Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Pascal Billot"'
Publikováno v:
Chemical Engineering Science. 128:36-43
Many active pharmaceutical ingredients (APIs) are poorly soluble and therefore poorly bioavailable. Advances in crystal engineering have motivated research into the design of pharmaceutical co-crystals. This study examines the formation of agomelatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2598a78d7749b2988cebcbd6f83a8eb
https://doi.org/10.1016/j.ces.2015.01.045
https://doi.org/10.1016/j.ces.2015.01.045
Publikováno v:
Organic Process Research & Development. 17:505-511
Cocrystallization as a purification step was the only way to isolate an active pharmaceutical ingredient with acceptable chemical and physical specifications. The process design controlling chemical quality and polymorphism issues is described, from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1387fa4a3f00550d86e2dc60404abcd
https://doi.org/10.1021/op300214p
https://doi.org/10.1021/op300214p
Publikováno v:
Organic Process Research & Development. 14:511-523
In the pharmaceutical industry, controlling the crystallization process of active pharmaceutical ingredients (API) is crucial to ensure chemical quality and physical properties. Process analytical technologies (PAT) provide a large number of tools th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12a52017ea8426d9147a9665a035249e
https://doi.org/10.1021/op900281m
https://doi.org/10.1021/op900281m
Publikováno v:
International Journal of Pharmaceutics. 374:82-89
In this paper, a new approach to model cocrystal phase diagrams is presented. Starting from an initial set of data, the phase diagram is obtained from discontinuous isoperibolic thermal analysis (DITA) and basic thermodynamic data (enthalpies and sol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2383b2c384597cc2666572f6a0a9c3a
https://doi.org/10.1016/j.ijpharm.2009.03.016
https://doi.org/10.1016/j.ijpharm.2009.03.016
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 63
Many active pharmaceutical ingredients (APIs) are poorly soluble and therefore poorly bioavailable. In recent years, the advances in crystal engineering have motivated the research in the design of pharmaceutical co-crystals. This study examines the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce4c9a83a8f396973bea01f2318ad6c1
https://pubmed.ncbi.nlm.nih.gov/24995701
https://pubmed.ncbi.nlm.nih.gov/24995701
Autor:
Bruno Pitard, Pascal Billot
Publikováno v:
Journal of Chromatography A. 623:305-313
Taguchi design experiments were conducted in order to identify and optimize the parameters that yield a maximum separation of 26 solvents commonly found in bulk pharmaceuticals. Wide-bore columns with chemically cross-linked stationary phases of diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8a0aa4720934cca74a5b012eb11591a
https://doi.org/10.1016/0021-9673(92)80370-a
https://doi.org/10.1016/0021-9673(92)80370-a
Publikováno v:
Crystal Growth & Design
Crystal Growth & Design, American Chemical Society, 2004, 4 (5), pp.965-969. ⟨10.1021/cg030046e⟩
Crystal Growth & Design, 2004, 4 (5), pp.965-969. ⟨10.1021/cg030046e⟩
Crystal Growth & Design, American Chemical Society, 2004, 4 (5), pp.965-969. ⟨10.1021/cg030046e⟩
Crystal Growth & Design, 2004, 4 (5), pp.965-969. ⟨10.1021/cg030046e⟩
Hollow and solid whiskers are formed during the solvent exchange from the dimethyl sulfoxide or dimethylformamide solvates of dexamethasone acetate to the sesquihydrate by immersion of the initial phase in water. Detailed investigations using mainly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7482801c0fcb31b5514908d40236af36
https://hal-normandie-univ.archives-ouvertes.fr/hal-01935919
https://hal-normandie-univ.archives-ouvertes.fr/hal-01935919
Publikováno v:
Die Makromolekulare Chemie. 177:1889-1893
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8fc2aabd4ecffc50ff4252f95f86b4f
https://doi.org/10.1002/macp.1976.021770619
https://doi.org/10.1002/macp.1976.021770619
Publikováno v:
Die Makromolekulare Chemie. 178:1641-1650
AB block copolymers with a polyvinyl block (polystyrene or polybutadiene) and a polypeptide block (poly(carbobenzoxy-L-lysine)) were prepared by the following method: at first the polyvinyl block was synthesized by anionic polymerization, then its li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::740c446656f532737324b09df5fa8f81
https://doi.org/10.1002/macp.1977.021780604
https://doi.org/10.1002/macp.1977.021780604