Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Parvaz Madadi"'
Autor:
Parvaz Madadi, Johanna Sistonen, Gregory Silverman, Rebecca Gladdy, Colin J Ross, Bruce C Carleton, Jose C Carvalho, Michael R Hayden, Gideon Koren
Publikováno v:
Pain Research and Management, Vol 18, Iss 3, Pp 133-136 (2013)
BACKGROUND: Systemic approaches are needed to understand how variations in the genes associated with opioid pharmacokinetics and response can be used to predict patient outcome. The application of pharmacogenetic analysis to two cases of life-threate
Externí odkaz:
https://doaj.org/article/0acaa1ee33b047b58f4731ee7fa292f5
Autor:
Emily Groot, Fiona G Kouyoumdjian, Lori Kiefer, Parvaz Madadi, Jeremy Gross, Brittany Prevost, Reuven Jhirad, Dirk Huyer, Victoria Snowdon, Navindra Persaud
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0157512 (2016)
BACKGROUND:There is an increased risk of death due to drug toxicity after release from incarceration. The purpose of this study was to describe the timing, rate and circumstances of drug toxicity deaths following release from incarceration. This info
Externí odkaz:
https://doaj.org/article/318a74d8f7a3437c8b07859cc725d344
Autor:
Lauren E Kelly, Shahnaz A Chaudhry, Michael J Rieder, Geert 't Jong, Myla E Moretti, Andrea Lausman, Colin Ross, Howard Berger, Bruce Carleton, Michael R Hayden, Parvaz Madadi, Gideon Koren
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e70073 (2013)
Neonates are commonly exposed to maternal codeine through breast milk. Central Nervous System (CNS) depression has been reported in up to 24% of nurslings following codeine exposure. In 2009, we developed guidelines to improve the safety of codeine u
Externí odkaz:
https://doaj.org/article/84f67455762b4678859a875ecda39467
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60600 (2013)
The impact of the prescription opioid public health crisis has been illustrated by the dramatic increase in opioid-related deaths in North America. We aimed to identify patterns and characteristics amongst opioid-users whose cause of death was relate
Externí odkaz:
https://doaj.org/article/b86e65bf43ac4301b73a2dd3f2a3a8c8
Publikováno v:
Journal of Public Health in Africa, Vol 3, Iss 2 (2012)
Few studies have systematically characterized drug-prescribing patterns, particularly at the primary care level in Nigeria, a country disproportionately burdened with disease. The aim of this study was to assess the disease profiles and drug-prescrib
Externí odkaz:
https://doaj.org/article/f5560a8a3164467e8db8338bd9e48ede
Autor:
Parvaz Madadi
Publikováno v:
Pediatric Drugs. 17:91-95
Children represent a special population characterized by dynamic changes which may affect drug safety and efficacy. The interplay of pharmacogenetics with physiological alterations that occur throughout development is an area of increasing research f
Publikováno v:
Annual Review of Pharmacology and Toxicology. 54:295-315
Pregnant women are almost always excluded from randomized controlled clinical trials, as the risks to the fetus posed by most new chemical entities or approved drugs cannot be sufficiently ruled out. Hence, a major scientific challenge in this field
Autor:
Anders Helldén, Parvaz Madadi
Publikováno v:
Pharmacogenomics. 14:1779-1791
It is well-known that profound physiological and biochemical changes occur throughout the course of pregnancy. At the same time, the role of pharmacogenomics in modulating the metabolism and response profile to numerous medications has been elucidate
Autor:
Colin J. D. Ross, Bruce Carleton, Parvaz Madadi, Gideon Koren, Michael R. Hayden, Ilan Matok, Lauren E. Kelly, Jessica Lam
Publikováno v:
Therapeutic Drug Monitoring. 35:466-472
OBJECTIVE: To assess the effect of maternal CYP2D6, CYP3A5, ABCB1, and OPRM1 polymorphisms in predicting both neonatal and maternal central nervous system depression after oxycodone use during lactation. STUDY DESIGN: A nested case-control study in 6
Publikováno v:
Expert Review of Molecular Diagnostics. 12:831-840
A new wave of rapid and accurate molecular diagnostics, which harness the power of genomics and proteomics, hold great potential to improve aspects of maternal health on a global scale. This review will provide a context to issues related to global m