Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Pascal Bielefeld"'
Autor:
Amber Penning, Giorgia Tosoni, Oihane Abiega, Pascal Bielefeld, Caterina Gasperini, Davide De Pietri Tonelli, Carlos P. Fitzsimons, Evgenia Salta
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2022)
The adult neurogenic niches are complex multicellular systems, receiving regulatory input from a multitude of intracellular, juxtacrine, and paracrine signals and biological pathways. Within the niches, adult neural stem cells (aNSCs) generate astroc
Externí odkaz:
https://doaj.org/article/66b59016ce8946bf8754d3b672b30bef
Autor:
Pascal Bielefeld, Marijn Schouten, Guido M. Meijer, Marit J. Breuk, Karlijne Geijtenbeek, Sedef Karayel, Alisa Tiaglik, Anna H. Vuuregge, Ruth A.L. Willems, Diede Witkamp, Paul J. Lucassen, Juan M. Encinas, Carlos P. Fitzsimons
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Convulsive seizures promote adult hippocampal neurogenesis (AHN) through a transient activation of neural stem/progenitor cells (NSPCs) in the subgranular zone (SGZ) of the dentate gyrus (DG). However, in a significant population of epilepsy patients
Externí odkaz:
https://doaj.org/article/1bea6e11e773429e90418b518649ae07
Autor:
Fredrik Berglind, Marco Ledri, Andreas Toft Sørensen, Litsa Nikitidou, Miriam Melis, Pascal Bielefeld, Deniz Kirik, Karl Deisseroth, My Andersson, Merab Kokaia
Publikováno v:
Neurobiology of Disease, Vol 65, Iss , Pp 133-141 (2014)
Synchronized activity is common during various physiological operations but can culminate in seizures and consequently in epilepsy in pathological hyperexcitable conditions in the brain. Many types of seizures are not possible to control and impose s
Externí odkaz:
https://doaj.org/article/3e8d81b144a640f789dab9c832dde6d7
Autor:
Caterina Gasperini, Kiril Tuntevski, Silvia Beatini, Roberta Pelizzoli, Amanda Lo Van, Damiano Mangoni, Rosa M Cossu, Giovanni Pascarella, Paolo Bianchini, Pascal Bielefeld, Margherita Scarpato, Meritxell Pons‐Espinal, Remo Sanges, Alberto Diaspro, Carlos P Fitzsimons, Piero Carninci, Stefano Gustincich, Davide De Pietri Tonelli
Publikováno v:
EMBO Reports, 24(2):e53801. Wiley-Blackwell
Adult neural progenitor cells (aNPCs) ensure lifelong neurogenesis in the mammalian hippocampus. Proper regulation of aNPC fate has thus important implications for brain plasticity and healthy aging. Piwi proteins and the small noncoding RNAs interac
Autor:
Carly E. Whyte, Kailash Singh, Oliver T. Burton, Meryem Aloulou, Lubna Kouser, Rafael Valente Veiga, Amy Dashwood, Hanneke Okkenhaug, Samira Benadda, Alena Moudra, Orian Bricard, Stephanie Lienart, Pascal Bielefeld, Carlos P. Roca, Francisco José Naranjo-Galindo, Félix Lombard-Vadnais, Steffie Junius, David Bending, Masahiro Ono, Tino Hochepied, Timotheus Y.F. Halim, Susan Schlenner, Sylvie Lesage, James Dooley, Adrian Liston
Publikováno v:
Journal of Experimental Medicine. 219
Autor:
Carly E. Whyte, Kailash Singh, Oliver T. Burton, Meryem Aloulou, Lubna Kouser, Rafael Valente Veiga, Amy Dashwood, Hanneke Okkenhaug, Samira Benadda, Alena Moudra, Orian Bricard, Stephanie Lienart, Pascal Bielefeld, Carlos P. Roca, Francisco José Naranjo-Galindo, Félix Lombard-Vadnais, Steffie Junius, David Bending, Masahiro Ono, Tino Hochepied, Timotheus Y.F. Halim, Susan Schlenner, Sylvie Lesage, James Dooley, Adrian Liston
Publikováno v:
JOURNAL OF EXPERIMENTAL MEDICINE
Funder: Fondation pour l'Aide à la Recherche sur la Sclérose en Plaques
Funder: Alzheimer's Association
Funder: European Research Council
Funder: Fondation pour l’Aide à la Recherche sur la Sclérose en Plaques
Funder: Vetens
Funder: Alzheimer's Association
Funder: European Research Council
Funder: Fondation pour l’Aide à la Recherche sur la Sclérose en Plaques
Funder: Vetens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff38c09def949c44dafdb80179d4c709
https://doi.org/10.1084/jem.20212391
https://doi.org/10.1084/jem.20212391
Autor:
Lidia Yshii, Emanuela Pasciuto, Pascal Bielefeld, Loriana Mascali, Pierre Lemaitre, Marika Marino, James Dooley, Lubna Kouser, Stijn Verschoren, Vasiliki Lagou, Hannelore Kemps, Pascal Gervois, Antina de Boer, Oliver T. Burton, Jérôme Wahis, Jens Verhaert, Samar H. K. Tareen, Carlos P. Roca, Kailash Singh, Carly E. Whyte, Axelle Kerstens, Zsuzsanna Callaerts-Vegh, Suresh Poovathingal, Teresa Prezzemolo, Keimpe Wierda, Amy Dashwood, Junhua Xie, Elien Van Wonterghem, Eline Creemers, Meryem Aloulou, Willy Gsell, Oihane Abiega, Sebastian Munck, Roosmarijn E. Vandenbroucke, Annelies Bronckaers, Robin Lemmens, Bart De Strooper, Ludo Van Den Bosch, Uwe Himmelreich, Carlos P. Fitzsimons, Matthew G. Holt, Adrian Liston
Publikováno v:
Nature Immunology
Nature Immunology, 2022, 23 (6), pp.878-891. ⟨10.1038/s41590-022-01208-z⟩
Nature Immunology, 23(6), 878-891. Nature Publishing Group
NATURE IMMUNOLOGY
Nature Immunology, 2022, 23 (6), pp.878-891. ⟨10.1038/s41590-022-01208-z⟩
Nature Immunology, 23(6), 878-891. Nature Publishing Group
NATURE IMMUNOLOGY
The ability of immune-modulating biologics to prevent and reverse pathology has transformed recent clinical practice. Full utility in the neuroinflammation space, however, requires identification of both effective targets for local immune modulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ab80cea5714e906bd81ffe84b531cc
https://lirias.kuleuven.be/handle/20.500.12942/696232
https://lirias.kuleuven.be/handle/20.500.12942/696232
Autor:
Paul J. Lucassen, Aniko Korosi, Anna R. Davidson, Carlos P. Fitzsimons, Maralinde R. Abbink, Pascal Bielefeld, Oihane Abiega, Niels Reijner
Publikováno v:
Stress-the International Journal on the Biology of Stress, 24(2), 189-195. Informa Healthcare
Stress is a potent environmental factor that can confer potent and enduring effects on brain structure and function. Exposure to stress during early life (ELS) has been linked to a wide range of consequences later in life. In particular, ELS exerts l
Autor:
Harm J. Krugers, Niek Brosens, Nathalie Immerzeel, Sylvie L. Lesuis, Rolinka J. van der Loo, Miodrag Mitrić, Paul J. Lucassen, Michel C. van den Oever, Pascal Bielefeld, Steven A. Kushner, Carlos P. Fitzsimons
Publikováno v:
Lesuis, S L, Brosens, N, Immerzeel, N, van der Loo, R J, Mitrić, M, Bielefeld, P, Fitzsimons, C P, Lucassen, P J, Kushner, S A, van den Oever, M C & Krugers, H J 2021, ' Glucocorticoids Promote Fear Generalization by Increasing the Size of a Dentate Gyrus Engram Cell Population ', Biological Psychiatry, vol. 90, no. 7, pp. 494-504 . https://doi.org/10.1016/j.biopsych.2021.04.010, https://doi.org/10.1016/j.biopsych.2021.04.010
Biological Psychiatry, 90(7), 494-504. Elsevier Inc.
Biological Psychiatry, 90(7), 494-504. Elsevier
Biological Psychiatry, 90(7), 494-504. Elsevier USA
Biological Psychiatry, 90(7), 494-504. Elsevier Inc.
Biological Psychiatry, 90(7), 494-504. Elsevier
Biological Psychiatry, 90(7), 494-504. Elsevier USA
BACKGROUND: Traumatic experiences, such as conditioned threat, are coded as enduring memories that are frequently subject to generalization, which is characterized by (re-) expression of fear in safe environments. However, the neurobiological mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::983c04fa3ddc145da89ed28634f88143
https://research.vu.nl/en/publications/0adccf79-cfa2-46b3-b426-3b5f28761f98
https://research.vu.nl/en/publications/0adccf79-cfa2-46b3-b426-3b5f28761f98
Autor:
Carlos P. Fitzsimons, Davide De Pietri Tonelli, P. P. Carninci, Meritxell Pons-Espinal, Stefano Gustincich, C. Gasperini, Paolo Bianchini, K. Tuntevski, Giovanni Pascarella, Pascal Bielefeld, Damiano Mangoni, A. Lo Van, R. M. Cossu, Alberto Diaspro, R. Sanges, Margherita Scarpato, Roberta Pelizzoli
SummaryAdult Neural progenitor cells (aNPCs) ensure lifelong neurogenesis in the mammalian hippocampus. Proper regulation of aNPC fate entails important implications for brain plasticity and healthy aging. Piwi proteins and the small noncoding RNAs i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af91ac13d9bcc11001d84c748f94712f
https://doi.org/10.1101/2020.09.15.297739
https://doi.org/10.1101/2020.09.15.297739