Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Pascal, Merchiers"'
Autor:
Bart Neyns, Damya Laoui, Julia Katharina Schwarze, Helena Van Damme, Bruno Dombrecht, Máté Kiss, Heleen Roose, Eva Van Overmeire, Daliya Kancheva, Liesbet Martens, Aleksandar Murgaski, Pauline Madeleine Rachel Bardet, Gillian Blancke, Maude Jans, Evangelia Bolli, Maria Solange Martins, Yvon Elkrim, Kiavash Movahedi, Niels Vandamme, Sebahat Ocak, Isabelle Scheyltjens, Lars Vereecke, Frank Aboubakar Nana, Pascal Merchiers, Jo Agnes Van Ginderachter
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 2 (2021)
Background Modulation and depletion strategies of regulatory T cells (Tregs) constitute valid approaches in antitumor immunotherapy but suffer from severe adverse effects due to their lack of selectivity for the tumor-infiltrating (ti-)Treg populatio
Externí odkaz:
https://doaj.org/article/f3b73327b159432399d5c58c01682dd6
Autor:
Johannes Sam, Dafne Franz Demane, Estelle Marrer-Berger, Mariana Werner Sunderland, Christophe Boetsch, Dimitrios Zervas, Anne Goubier, Jake Y. Henry, Teresa Marafioti, Chen Qing, Jan Eckmann, Frederick Arce Vargas, Reto Flury, Sara Belli, Hans Koll, Ayse Akarca, Maria Amann, Bjoern Jacobsen, Lea Leibrock, Anna Śledzińska, Roger Sutmuller, Sergio A. Quezada, Josephine Salimu, Joerg Benz, Claudio Murgia, Isabelle Solomon, Joanne Ruth Clancy, Mark Adrian Brown, Karl S. Peggs, Pascal Merchiers, Ehsan Ghorani, Andrew Georgiou
Publikováno v:
Nature Cancer. 1:1153-1166
Intratumoral regulatory T (Treg) cell abundance associates with diminished antitumor immunity and poor prognosis in human cancers. Recent work demonstrates that CD25, the high-affinity receptor subunit for interleukin (IL)-2, is a selective target fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c86e7b1e8eb4c4edbef7ab01a2f5de0
https://doi.org/10.1038/s43018-020-00133-0
https://doi.org/10.1038/s43018-020-00133-0
Autor:
Yichao Hua, Gerlanda Vella, Florian Rambow, Elizabeth Allen, Asier Antoranz Martinez, Marie Duhamel, Steffie Junius, Ann Smeets, David Nittner, Damya Laoui, Stefanie Dimmeler, Thomas Hehlgans, Adrian Liston, Guiseppe Floris, Diether Lambrechts, Pascal Merchiers, Francesca Maria Bosisio, Jean-Christophe Marine, Susan Schlenner, Gabriele Bergers
SummaryThe lack of T-cell infiltrates is a major obstacle to effective immunotherapy in cancer. Conversely, the formation of tumor-associated tertiary-lymphoid-like structures (TA-TLS), which are the local site of humoral and cellular immune response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b2effc260f0374253c600f9266982b2
https://doi.org/10.1101/2021.12.24.474088
https://doi.org/10.1101/2021.12.24.474088
Autor:
Yichao, Hua, Gerlanda, Vella, Florian, Rambow, Elizabeth, Allen, Asier, Antoranz Martinez, Marie, Duhamel, Akira, Takeda, Sirpa, Jalkanen, Steffie, Junius, Ann, Smeets, David, Nittner, Stefanie, Dimmeler, Thomas, Hehlgans, Adrian, Liston, Francesca Maria, Bosisio, Giuseppe, Floris, Damya, Laoui, Maija, Hollmén, Diether, Lambrechts, Pascal, Merchiers, Jean-Christophe, Marine, Susan, Schlenner, Gabriele, Bergers
Publikováno v:
Cancer cell. 40(12)
The lack of T cell infiltrates is a major obstacle to effective immunotherapy in cancer. Conversely, the formation of tumor-associated tertiary-lymphoid-like structures (TA-TLLSs), which are the local site of humoral and cellular immune responses aga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::27bc8b3d0cb87d6ca5d2e8fad93987ed
https://pubmed.ncbi.nlm.nih.gov/36423635
https://pubmed.ncbi.nlm.nih.gov/36423635
Autor:
Yichao Hua, Gerlanda Vella, Florian Rambow, Elizabeth Allen, Asier Antoranz Martinez, Marie Duhamel, Akira Takeda, Sirpa Jalkanen, Steffie Junius, Ann Smeets, David Nittner, Stefanie Dimmeler, Thomas Hehlgans, Adrian Liston, Francesca Maria Bosisio, Giuseppe Floris, Damya Laoui, Maija Hollmén, Diether Lambrechts, Pascal Merchiers, Jean-Christophe Marine, Susan Schlenner, Gabriele Bergers
Publikováno v:
Cancer Cell. 40:1600-1618.e10
The lack of T cell infiltrates is a major obstacle to effective immunotherapy in cancer. Conversely, the formation of tumor-associated tertiary-lymphoid-like structures (TA-TLLSs), which are the local site of humoral and cellular immune responses aga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb1e5fa5412310359e0525e3f9913994
https://doi.org/10.1016/j.ccell.2022.11.002
https://doi.org/10.1016/j.ccell.2022.11.002
Autor:
Gerlanda Vella, Yichao Hua, Florian Rambow, Elizabeth Allen, Asier Antoranz Martinez, Pascal Merchiers, Francesca Bosisio, Giuseppe Floris, Akira Takeda, Sirpa Jalkanen, Maija Hollmén, Jean-Christophe Marine, Susan Schlenner, Gabriele Bergers
Publikováno v:
Cancer Immunology Research. 10:A34-A34
The lack of T-cell infiltrates is a major obstacle to effective immunotherapy in cancer. Conversely, the formation of tumor-associated tertiary-lymphoid-like structures (TA-TLS), which are the local site of humoral and cellular immune responses again
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0832021fd5b1db702e7cda4f52579fc0
https://doi.org/10.1158/2326-6074.tumimm22-a34
https://doi.org/10.1158/2326-6074.tumimm22-a34
Autor:
Isabelle, Solomon, Maria, Amann, Anne, Goubier, Frederick, Arce Vargas, Dimitrios, Zervas, Chen, Qing, Jake Y, Henry, Ehsan, Ghorani, Ayse U, Akarca, Teresa, Marafioti, Anna, Śledzińska, Mariana, Werner Sunderland, Dafne, Franz Demane, Joanne Ruth, Clancy, Andrew, Georgiou, Josephine, Salimu, Pascal, Merchiers, Mark Adrian, Brown, Reto, Flury, Jan, Eckmann, Claudio, Murgia, Johannes, Sam, Bjoern, Jacobsen, Estelle, Marrer-Berger, Christophe, Boetsch, Sara, Belli, Lea, Leibrock, Joerg, Benz, Hans, Koll, Roger, Sutmuller, Karl S, Peggs, Sergio A, Quezada
Publikováno v:
Nature cancer. 1(12)
Intratumoral regulatory T cell (Treg) abundance associates with diminished anti-tumor immunity and poor prognosis in human cancers. Recent work demonstrates that CD25, the high affinity receptor subunit for IL-2, is a selective target for Treg deplet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1e9ea9c92fedf39f7b34d066c9a8585a
https://pubmed.ncbi.nlm.nih.gov/35121936
https://pubmed.ncbi.nlm.nih.gov/35121936
Autor:
Niels Vandamme, Louis Boon, Jo A. Van Ginderachter, Maude Jans, Damya Laoui, Yvon Elkrim, Pauline M. R. Bardet, Evangelia Bolli, Mate Kiss, Bart Neyns, Aleksandar Murgaski, Elizabeth Allen, Bruno Dombrecht, Sebahat Ocak, Heleen Roose, Lars Vereecke, Frank Aboubakar Nana, Pascal Merchiers, James Dooley, Helena Van Damme, Daliya Kancheva, Maria Solange Martins, Gillian Blancke, Frank Tacke, Eva Van Overmeire, Isabelle Scheyltjens, Kiavash Movahedi, Julia Katharina Schwarze, Liesbet Martens
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 2 (2021)
JOURNAL FOR IMMUNOTHERAPY OF CANCER
Journal for Immunotherapy of Cancer
JOURNAL FOR IMMUNOTHERAPY OF CANCER
Journal for Immunotherapy of Cancer
BackgroundModulation and depletion strategies of regulatory T cells (Tregs) constitute valid approaches in antitumor immunotherapy but suffer from severe adverse effects due to their lack of selectivity for the tumor-infiltrating (ti-)Treg population
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec8e764f930f6b9dd6108bd2cf028b8f
https://jitc.bmj.com/content/9/2/e001749.full
https://jitc.bmj.com/content/9/2/e001749.full
Autor:
Chris D Emmerson, Els J van der Vlist, Myrthe R Braam, Peter Vanlandschoot, Pascal Merchiers, Hans J W de Haard, C Theo Verrips, Paul M P van Bergen en Henegouwen, Edward Dolk
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26299 (2011)
The polymeric immunoglobulin receptor (pIgR) ensures the transport of dimeric immunoglobulin A (dIgA) and pentameric immunoglobulin M (pIgM) across epithelia to the mucosal layer of for example the intestines and the lungs via transcytosis. Per day t
Externí odkaz:
https://doaj.org/article/47bd55659bc0464fa0a1c43a37e7cfc1
Autor:
An Tanghe, Annelies Termont, Pascal Merchiers, Stephan Schilling, Hans-Ulrich Demuth, Louise Scrocchi, Fred Van Leuven, Gerard Griffioen, Tom Van Dooren
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2010 (2010)
The APP[V717I] London (APP-Ld) mouse model recapitulates important pathological and clinical hallmarks of Alzheimer's disease (AD) and is therefore a valuable paradigm for evaluating therapeutic candidates. Historically, both the parenchymal and vasc
Externí odkaz:
https://doaj.org/article/a5197c7e75b44c5e80b34ab6b80b4a30