Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Pascal, Gelebart"'
Autor:
Marcus J. G. W. Ladds, Ingeborg M. M. van Leeuwen, Catherine J. Drummond, Su Chu, Alan R. Healy, Gergana Popova, Andrés Pastor Fernández, Tanzina Mollick, Suhas Darekar, Saikiran K. Sedimbi, Marta Nekulova, Marijke C. C. Sachweh, Johanna Campbell, Maureen Higgins, Chloe Tuck, Mihaela Popa, Mireia Mayoral Safont, Pascal Gelebart, Zinayida Fandalyuk, Alastair M. Thompson, Richard Svensson, Anna-Lena Gustavsson, Lars Johansson, Katarina Färnegårdh, Ulrika Yngve, Aljona Saleh, Martin Haraldsson, Agathe C. A. D’Hollander, Marcela Franco, Yan Zhao, Maria Håkansson, Björn Walse, Karin Larsson, Emma M. Peat, Vicent Pelechano, John Lunec, Borivoj Vojtesek, Mar Carmena, William C. Earnshaw, Anna R. McCarthy, Nicholas J. Westwood, Marie Arsenian-Henriksson, David P. Lane, Ravi Bhatia, Emmet McCormack, Sonia Laín
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/0c0c030dc1c54c61a794787a99cca008
Autor:
May Eriksen‐Gjerstad, Ida Tveit Karlsen, Zinayida Fandalyuk, Susanne Benjaminsen, Fanny Baran‐Marszak, Bela Papp, Frederick Locke, Marcus Ladds, Andrés Pastor‐Fernández, Pascal Gelebart, Emmet Mc Cormack
Publikováno v:
eJHaem, Vol 3, Iss 3, Pp 913-918 (2022)
Abstract Mantle cell lymphoma (MCL) is a non‐Hodgkin lymphoma that remains incurable with the treatment options available today. In the present study, we have identified the dihydroorotate dehydrogenase (DHODH), an essential enzyme for the de novo
Externí odkaz:
https://doaj.org/article/89fe4f4068a64767b83320ef7c88e86c
Autor:
Marcus J. G. W. Ladds, Ingeborg M. M. van Leeuwen, Catherine J. Drummond, Su Chu, Alan R. Healy, Gergana Popova, Andrés Pastor Fernández, Tanzina Mollick, Suhas Darekar, Saikiran K. Sedimbi, Marta Nekulova, Marijke C. C. Sachweh, Johanna Campbell, Maureen Higgins, Chloe Tuck, Mihaela Popa, Mireia Mayoral Safont, Pascal Gelebart, Zinayida Fandalyuk, Alastair M. Thompson, Richard Svensson, Anna-Lena Gustavsson, Lars Johansson, Katarina Färnegårdh, Ulrika Yngve, Aljona Saleh, Martin Haraldsson, Agathe C. A. D’Hollander, Marcela Franco, Yan Zhao, Maria Håkansson, Björn Walse, Karin Larsson, Emma M. Peat, Vicent Pelechano, John Lunec, Borivoj Vojtesek, Mar Carmena, William C. Earnshaw, Anna R. McCarthy, Nicholas J. Westwood, Marie Arsenian-Henriksson, David P. Lane, Ravi Bhatia, Emmet McCormack, Sonia Laín
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Abstract The development of non-genotoxic therapies that activate wild-type p53 in tumors is of great interest since the discovery of p53 as a tumor suppressor. Here we report the identification of over 100 small-molecules activating p53 in cells. We
Externí odkaz:
https://doaj.org/article/c70bab1df6ec4076bb2c93aa455abeeb
Autor:
Christiane Helgestad Gjerde, Anika Langer, Gorka Ruiz de Garibay Ponce, Katrin Kleinmanns, Harsh Nitin Dongre, Rammah Elnour Mustafa, Constantin Berger, Robert Willoughby, Elvira García de Jalón, Okan Gultekin, Erdem Bozluolcay, Ben Davidson, Pascal Gelebart, Daniela Elena Costea, Kaisa Lehti, Emmet McCormack, Line Bjørge
Publikováno v:
Translational research/biomarkers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77ecb5c48cb80a610a8b3731288fd0ce
https://doi.org/10.1136/ijgc-2022-esgo.869
https://doi.org/10.1136/ijgc-2022-esgo.869
Autor:
Marcus J. G. W. Ladds, Ingeborg M. M. van Leeuwen, Catherine J. Drummond, Su Chu, Alan R. Healy, Gergana Popova, Andrés Pastor Fernández, Tanzina Mollick, Suhas Darekar, Saikiran K. Sedimbi, Marta Nekulova, Marijke C. C. Sachweh, Johanna Campbell, Maureen Higgins, Chloe Tuck, Mihaela Popa, Mireia Mayoral Safont, Pascal Gelebart, Zinayida Fandalyuk, Alastair M. Thompson, Richard Svensson, Anna-Lena Gustavsson, Lars Johansson, Katarina Färnegårdh, Ulrika Yngve, Aljona Saleh, Martin Haraldsson, Agathe C. A. D’Hollander, Marcela Franco, Yan Zhao, Maria Håkansson, Björn Walse, Karin Larsson, Emma M. Peat, Vicent Pelechano, John Lunec, Borivoj Vojtesek, Mar Carmena, William C. Earnshaw, Anna R. McCarthy, Nicholas J. Westwood, Marie Arsenian-Henriksson, David P. Lane, Ravi Bhatia, Emmet McCormack, Sonia Laín
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-2 (2018)
The original PDF version of this Article listed the authors as “Marcus J.G.W. Ladds,” where it should have read “Marcus J. G. W. Ladds, Ingeborg M. M. van Leeuwen, Catherine J. Drummond et al.#”. Also in the PDF version, it was incorrectly st
Externí odkaz:
https://doaj.org/article/6b88c0d66cd64b709fb079a6627015c7
Autor:
Bjørn Tore Gjertsen, Anders Molven, Kaoru Tohyama, Mihaela Popa, Astrid Olsnes Kittang, Monica Hellesøy, Biju Parekkadan, Rakel Brendsdal Forthun, Jungwoo Lee, Sahba Shafiee, Randi Hovland, Pascal Gelebart, Emmet McCormack
Publikováno v:
Br J Haematol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f33ebf6b01b15d8268fae445f102f9f
https://doi.org/10.1111/bjh.17372
https://doi.org/10.1111/bjh.17372
Autor:
Katrin Kleinmanns, Christiane Helgestad Gjerde, Anika Langer, Vibeke Fosse, Elvira García de Jalón, Calum Leitch, Mihaela Popa, Pascal Gelebart, Emmet McCormack
Publikováno v:
Biomarkers of the Tumor Microenvironment ISBN: 9783030989491
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e31d36f09c78945c6868047bc020c898
https://doi.org/10.1007/978-3-030-98950-7_19
https://doi.org/10.1007/978-3-030-98950-7_19
Autor:
Anne Quinquenel, Julie Tran, Pascal Gelebart, Nadine Varin-Blank, Laura Gardano, Florence Cymbalista, Dominique Ledoux, Carole Fleury, Souhail Ouriemmi, Catherine Thieblemont, Emmet McCormack, David Chiron, Imane Mihoub, Chloé Friedrich, Fanny Baran-Marszak, Celine Bellanger, Antoine Martin, Elisabetta Dondi, Gregory Lazarian, Jacek Marzec, John G. Gribben
Publikováno v:
Oncogene
Oncogene, Nature Publishing Group, 2020, 39 (14), pp.2934-2947. ⟨10.1038/s41388-020-1183-x⟩
Oncogene, 2020, 39 (14), pp.2934-2947. ⟨10.1038/s41388-020-1183-x⟩
Oncogene, Nature Publishing Group, 2020, 39 (14), pp.2934-2947. ⟨10.1038/s41388-020-1183-x⟩
Oncogene, 2020, 39 (14), pp.2934-2947. ⟨10.1038/s41388-020-1183-x⟩
International audience; B-cell receptor (BCR) signaling pathways and interactions with the tumor microenvironment account for mantle cell lymphoma (MCL) cells survival in lymphoid organs. In several MCL cases, the WNT/β-catenin canonical pathway is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbbf29303e70b9d0a44741c9d0db98f7
https://www.hal.inserm.fr/inserm-02534412
https://www.hal.inserm.fr/inserm-02534412
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e33738 (2012)
Fatty acid synthase (FASN), a key player in the de novo synthetic pathway of long-chain fatty acids, has been shown to contribute to the tumorigenesis in various types of solid tumors. We here report that FASN is highly and consistently expressed in
Externí odkaz:
https://doaj.org/article/34016d09cef94804b4d98908f7fd97d2
Autor:
Karin Larsson, Tanzina Mollick, Richard Svensson, Mireia Mayoral Safont, Emma M. Peat, Yan Zhao, Anna Lena Gustavsson, Chloe Tuck, David P. Lane, Gergana Popova, Anna R. McCarthy, Katarina Färnegårdh, Maureen Higgins, John Lunec, Ulrika Yngve, Marcus J.G.W. Ladds, Andrés Pastor Fernández, Nicholas J. Westwood, Emmet McCormack, Alan R. Healy, Ingeborg M.M. van Leeuwen, Suhas Darekar, Catherine J. Drummond, Martin Haraldsson, Pascal Gelebart, Mihaela Popa, Marijke C.C. Sachweh, Lars Johansson, Sonia Lain, Ravi Bhatia, Zinayida Fandalyuk, Vicent Pelechano, Agathe C.A. D'Hollander, Borivoj Vojtesek, Su Chu, Mar Carmena, William C. Earnshaw, Alastair M. Thompson, Saikiran K. Sedimbi, Marta Nekulova, Maria Håkansson, Aljona Saleh, Marie Arsenian-Henriksson, Johanna Campbell, Marcela Franco, Björn Walse
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications
Ladds, M J G W, van Leeuwen, I M M, Drummond, C J, Chu, S, Healy, A R, Popova, G, Pastor Fernández, A, Mollick, T, Darekar, S, Sedimbi, S K, Nekulova, M, Sachweh, M C C, Campbell, J, Higgins, M, Tuck, C, Popa, M, Safont, M M, Gelebart, P, Fandalyuk, Z, Thompson, A M, Svensson, R, Gustavsson, A-L, Johansson, L, Färnegårdh, K, Yngve, U, Saleh, A, Haraldsson, M, D'Hollander, A C A, Franco, M, Zhao, Y, Håkansson, M, Walse, B, Larsson, K, Peat, E M, Pelechano, V, Lunec, J, Vojtesek, B, Carmena, M, Earnshaw, W C, McCarthy, A R, Westwood, N J, Arsenian-Henriksson, M, Lane, D P, Bhatia, R, McCormack, E & Laín, S 2018, ' A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage ', Nature Communications, vol. 9, no. 1, 1107 (2018) . https://doi.org/10.1038/s41467-018-03441-3
Nature Communications
Ladds, M J G W, van Leeuwen, I M M, Drummond, C J, Chu, S, Healy, A R, Popova, G, Pastor Fernández, A, Mollick, T, Darekar, S, Sedimbi, S K, Nekulova, M, Sachweh, M C C, Campbell, J, Higgins, M, Tuck, C, Popa, M, Safont, M M, Gelebart, P, Fandalyuk, Z, Thompson, A M, Svensson, R, Gustavsson, A-L, Johansson, L, Färnegårdh, K, Yngve, U, Saleh, A, Haraldsson, M, D'Hollander, A C A, Franco, M, Zhao, Y, Håkansson, M, Walse, B, Larsson, K, Peat, E M, Pelechano, V, Lunec, J, Vojtesek, B, Carmena, M, Earnshaw, W C, McCarthy, A R, Westwood, N J, Arsenian-Henriksson, M, Lane, D P, Bhatia, R, McCormack, E & Laín, S 2018, ' A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage ', Nature Communications, vol. 9, no. 1, 1107 (2018) . https://doi.org/10.1038/s41467-018-03441-3
ML, CD, IvL, GP, TM, SD, MS, APF, CT, DL, MAH, KL and SL: project grants from the Swedish Research Council, the Swedish Cancer Society and the Swedish Childhood Cancer Foundation. MHi and JC: Cancer Research UK (C8/A6613). MC, EP and WE: Wellcome Tru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dd2c01d2aabbdecaf13d8d9d9ac446c
http://link.springer.com/article/10.1038/s41467-018-03441-3
http://link.springer.com/article/10.1038/s41467-018-03441-3