Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Pasan Fernando"'
Autor:
Erin J Vanzyl, Hadil Sayed, Alex B Blackmore, Kayleigh R C Rick, Pasan Fernando, Bruce C McKay
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0224953 (2020)
The spliceosome assembles on pre-mRNA in a stepwise manner through five successive pre-spliceosome complexes. The spliceosome functions to remove introns from pre-mRNAs to generate mature mRNAs that encode functional proteins. Many small molecule inh
Externí odkaz:
https://doaj.org/article/90ec183a8f8c474faf2968abd8490439
Autor:
Pasan Fernando, Hadil Sayed, Bruce C. McKay, Erin J. Vanzyl, Kayleigh R C Rick, Alex B. Blackmore
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 12, p e0224953 (2020)
PLoS ONE, Vol 15, Iss 12, p e0224953 (2020)
The spliceosome assembles on pre-mRNA in a stepwise manner through five successive pre-spliceosome complexes. The spliceosome functions to remove introns from pre-mRNAs to generate mature mRNAs that encode functional proteins. Many small molecule inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cceb7db7d08b9ec8033a1ab2d77cb4c8
http://europepmc.org/articles/PMC7769279
http://europepmc.org/articles/PMC7769279
Autor:
Jonathan J. Weldrick, Pasan Fernando, Steve Brunette, Duncan J. Stewart, Yupu Deng, Colin Suen, Frans H. H. Leenen, Mohammad Abdul-Ghani, Peter Flynn, Patrick G. Burgon, Tom Tong Lee, Charis Putinski, Lynn A. Megeney, Baohua Jiang
Publikováno v:
Cell Research
The post-natal heart adapts to stress and overload through hypertrophic growth, a process that may be pathologic or beneficial (physiologic hypertrophy). Physiologic hypertrophy improves cardiac performance in both healthy and diseased individuals, y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2745a55300d2e2aaa83faa97baadcab
https://doi.org/10.1038/cr.2017.87
https://doi.org/10.1038/cr.2017.87
Autor:
Annegret Dahlmann-Noor, Stephen J. Tuft, Melanie Hingorani, Elisa Marziali, Marta Chlubek, Pasan Fernando, Daniel F P Larkin
Publikováno v:
Eye (Lond)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8ff0a0529fc34027f6e9da26826226
https://doi.org/10.1038/s41433-020-1062-2
https://doi.org/10.1038/s41433-020-1062-2
Publikováno v:
Abstracts.
Background Vernal keratoconjunctivitis (VKC) and atopic keratoconjunctivitis (AKC) are severe allergic diseases of the ocular surface which can have sight-threatening complications such as shield-shaped ulcers and plaques. Paediatricians, general pra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba3e52bbd0e1b85f562aae5555743050
https://doi.org/10.1136/archdischild-2019-epa.366
https://doi.org/10.1136/archdischild-2019-epa.366
Autor:
Terrence D. Ruddy, Corinne Bensimon, Julia Petryk, Brian Marvin, Karen Soueidan, Yin Duan, R. Glenn Wells, Rachel Timmins, Pasan Fernando, Lihui Wei
Publikováno v:
Journal of Nuclear Medicine. 56:764-770
Rotenone derivatives have shown promise in myocardial perfusion imaging (MPI). CMICE-013 is a novel 123I-labeled rotenone derivative developed for SPECT MPI. The objective of this study was to assess the image quality of CMICE-013 and compare its upt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ef7581c01f20b2e8426e4135adcdb43
https://doi.org/10.2967/jnumed.114.151563
https://doi.org/10.2967/jnumed.114.151563
Autor:
Vision, Todd, Balhoff, James, Dahdul, Wasila, Dececchi, Alex, Mastick, Kellen, Pasan Fernando, Lapp, Hilmar, Mabee, Paula, Prashanti Manda, Westerfield, Monte, Erliang Zeng
The Devonian era transition from aquatic fins to terrestrial limbs in tetrapodamorph vertebrates is well-studied in the fossil record, and the genes responsible for the complex suite of anatomical changes have been the topic of much speculation. A re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::006d2538853f7d83a4e0973a3727a042
Autor:
Yin Duan, Xuxu Yan, Yong-Xiang Chen, Terrence D. Ruddy, Corinne Bensimon, Lihui Wei, Julia Lockwood, J. Russell Redshaw, Peter A. Covitz, R. Glenn Wells, Pasan Fernando
Publikováno v:
Bioorganic & Medicinal Chemistry. 21:2903-2911
Coronary artery disease (CAD) is a major cause of death in Canada and the United States. Single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) is a useful diagnostic test in the management of patients with CAD. The wid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e227a1d3954e2334a1d6c0fa0511509c
https://doi.org/10.1016/j.bmc.2013.03.080
https://doi.org/10.1016/j.bmc.2013.03.080
Autor:
Michael A. Rudnicki, C. Florian Bentzinger, Frank Grosveld, Ghadi Antoun, Hang Yin, Alessandra Pasut, Mary-Ellen Harper, Patrick Seale, Wilfred F. J. van IJcken, Vahab D. Soleimani, Stephanie Thorn, Pasan Fernando, Robert A. deKemp, Robert Boushel
Publikováno v:
Cell Metabolism, 17(2), 210-224. Cell Press
SummaryBrown adipose tissue (BAT) is an energy-dispensing thermogenic tissue that plays an important role in balancing energy metabolism. Lineage-tracing experiments indicate that brown adipocytes are derived from myogenic progenitors during embryoni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7edf09fea2eb7cb64ef370bffaa2bd5
https://doi.org/10.1016/j.cmet.2013.01.004
https://doi.org/10.1016/j.cmet.2013.01.004
Autor:
Pasan Fernando, Eric Lamsa, Corinne Bensimon, Garry E. Kiefer, Paul Jurek, Katharina Guenther, Myra Kordos, Yin Duan, Michael O. Woods, Cara L. Ferreira
Publikováno v:
Bioconjugate Chemistry. 21:531-536
Ga radioisotopes, including the generator-produced positron-emitting isotope (68)Ga (t1/2 = 68 min), are of increasing interest for the development of new radiopharmaceuticals. Bifunctional chelates (BFCs) that can be efficiently radiolabeled with Ga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d9b035b6f46a524188f29a5313e75ee
https://doi.org/10.1021/bc900443a
https://doi.org/10.1021/bc900443a