Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Pascal, Fragner"'
Autor:
Elie Frank, Michel Cailleret, Constantin Nelep, Pascal Fragner, Jérome Polentes, Elise Herardot, Lina El Kassar, Karine Giraud-Triboult, Christelle Monville, Karim Ben M’Barek
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Background CRISPR/Cas9 editing systems are currently used to generate mutations in a particular gene to mimic a genetic disorder in vitro. Such “disease in a dish” models based on human pluripotent stem cells (hPSCs) offer the opportunit
Externí odkaz:
https://doaj.org/article/a0978364e13741ee98c9f4e6a67499fa
Autor:
Lucille Rossiaud, Pascal Fragner, Elena Barbon, Antoine Gardin, Manon Benabides, Emilie Pellier, Jérémie Cosette, Lina El Kassar, Karine Giraud-Triboult, Xavier Nissan, Giuseppe Ronzitti, Lucile Hoch
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Introduction: Glycogen storage disease type III (GSDIII) is a rare genetic disease caused by mutations in the AGL gene encoding the glycogen debranching enzyme (GDE). The deficiency of this enzyme, involved in cytosolic glycogen degradation, leads to
Externí odkaz:
https://doaj.org/article/3fb7ea44045d4969bdae8d1733b5cf40
Autor:
Jinah Han, Charles-Félix Calvo, Tae Hyuk Kang, Kasey L. Baker, June-Hee Park, Carlos Parras, Marine Levittas, Ulrick Birba, Laurence Pibouin-Fragner, Pascal Fragner, Kaya Bilguvar, Ronald S. Duman, Harri Nurmi, Kari Alitalo, Anne C. Eichmann, Jean-Léon Thomas
Publikováno v:
Cell Reports, Vol 10, Iss 7, Pp 1158-1172 (2015)
Neural stem cells (NSCs) continuously produce new neurons within the adult mammalian hippocampus. NSCs are typically quiescent but activated to self-renew or differentiate into neural progenitor cells. The molecular mechanisms of NSC activation remai
Externí odkaz:
https://doaj.org/article/315ad1d0e24c4d85a80af7b8470c6a50
Autor:
Yacine Laâbi, Johana Tournois, Julien Côme, Pascal Fragner, Michel Cailleret, Philippe Tropel, Christine Varela, Marc Peschanski, Céline Moutou, Stéphane Viville
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 46:376-385
Pre-implantation genetic diagnosis allows the characterisation of embryos that carry a gene responsible for a severe monogenic disease and to transfer to the mother’s uterus only the unaffected one(s). The genetically affected embryos can be used t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88dbf0bf1add0d95f70a10735bae7011
https://doi.org/10.1007/s11626-010-9300-8
https://doi.org/10.1007/s11626-010-9300-8
Autor:
Claire Mercier, Françoise Roux, Christophe Masseguin, Pascal Fragner, Marcienne Tardy, Xavier Declèves, Jacqueline Gabrion, Jean-Michel Scherrmann
Publikováno v:
Journal of Neurochemistry. 87:820-830
At least two drug efflux pumps involved in multidrug resistance, P-glycoprotein (P-gp) and multidrug resistance-associated protein 1 (Mrp1), are expressed in rat astrocyte primary cultures. The aim of this study was to compare the expression of P-gp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::884ad97562f75fb6f36d33277f0575b4
https://doi.org/10.1046/j.1471-4159.2003.02034.x
https://doi.org/10.1046/j.1471-4159.2003.02034.x
Autor:
Pascal Fragner, Françoise Roux, L. Payen, Claire Mercier, C. Leroy-Noury, Pierre-Olivier Couraud, P. Demeuse, O. Fardel
Publikováno v:
Journal of Neurochemistry. 88:23-31
The blood–brain barrier (BBB) plays an important role in controlling the passage of molecules from blood to brain extracellular fluid. The multidrug efflux pump P-glycoprotein (P-gp) is highly expressed in the luminal membrane of brain endothelium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c72c4bd5f3a4ed563dc4cf8a92a4122c
https://doi.org/10.1046/j.1471-4159.2003.02071.x
https://doi.org/10.1046/j.1471-4159.2003.02071.x
Publikováno v:
Endocrinology. 140:4113-4119
TRH is localized with insulin in β-cells. It is synthesized as a prohormone containing five copies of TRH and seven cryptic peptides, including pro (p)-TRH-(160–169). Thyroid hormone regulates the expression of several genes encoding peptide hormo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa235360b696121329d33d1fee3c25ff
https://doi.org/10.1210/endo.140.9.6952
https://doi.org/10.1210/endo.140.9.6952
Publikováno v:
Biochemical and Biophysical Research Communications. 247:564-568
Thyrotropin-releasing hormone (TRH), originally characterized as the first hypothalamic hormone, is also synthesized in the insulin-containing cells. TRH stimulates the glucagon secretion and attenuates exocrine pancreatic secretions. We have previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18f35e1fb7dabcb046b6cda022cb9471
https://doi.org/10.1006/bbrc.1998.8830
https://doi.org/10.1006/bbrc.1998.8830
Autor:
Morwena Latouche, Cecilia Zander, Giovanni Stevanin, Merle Ruberg, Pascal Fragner, Annie Sittler, Elodie Martin, Khalid Hamid El Hachimi, Alexis Brice
Publikováno v:
Molecular and cellular neurosciences. 31(3)
Spinocerebellar ataxia type 7 (SCA7) is caused by expansion of a (CAG)n repeat in the ataxin7 gene, resulting in an abnormally long polyglutamine polyQ tract in the translated protein that aggregates in the form of neuronal intranuclear inclusions. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf23ad50ad461dcf6724cd6f7ee76040
https://pubmed.ncbi.nlm.nih.gov/16325416
https://pubmed.ncbi.nlm.nih.gov/16325416
Autor:
Claire, Mercier, Xavier, Declèves, Christophe, Masseguin, Pascal, Fragner, Marcienne, Tardy, Françoise, Roux, Jacqueline, Gabrion, Jean-Michel, Scherrmann
Publikováno v:
Journal of neurochemistry. 87(4)
At least two drug efflux pumps involved in multidrug resistance, P-glycoprotein (P-gp) and multidrug resistance-associated protein 1 (Mrp1), are expressed in rat astrocyte primary cultures. The aim of this study was to compare the expression of P-gp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dea42c645b1308f7dabb9db92272579b
https://pubmed.ncbi.nlm.nih.gov/14622113
https://pubmed.ncbi.nlm.nih.gov/14622113