Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Parviz Ayazi Shamlou"'
Autor:
Gerard M. Kelly, Parviz Ayazi Shamlou, Amareth Lim, Angelia Reed-Bogan, Peter K. Lambooy, Lawrence H. Breen, Brandon Doyle
Publikováno v:
Biotechnology Progress. 34:120-129
During purification process development of a recombinant therapeutic protein, an endoproteolytic activity endogenous to the Chinese hamster ovary (CHO) cells and leading to degradation at particular hydrophobic amino acid residues (e.g., Phe and Trp)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::885e4fc56323c607c8a0bd4d8ccb6534
https://doi.org/10.1002/btpr.2530
https://doi.org/10.1002/btpr.2530
Autor:
Dayue Chen, Kurt Brorson, Rakhi B. Shah, Erik K. Read, Daniel Strauss, Adith Venkiteshwaran, Scott Lute, A Kreuzman, George Miesegaes, Parviz Ayazi Shamlou
Publikováno v:
Biotechnology and Bioengineering. 109:2048-2058
Traditionally, post-production culture harvest capture of therapeutic monoclonal antibodies (mAbs) is performed using Protein A chromatography. We investigated the efficiency and robustness of cation exchange chromatography (CEX) in an effort to eval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b3b84a5f99618d8d7be0ada3ad19671
https://doi.org/10.1002/bit.24480
https://doi.org/10.1002/bit.24480
Autor:
Andrew F. Day, Simyee Kong, Nigel J. Titchener-Hooker, Parviz Ayazi Shamlou, Ronan D. O'Kennedy
Publikováno v:
Journal of Chemical Technology & Biotechnology. 84:696-701
BACKGROUND: Viscosity – time plots for plasmid-bearing E. coli cells undergoing alkaline lysis are reported in this study. The plots demonstrate generic features that reflect the progress of fermentation and allow an assessment of the genomic DNA d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de0843c253a99ccd672f9045d8c1515f
https://doi.org/10.1002/jctb.2101
https://doi.org/10.1002/jctb.2101
Autor:
Supti Sarkar, Stephen L. Hart, Michael A. Pilkington-Miksa, S. E. Barker, Helen C. Hailes, Michele J. Writer, Alethea B. Tabor, Parviz Ayazi Shamlou
Publikováno v:
European Journal of Organic Chemistry. 2008:2900-2914
Improving the buffer and serum stability of non-viral gene delivery vectors, and increasing their circulation time in vivo, is an important focus of current research in gene therapy. The most successful strategies to date have involved shielding the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b2be646916ab03492185a1a1e8012ca
https://doi.org/10.1002/ejoc.200701188
https://doi.org/10.1002/ejoc.200701188
Publikováno v:
Biochemical Engineering Journal. 40:138-149
The detailed engineering characterisation of shaken microtitre-plate bioreactors will enhance our understanding of microbial and mammalian cell culture in these geometries and will provide guidance on the scale-up of microwell results to laboratory a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90adb8ee4680f35634e3ae313a340eb3
https://doi.org/10.1016/j.bej.2007.12.005
https://doi.org/10.1016/j.bej.2007.12.005
Autor:
Parviz Ayazi Shamlou, Stephen L. Hart, Michele J. Writer, Helen C. Hailes, Qing-Hai Meng, Supti Sarkar, Suzie E. Barker, Alethea B. Tabor, Michael A. Pilkington-Miksa
Publikováno v:
Bioconjugate Chemistry. 18:1800-1810
We have developed efficient synthetic routes to two hydrophobic amino acids, suitably protected for solid-phase peptide synthesis, and have successfully synthesized peptides containing these or other hydrophobic amino acids as spacers between a Lys16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b7e524a011b02c5156c510d293c1ea
https://doi.org/10.1021/bc0700943
https://doi.org/10.1021/bc0700943
Autor:
Helen C. Hailes, Alethea B. Tabor, John B. Wong, Stephen L. Hart, Parviz Ayazi Shamlou, Michele J. Writer, Christopher A. Hurley, M. Jayne Lawrence, Robin J. McAnulty, Danielle M. Copeman, Marianne Odlyha, Supti Sarkar
Publikováno v:
Journal of Liposome Research. 16:373-389
We have previously described a lipopolyplex formulation comprising a mixture of a cationic peptide with an integrin-targeting motif (K16GACRRETAWACG) and Lipofectin, a liposome consisting of DOTMA and DOPE in a 1:1 ratio. The high transfection effici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c5de88fd814f50c3556dec9e2fa6632
https://doi.org/10.1080/08982100600992500
https://doi.org/10.1080/08982100600992500
Publikováno v:
Trends in Biotechnology. 21:29-37
Microscale processing techniques are rapidly emerging as a means to increase the speed of bioprocess design and reduce material requirements. Automation of these techniques can reduce labour intensity and enable a wider range of process variables to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c185a64d47f81ec3b6a038db5901dc
https://doi.org/10.1016/s0167-7799(02)00011-2
https://doi.org/10.1016/s0167-7799(02)00011-2
Publikováno v:
JOURNAL OF CHEMICAL ENGINEERING OF JAPAN. 34:640-646
A novel ultra high velocity jet device was used to form fine drops of an organic phase in a continuous aqueous stream. Experiments were carried out for different operating conditions including number of passes through the orifice and pressure drops a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02d031a4b721ff3b9ee123e6eaacc0e8
https://doi.org/10.1252/jcej.34.640
https://doi.org/10.1252/jcej.34.640