Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Pascal Bouvain"'
Autor:
Zheheng Ding, Xueqing Liu, Hongyan Jiang, Jianfeng Zhao, Sebastian Temme, Pascal Bouvain, Christina Alter, Puyan Rafii, Jürgen Scheller, Ulrich Flögel, Hongtao Zhu, Zhaoping Ding
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Histological analysis with 2,3,5-triphenyltetrazolium chloride (TTC) staining is the most frequently used tool to detect myocardial ischemia/reperfusion injury. However, its practicality is often challenged by poor image quality in gross his
Externí odkaz:
https://doaj.org/article/92fb827015d244dcb175ccb140c693d9
Autor:
Timo Massold, Fady Ibrahim, Viola Niemann, Bodo Steckel, Katrin Becker, Jürgen Schrader, Johannes Stegbauer, Sebastian Temme, Maria Grandoch, Ulrich Flögel, Pascal Bouvain
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Vascular inflammation plays a key role in the development of aortic diseases. A potential novel target for treatment might be CD73, an ecto-5′-nucleotidase that generates anti-inflammatory adenosine in the extracellular space. Here, we inv
Externí odkaz:
https://doaj.org/article/275be7bceaad46c48123f7ca0ed2f78a
Autor:
Olga Koshkina, Timo Rheinberger, Vera Flocke, Anton Windfelder, Pascal Bouvain, Naomi M. Hamelmann, Jos M. J. Paulusse, Hubert Gojzewski, Ulrich Flögel, Frederik R. Wurm
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-8 (2023)
Abstract In vivo monitoring of polymers is crucial for drug delivery and tissue regeneration. Magnetic resonance imaging (MRI) is a whole-body imaging technique, and heteronuclear MRI allows quantitative imaging. However, MRI agents can result in env
Externí odkaz:
https://doaj.org/article/b75f7cdd54b44b0f9a06bafc9275d94e
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundInflammation and metabolism exhibit a complex interplay, where inflammation influences metabolic pathways, and in turn, metabolism shapes the quality of immune responses. Here, glucose turnover is of special interest, as proinflammatory imm
Externí odkaz:
https://doaj.org/article/cc0864acdbfa42428eaa7d7e9c29886a
Autor:
Tamara Straub, Julia Nave, Pascal Bouvain, Mohammad Akbarzadeh, Siva Sai Krishna Dasa, Julia Kistner, Zhaoping Ding, Aseel Marzoq, Stefanie Stepanow, Katrin Becker, Julia Hesse, Karl Köhrer, Ulrich Flögel, Mohammad R. Ahmadian, Brent A. French, Jürgen Schrader, Sebastian Temme
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract After myocardial infarction (MI), epicardial cells reactivate their embryonic program, proliferate and migrate into the damaged tissue to differentiate into fibroblasts, endothelial cells and, if adequately stimulated, to cardiomyocytes. Tar
Externí odkaz:
https://doaj.org/article/926c75b0bc764b2880ee83245f14ba59
Autor:
Sebastian Temme, Mina Yakoub, Pascal Bouvain, Guang Yang, Jürgen Schrader, Johannes Stegbauer, Ulrich Flögel
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
The pathophysiology of the initiation and progression of abdominal aortic aneurysms (AAAs) and aortic dissections (AADs) is still unclear. However, there is strong evidence that monocytes and macrophages are of crucial importance in these processes.
Externí odkaz:
https://doaj.org/article/a2d5f614f9f14f88af43099fdfd32f90
Autor:
Pascal Bouvain, Zhaoping Ding, Shiwa Kadir, Patricia Kleimann, Nils Kluge, Zeynep-Büsra Tiren, Bodo Steckel, Vera Flocke, Ria Zalfen, Patrick Petzsch, Thorsten Wachtmeister, Gordon John, Nirojah Subramaniam, Wolfgang Krämer, Tobias Strasdeit, Mehrnaz Mehrabipour, Jens M. Moll, Rolf Schubert, Mohammad Reza Ahmadian, Florian Bönner, Udo Boeken, Ralf Westenfeld, Daniel Robert Engel, Malte Kelm, Jürgen Schrader, Karl Köhrer, Maria Grandoch, Sebastian Temme, Ulrich Flögel
Publikováno v:
Nature Cardiovascular Research. 2:126-143
Neutrophils play a complex role during onset of tissue injury and subsequent resolution and healing. To assess neutrophil dynamics upon cardiovascular injury, here we develop a non-invasive, background-free approach for specific mapping of neutrophil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc7a7677d67abfd778d1f544e171e19c
https://doi.org/10.1038/s44161-022-00210-w
https://doi.org/10.1038/s44161-022-00210-w
Autor:
Zhaoping, Ding, Kezhe, Tan, Christina, Alter, Sebastian, Temme, Pascal, Bouvain, Christoph, Owenier, Sebastian, Hänsch, Sebastian, Wesselborg, Christoph, Peter, Stefanie, Weidtkamp-Peters, Ulrich, Flögel, Jessica, Schira-Heinen, Kai, Stühler, Julia, Hesse, Gesine, Kögler, Jürgen, Schrader
Publikováno v:
Journal of Molecular and Cellular Cardiology. 175:29-43
Regenerating the injured heart remains one of the most vexing challenges in cardiovascular medicine. Cell therapy has shown potential for treatment of myocardial infarction, but low cell retention so far has limited its success. Here we show that int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::914b8948ee2727a522e0a12d53228c76
https://doi.org/10.1016/j.yjmcc.2022.11.006
https://doi.org/10.1016/j.yjmcc.2022.11.006
Autor:
Olga Koshkina, Timo Rheinberger, Vera Flocke, Anton Windfelder, Pascal Bouvain, Naomi M. Hamelmann, Jos M.J. Paulusse, Hubert Hubert Gojzewski, Ulrich Flögel, Frederik Wurm
Imaging and tracing materials inside the body is essential to develop functional materials for personalized therapies, including drug delivering nanocarriers and artificial tissues. Magnetic Resonance Imaging (MRI) is a key whole-body imaging technol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7716d6f3d17448f4b103ae2cbdacd27
https://doi.org/10.26434/chemrxiv-2022-nxhd6
https://doi.org/10.26434/chemrxiv-2022-nxhd6
Autor:
Christoph Grapentin, Pascal Bouvain, Sebastian Temme, Ulrich Flögel, Wolfgang Krämer, Rolf Schubert
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 142:114-122
Background Perfluorocarbon (PFC)-nanoemulsions (NE) are a convenient tool for 19F magnetic resonance imaging in cell and animal experiments. Typical preparation methods, like high-pressure homogenization or microfluidization, produce nanoemulsions in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2850f1f977f34071eaa49751a021abfc
https://doi.org/10.1016/j.ejpb.2019.06.014
https://doi.org/10.1016/j.ejpb.2019.06.014