, pp. 1153-1160
European Journal of Surgical Oncology, 48, 1153-1160
European Journal of Surgical Oncology, 48(5), 1153-1160. W.B. Saunders
European Journal of Surgical Oncology, 48, 1153-1160
European Journal of Surgical Oncology, 48(5), 1153-1160. W.B. Saunders
Introduction Local excision is increasingly used as an alternative treatment for radical surgery in patients with early stage clinical T1 (cT1) rectal cancer. This study provides an overview of incidence, staging accuracy and treatment strategies in
Autor:
Hans Morreau, Tom van Wezel, Rob A.E.M. Tollenaar, Paul H.C. Eilers, Tom Karsten, Jan Oosting, Noel F.C.C. de Miranda, Pascal G. Doornebosch, Eelco J.R. de Graaf, Ronald van Eijk, Esther H. Lips
Purpose: Adequate preoperative staging of large sessile rectal tumors requires identifying adenomas that already contain an invasive focus, specifically those that are growing in or beyond the submucosa. We systematically compared chromosomal instabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44fd67a3b97976165f320a1951c902ed
https://doi.org/10.1158/1078-0432.c.6517314
https://doi.org/10.1158/1078-0432.c.6517314
Autor:
Hans Morreau, Tom van Wezel, Rob A.E.M. Tollenaar, Paul H.C. Eilers, Tom Karsten, Jan Oosting, Noel F.C.C. de Miranda, Pascal G. Doornebosch, Eelco J.R. de Graaf, Ronald van Eijk, Esther H. Lips
Supplementary Table from Progression and Tumor Heterogeneity Analysis in Early Rectal Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5055ec508cace8a41261fd578c240746
https://doi.org/10.1158/1078-0432.22439931
https://doi.org/10.1158/1078-0432.22439931
Autor:
Carlijn I. Buis, Dirk J. Grünhagen, Frederik J H Hoogwater, Niels F.M. Kok, Hwai-Ding Lam, Andries E. Braat, Joost M. Klaase, Cornelis H. C. Dejong, Hendrik A. Marsman, Gijs A. Patijn, Eric T.J. Belt, Jan N. M. IJzermans, N. Tjarda van Heek, Daan J. Lips, Esther C. J. Consten, Wouter W. te Riele, Arthur K.E. Elfrink, Ninos Ayez, Hasan H. Eker, Marieke T. de Boer, Hans Torrenga, Koert F.D. Kuhlmann, Marcel den Dulk, Mike S L Liem, Babs M Zonderhuis, Koop Bosscha, Geert Kazemier, Marc G. Besselink, I. Quintus Molenaar, Cornelis Verhoef, Peter B. van den Boezem, Jeroen Hagendoorn, S. J. Oosterling, Pascal G. Doornebosch, Wouter K. G. Leclercq, Rutger-Jan Swijnenburg
Publikováno v:
HPB, 23(10), 1506-1517. John Wiley & Sons Inc.
HPB, 23(10), 1506-1517. ELSEVIER SCI LTD
Hpb, 23, 1506-1517
Hpb, 23(10), 1506-1517. ELSEVIER SCI LTD
HPB, 23(10), 1506-1517. John Wiley and Sons Inc.
Hpb, 23, 10, pp. 1506-1517
HPB, 23(10), 1506-1517. ELSEVIER SCI LTD
Hpb, 23, 1506-1517
Hpb, 23(10), 1506-1517. ELSEVIER SCI LTD
HPB, 23(10), 1506-1517. John Wiley and Sons Inc.
Hpb, 23, 10, pp. 1506-1517
BACKGROUND: Liver resection is high-risk surgery in particular in elderly patients. The aim of this study was to explore postoperative outcomes after liver resection in elderly patients.METHODS: In this nationwide study, all patients who underwent li