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Multi-OMIC analysis of Huntington disease reveals a neuroprotective astrocyte state.

Autor: Paryani F; Department of Neurology, Columbia University Irving Medical Center., Kwon JS; Washington University School of Medicine in St. Louis., Ng CW; Massachusetts Institute of Technology, Department of Biological Engineering., Madden N; Department of Pathology and Cell Biology, Columbia University Irving Medical Center., Ofori K; Department of Pathology and Cell Biology, Columbia University Irving Medical Center., Tang A; Department of Pathology and Cell Biology, Columbia University Irving Medical Center., Lu H; Department of Pathology and Cell Biology, Columbia University Irving Medical Center., Li J; Department of Pathology and Cell Biology, Columbia University Irving Medical Center., Mahajan A; Department of Pathology and Cell Biology, Columbia University Irving Medical Center., Davidson SM; Princeton University, Lewis-Sigler Institute for Integrative Genomics., Basile A; New York Genome Center., McHugh C; New York Genome Center., Vonsattel JP; Department of Pathology and Cell Biology, Columbia University Irving Medical Center., Hickman R; Department of Pathology and Cell Biology, Columbia University Irving Medical Center., Zody M; New York Genome Center., Houseman DE; Massachusetts Institute of Technology, Department of Biological Engineering., Goldman JE; Department of Pathology and Cell Biology, Columbia University Irving Medical Center., Yoo AS; Washington University School of Medicine in St. Louis., Menon V; Department of Neurology, Columbia University Irving Medical Center., Al-Dalahmah O; Department of Pathology and Cell Biology, Columbia University Irving Medical Center.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Sep 12. Date of Electronic Publication: 2023 Sep 12.