Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Pascal Azar"'
Autor:
Luís Miguel Cardoso Dos Santos, Pascal Azar, Cécile Brun, Stéphane König, Angela Roatti, Alex J. Baertschi, Chiraz Chaabane, Marie-Luce Bochaton-Piallat
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract During atherosclerotic plaque formation, smooth muscle cells (SMCs) switch from a contractile/differentiated to a synthetic/dedifferentiated phenotype. We previously isolated differentiated spindle-shaped (S) and dedifferentiated rhomboid (R
Externí odkaz:
https://doaj.org/article/fcbd53799a9543e1a1afb7cefdd58195
Autor:
Luís Miguel Cardoso Dos Santos, Pascal Azar, Cécile Brun, Stéphane König, Angela Roatti, Alex J Baertschi, Chiraz Chaabane, Marie-Luce Bochaton-Piallat
Background. During atherosclerotic plaque formation smooth muscle cells (SMCs) switch from a contractile/differentiated to a synthetic/dedifferentiated phenotype We previously isolated differentiated spindle-shaped (S) and dedifferentiated rhomboid (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23b95e14063a34219f8bc5cc3824a05b
https://doi.org/10.21203/rs.3.rs-1977590/v1
https://doi.org/10.21203/rs.3.rs-1977590/v1
HIV-1 infection enhances innate function andiTLR7/iexpression in female plasmacytoid dendritic cells
Publikováno v:
Life science alliance. 5(10)
Plasmacytoid dendritic cells (pDCs) express TLR7, a ssRNA-sensor encoded on the X chromosome, which escapes X chromosome inactivation (XCI) in females. pDCs are specialized in the production of type 1 interferons (IFN-I) through TLR7 activation which
Plasmacytoid dendritic cells (pDCs) express TLR7, a ssRNA-sensor encoded on the X chromosome, which escapes X chromosome inactivation (XCI) in females. pDCs are specialized in the production of type 1 interferons (IFN-I) through TLR7 activation which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39838ba6e19ff95f0cad31edb783cb3e
https://doi.org/10.1101/2022.03.14.22272210
https://doi.org/10.1101/2022.03.14.22272210
Autor:
Jean-Charles Guéry, Jacques Izopet, Asma Essat, Arnoo Shaiykova, Caroline Passaes, Sophie Laffont, Ali Youness, Pascal Azar, Michaela Müller-Trutwin, José E. Mejía, Pierre Delobel, Laurence Meyer, Claire Cenac
Publikováno v:
JCI Insight
JCI Insight, American Society for Clinical Investigation, 2020, 5 (12), ⟨10.1172/jci.insight.136047⟩
JCI Insight, American Society for Clinical Investigation, 2020, 5 (12), pp.e136047. ⟨10.1172/jci.insight.136047⟩
JCI Insight, 2020, 5 (12), pp.e136047. ⟨10.1172/jci.insight.136047⟩
JCI Insight, American Society for Clinical Investigation, 2020, 5 (12), ⟨10.1172/jci.insight.136047⟩
JCI Insight, American Society for Clinical Investigation, 2020, 5 (12), pp.e136047. ⟨10.1172/jci.insight.136047⟩
JCI Insight, 2020, 5 (12), pp.e136047. ⟨10.1172/jci.insight.136047⟩
International audience; Type I IFN (IFN-I) production by plasmacytoid DCs (pDCs) occurs during acute HIV-1 infection in response to TLR7 stimulation, but the role of pDC-derived IFN-I in controlling or promoting HIV-1 infection is ambiguous. We repor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e8932b542dcf842ba7049a0070c46a9
https://hal.archives-ouvertes.fr/hal-03012855
https://hal.archives-ouvertes.fr/hal-03012855
Autor:
Solange Grunenwald, Jean-Charles Guéry, Astrid Canivet, Pascal Azar, Julie Chaumeil, Claire Cenac, José E. Mejía, Catherine Pienkowski, Danièle Daviaud, Mélanie Souyris
Publikováno v:
Science Immunology. 3
Toll-like receptor 7 (TLR7) is critical to the induction of antiviral immunity, but TLR7 dosage is also a key pathogenic factor in systemic lupus erythematosus (SLE), an autoimmune disease with strong female bias. SLE prevalence is also elevated in i
Autor:
Nelly Rouquié, Jean-Charles Guéry, Sophie Laffont, Caroline Aspord, Joel Plumas, Pascal Azar, Cyril Seillet
Publikováno v:
The Journal of Immunology. 193:5444-5452
Human plasmacytoid dendritic cells (pDCs) play a major role in innate immunity through the production of type I IFNs after TLR engagement by pathogens. Sex-based differences in the innate function of human pDCs have been established, with pDCs from w