Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Pascal, van der Wegen"'
Autor:
Stefano Castellani, Pieter S. Hiemstra, Anna Diana, Pascal van der Wegen, Francesca Tilesi, Guelnihal Yueksekdag, Joseph Rosenecker, Jamil Aarbiou, Bob J. Scholte, Ruvalic M. Buijs-Offerman, Elena Copreni, Fiorentina Ascenzioni, Piera Assunta Fradiani, Annalucia Carbone, Massimo Conese
Publikováno v:
The Journal of Gene Medicine. 14:733-745
BACKGROUND Epithelial sodium channel (ENaC) hyperactivity has been implicated in the pathogenesis of cystic fibrosis (CF) by dysregulation of fluid and electrolytes in the airways. In the present study, we show proof-of-principle for ENaC inhibition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::517e8563249a6a0513fef251d40d1a4c
https://doi.org/10.1002/jgm.2672
https://doi.org/10.1002/jgm.2672
Autor:
Edwin H. Jacobs, Pascal van der Wegen, Fatima S. F. Aerts Kaya, Bob J. Scholte, Merel Stok, Trudi P. Visser, Ans T. van der Ploeg, Bart N. Lambrecht, Dirk J. Duncker, Arnold J. J. Reuser, Gerard Wagemaker, Monique Willart, Elnaz Farahbakhshian, Monique C. de Waard, Niek P. van Til, Marian A. Kroos, Monique M A Verstegen
Publikováno v:
Blood, 115(26), 5329-5337. American Society of Hematology
Pompe disease (acid α-glucosidase deficiency) is a lysosomal glycogen storage disorder characterized in its most severe early-onset form by rapidly progressive muscle weakness and mortality within the first year of life due to cardiac and respirator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c24f6d34f10c00552fc1c0ecec569ecb
https://doi.org/10.1182/blood-2009-11-252874
https://doi.org/10.1182/blood-2009-11-252874
Autor:
Jamil, Aarbiou, Elena, Copreni, Ruvalic M, Buijs-Offerman, Pascal, van der Wegen, Stefano, Castellani, Annalucia, Carbone, Francesca, Tilesi, Piera, Fradiani, Pieter S, Hiemstra, Guelnihal, Yueksekdag, Anna, Diana, Joseph, Rosenecker, Fiorentina, Ascenzioni, Massimo, Conese, Bob J, Scholte
Publikováno v:
The journal of gene medicine. 14(12)
Epithelial sodium channel (ENaC) hyperactivity has been implicated in the pathogenesis of cystic fibrosis (CF) by dysregulation of fluid and electrolytes in the airways. In the present study, we show proof-of-principle for ENaC inhibition by lentivir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cdcace9c4a7663bd92868c0e48aa4c87
https://pubmed.ncbi.nlm.nih.gov/23074129
https://pubmed.ncbi.nlm.nih.gov/23074129
Autor:
Scot D, Henry, Pascal, van der Wegen, Herold J, Metselaar, Bob J, Scholte, Hugo W, Tilanus, Luc J W, van der Laan
Publikováno v:
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 14(12)
Isolated liver perfusion offers a unique prospect for safe, effective targeting of gene therapies that can be directed against allograft rejection or recurrent diseases such as reinfection by hepatitis C virus (HCV). We aimed to examine the effect of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ae8c64d233b6a1187913de5243a38b13
https://pubmed.ncbi.nlm.nih.gov/19025921
https://pubmed.ncbi.nlm.nih.gov/19025921
Autor:
A. M. Ali Imam, Rogier Louwen, Ruvalic M. Buijs-Offerman, Bob J. Scholte, Frank Grosveld, Pascal van der Wegen, Maarten Sinaasappel
Publikováno v:
Molecular Therapy, 12(2), 374-381. Cell Press
Molecular Therapy, 13(2), 374-381. Cell Press
Molecular Therapy, 13(2), 374-381. Cell Press
Treatment of congenital and acquired liver disease is one of the main issues in the field of gene therapy. Self-inactivating lentiviral vectors have several potential advantages over alternative systems. We have constructed a self-inactivating lentiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87ff1658e4b22b9b57f478f4c15a3e79
https://pure.eur.nl/en/publications/29f5f8a9-590a-42b4-ab5d-9ba0550a3138
https://pure.eur.nl/en/publications/29f5f8a9-590a-42b4-ab5d-9ba0550a3138
Autor:
Bob J. Scholte, Hugo W. Tilanus, Luc J. W. van der Laan, Herold J. Metselaar, Pascal van der Wegen, Scot D. Henry
Publikováno v:
Molecular Therapy, 14(4), 485-493. Cell Press
Chronic hepatitis C virus (HCV) infection has a major medical impact and current treatments are often unsuccessful. RNA interference represents a promising new approach to tackling this problem. The current study details the design and testing of sel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::624487d3a9b2072df9fdacf85f5f8c63
https://pubmed.ncbi.nlm.nih.gov/16872906
https://pubmed.ncbi.nlm.nih.gov/16872906