Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Parvathi Haridas"'
Publikováno v:
PeerJ, Vol 5, p e3754 (2017)
Background Standard two-dimensional (2D) cell migration assays do not provide information about vertical invasion processes, which are critical for melanoma progression. We provide information about three-dimensional (3D) melanoma cell migration, pro
Externí odkaz:
https://doaj.org/article/fcb762903211417ab8f2e14a91a5f1c6
Autor:
Rachelle N. Binny, Parvathi Haridas, Alex James, Richard Law, Matthew J. Simpson, Michael J. Plank
Publikováno v:
PeerJ, Vol 4, p e1689 (2016)
Mathematical models of collective cell movement often neglect the effects of spatial structure, such as clustering, on the population dynamics. Typically, they assume that individuals interact with one another in proportion to their average density (
Externí odkaz:
https://doaj.org/article/83748783b2294243b4c3d3a8b2cd1b11
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85488 (2014)
Most mathematical models of collective cell spreading make the standard assumption that the cell diffusivity and cell proliferation rate are constants that do not vary across the cell population. Here we present a combined experimental and mathematic
Externí odkaz:
https://doaj.org/article/cf1d655838374989b939ea56223e471b
Autor:
D. L. Sean McElwain, Alexander P Browning, Jacqui A. McGovern, Parvathi Haridas, Matthew J. Simpson
Publikováno v:
BMC Systems Biology, Vol 12, Iss 1, Pp 1-15 (2018)
BMC Systems Biology
BMC Systems Biology
BackgroundMelanoma can be diagnosed by identifying nests of cells on the skin surface. Understanding the processes that drive nest formation is important as these processes could be potential targets for new cancer drugs. Cell proliferation and cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77568ca205321bd228520ce5af3d579b
http://link.springer.com/article/10.1186/s12918-018-0559-9
http://link.springer.com/article/10.1186/s12918-018-0559-9
Autor:
Nicole Bartnikowski, Shaun D. Gregory, Eleonore C.L. Bolle, Tony J. Parker, John F. Fraser, Parvathi Haridas, Tim R. Dargaville
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials
The interface between synthetic percutaneous devices and skin is a common area for bacterial infection, which may ultimately result in failure of the device. Better integration of percutaneous devices with skin may help reduce infection rates due to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07c37f9298d83b363d112836b599a39a
https://pubmed.ncbi.nlm.nih.gov/31169980
https://pubmed.ncbi.nlm.nih.gov/31169980
Autor:
D. L. Sean McElwain, Joshua V. Ross, Benjamin J. Binder, Parvathi Haridas, Stuart T. Johnston, Matthew J. Simpson
Publikováno v:
Journal of Theoretical Biology. 400:19-31
Scratch assays are often used to investigate potential drug treatments for chronic wounds and cancer. Interpreting these experiments with a mathematical model allows us to estimate the cell diffusivity, D, and the cell proliferation rate, λ. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::299f61a711834e4c578ee5fc6af03f51
https://doi.org/10.1016/j.jtbi.2016.04.012
https://doi.org/10.1016/j.jtbi.2016.04.012
Publikováno v:
Bulletin of mathematical biology. 81(3)
We present a novel framework to parameterise a mathematical model of cell invasion that describes how a population of melanoma cells invades into human skin tissue. Using simple experimental data extracted from complex experimental images, we estimat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27d16c36ca606eb1bbf6da26184e4e8b
https://pubmed.ncbi.nlm.nih.gov/30443704
https://pubmed.ncbi.nlm.nih.gov/30443704
Publikováno v:
PeerJ, Vol 5, p e3754 (2017)
PeerJ
PeerJ
BackgroundStandard two-dimensional (2D) cell migration assays do not provide information about vertical invasion processes, which are critical for melanoma progression. We provide information about three-dimensional (3D) melanoma cell migration, prol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd21c54e4cc373de5816b97d74bfdb93
Autor:
Parvathi Haridas, Jacqui A. McGovern, Catherine J. Penington, D. L. Sean McElwain, Matthew J. Simpson
Malignant spreading involves the migration of cancer cells amongst other native cell types. For example, in vivo melanoma invasion involves individual melanoma cells migrating through native skin, which is composed of several distinct subpopulations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbaa27c3284c8afca862594183c6b17b