Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Pascal, Darbon"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Externí odkaz:
https://doaj.org/article/f4f17b666e4d4903ad607512cbccf292
Autor:
Mai Iwasaki, Arthur Lefevre, Ferdinand Althammer, Etienne Clauss Creusot, Olga Łąpieś, Hugues Petitjean, Louis Hilfiger, Damien Kerspern, Meggane Melchior, Stephanie Küppers, Quirin Krabichler, Ryan Patwell, Alan Kania, Tim Gruber, Matthew K. Kirchner, Moritz Wimmer, Henning Fröhlich, Laura Dötsch, Jonas Schimmer, Sabine C. Herpertz, Beate Ditzen, Christian P. Schaaf, Kai Schönig, Dusan Bartsch, Anna Gugula, Aleksandra Trenk, Anna Blasiak, Javier E. Stern, Pascal Darbon, Valery Grinevich, Alexandre Charlet
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
The hypothalamic neuropeptide oxytocin exerts analgesic effects, but the underlying pathways remain largely elusive. Here, the authors describe an analgesic pathway formed by oxytocin neurons projecting to the periaqueductal grey, where axonally rele
Externí odkaz:
https://doaj.org/article/85fa7e14fa3741ae8af552981e58801d
Autor:
Angel Baudon, Etienne Clauss-Creusot, Pascal Darbon, Ryan Patwell, Valery Grinevich, Alexandre Charlet
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101159- (2022)
Summary: Astrocytes are glial cells that exhibit calcium signaling-mediated activity. Here, we present a protocol to monitor and manipulate astrocyte calcium activity from mouse amygdala slices. In the first part of this protocol, we describe the pro
Externí odkaz:
https://doaj.org/article/f0bf98f2d3a04a62846159f2ffdc37a3
Autor:
Louis Hilfiger, Zélie Triaux, Christophe Marcic, Eléa Héberlé, Fathi Emhemmed, Pascal Darbon, Eric Marchioni, Hugues Petitjean, Alexandre Charlet
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Context: Menthol, the main monoterpene found in Mentha piperita L. (M. piperita) is known to modulate nociceptive threshold and is present in different curative preparations that reduce sensory hypersensitivities in pain conditions. While for pulegon
Externí odkaz:
https://doaj.org/article/8a6ff5354e9e4a908d0f21556b2e440c
Autor:
Marit Knoop, Marie-Laure Possovre, Alice Jacquens, Alexandre Charlet, Olivier Baud, Pascal Darbon
Publikováno v:
Cells, Vol 11, Iss 23, p 3899 (2022)
The neonatal period is critical for brain development and determinant for long-term brain trajectory. Yet, this time concurs with a sensitivity and risk for numerous brain injuries following perinatal complications such as preterm birth. Brain injury
Externí odkaz:
https://doaj.org/article/76f88a19555141a69e918d37e59bd394
Autor:
Florian Gabel, Anne-Sophie Aubry, Volodya Hovhannisyan, Virginie Chavant, Ivan Weinsanto, Tando Maduna, Pascal Darbon, Yannick Goumon
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Background: Tamoxifen is used to treat breast cancer and cancer recurrences. After administration, tamoxifen is converted into two more potent antitumor compounds, 4OH-tamoxifen and endoxifen by the CYP3A4/5 and 2D6 enzymes in human. These active com
Externí odkaz:
https://doaj.org/article/92fd90d05a924de9a5fef797b2d64d8f
Autor:
Mai Iwasaki, Arthur Lefevre, Ferdinand Althammer, Olga Łąpieś, Louis Hilfiger, Damien Kerspern, Meggane Melchior, Stephanie Küppers, Quirin Krablicher, Ryan Patwell, Sabine C Herpertz, Beate Ditzen, Kai Schönig, Dusan Bartsch, Javier E. Stern, Pascal Darbon, Valery Grinevich, Alexandre Charlet
The hypothalamic neuropeptide, oxytocin (OT), exerts prominent analgesic effects via central and peripheral action. Here we discovered a novel subset of OT neurons whose projections preferentially terminate on OT receptor (OTR)-expressing neurons in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0885f09c408eca9947743e88da35a77a
https://doi.org/10.1101/2022.02.23.481531
https://doi.org/10.1101/2022.02.23.481531
Autor:
Alexandre Charlet, Eric Marchioni, Fathi Emhemmed, Pascal Darbon, Louis Hilfiger, Hugues Petitjean, Christophe Marcic, Zélie Triaux
Monoterpenes are small molecules, composed of two isoprene units, able to pass through the blood brain barrier, allowing to target both peripheral and central pain pathways. They are the main components of essential oils, responsible for their divers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fd8993093c1f2e7692347feab399525
https://doi.org/10.21203/rs.3.rs-538863/v1
https://doi.org/10.21203/rs.3.rs-538863/v1
Autor:
Isabelle Decosterd, Angel Baudon, Ron Stoop, Daisuke Hagiwara, Pascal Darbon, W. Scott Young, Marie Pertin, Perrine Inquimbert, Ranjan K. Roy, Jean-Yves Chatton, Damien Kerspern, Stéphanie Goyon, Valery Grinevich, Marios Abatis, Ferdinand Althammer, Pierrick Poisbeau, Ivan Weinsanto, Matthew K. Kirchner, Javier E. Stern, Miriam da Silva Gouveia, Marina Eliava, Diego Benusiglio, Claudia Pitzer, Arthur Lefevre, Yannick Goumon, Jérôme Wahis, Christophe M. Lamy, Benjamin Bellanger, Alexandre Charlet, Jan Siemens, Hanna Sophie Knobloch-Bollmann, Nathalie Rouach, Hong Wang, Andrei Rozov, Benjamin Boury-Jamot, Lara Barteczko, Benjamin Boutrel
Publikováno v:
Nature Neuroscience
Nature Neuroscience, Nature Publishing Group, 2021, ⟨10.1038/s41593-021-00800-0⟩
Nature Neuroscience, 2021, 24 (4), pp.529-541. ⟨10.1038/s41593-021-00800-0⟩
Nature Neuroscience, Nature Publishing Group, 2021, ⟨10.1038/s41593-021-00800-0⟩
Nature Neuroscience, 2021, 24 (4), pp.529-541. ⟨10.1038/s41593-021-00800-0⟩
International audience; Oxytocin (OT) orchestrates social and emotional behaviors through modulation of neural circuits. In the central amygdala, the release of OT modulates inhibitory circuits and, thereby, suppresses fear responses and decreases an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a98f11979e01a588ccd2c2b6021ce42
https://hal.archives-ouvertes.fr/hal-03178553
https://hal.archives-ouvertes.fr/hal-03178553