Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Pascal Courtellemont"'
Publikováno v:
Toxicology and Applied Pharmacology. 246:66-73
Several cases of skin sensitization have been reported following the application of thimerosal, which is composed of ethyl mercury and thiosalicylic acid (TSA). However, few in vitro studies have been carried out on human dendritic cells (DCs) which
Autor:
Béatrice Le Varlet, Camille Migdal, Sandra Trompezinski, M. Tailhardat, Pascal Courtellemont, Marek Haftek, Mireille Serres
Publikováno v:
Toxicology and Applied Pharmacology. 230:397-406
Dendritic cells (DCs), efficient-antigen presenting cells play an important role in initiating and regulating immune responses. DC maturation following exposure to nickel or DNCB induced an up-regulation of phenotypic markers and inflammatory cytokin
Autor:
Magalie Cluzel-Tailhardat, Marc Vocanson, Béatrice Levarlet, Magalie Valeyrie, Aurore Rozières, Ana Hennino, Cyril Chavagnac, Gaelle Poyet, Jean-François Nicolas, Pascal Courtellemont
Publikováno v:
Journal of Investigative Dermatology. 128:2119-2122
Autor:
D. Pelle de Queral, Pascal Courtellemont, Marc Vocanson, Robin Kurfurst, Mathilde Bonnet-Duquennoy, Magalie Cluzel-Tailhardat, B. Le Varlet, J.-F. Nicolas
Publikováno v:
Toxicology Letters. 174:98-109
A critical step in the induction of allergic contact dermatitis is the interaction of haptens with immature dendritic cells (iDC) leading to their activation. Therefore iDC appear as suitable targets for the evaluation of the sensitizing properties o
Autor:
Catherine Dalbiez-Gauthier, D. Schmitt, B. Le Varlet, Pascal Courtellemont, J. Peguet-Navarro
Publikováno v:
Toxicology in Vitro. 18:359-364
In a previous study, we have used UVB-irradiated human skin explants and the allostimulatory function of Langerhans cells (LC) to determine immune protection factors (IPF) for sunscreens. We sought here to simplify the model by using either human enr
Publikováno v:
Archives of Dermatological Research. 292:306-311
The present study was aimed at determining immune protection factors (IPFs) for sunscreens. Human skin explants from donors of phototype II-III were treated, or not, with sunscreens with increasing sun protection factors (SPF 4, 8, 15 and 30), or the
Autor:
Gerard Redziniak, Pascal Courtellemont, Daniel Schmitt, J. Peguet-Navarro, Frédérique-Marie Rattis
Publikováno v:
Photochemistry and Photobiology. 62:914-916
Urocanic acid (UCA) represents the major ultraviolet B (UVB, 290-320 nm)-absorbing component of the skin. Trans-UCA is naturally produced in the stratum corneum and converts to the cis isomer upon UVB irradiation. In this study, we examined the effec
Autor:
Marie-Jeanne Staquet, Daniel Schmitt, Colette Dezutter-Dambuyant, J. Peguet-Navarro, Frédérique-Marie Rattis, Pascal Courtellemont, Gerard Redziniak
Publikováno v:
European Journal of Immunology. 26:449-453
In addition to T cell receptor triggering, activation of T cells requires co-stimulatory signals that have been shown to be mainly initiated through CD28. We analyzed the expression and function of the two ligands for CD28, B7-1 (CD80) and B7-2 (CD86
Autor:
Mireille Serres, Marek Haftek, M. Tailhardat, Pascal Courtellemont, Lucie Foggia, Camille Migdal
Publikováno v:
Toxicology. 274(1-3)
Thimerosal, a mercury derivative composed of ethyl mercury chloride (EtHgCl) and thiosalicylic acid (TSA), is widely used as a preservative in vaccines and cosmetic products and causes cutaneous reactions. Since dendritic cells (DCs) play an essentia