Výsledky vyhledávání - "Parul Khajuria"

Akademický článek

Flurbiprofen inhibits heme induced NLRP3 inflammasome in Berkeley sickle cell disease mice

Autor: Dilpreet Kour, Mehboob Ali, Parul Khajuria, Kuhu Sharma, Palash Ghosh, Sukhleen Kaur, Surbhi Mahajan, P. Ramajayan, Sonali S. Bharate, Subhash Bhardwaj, Sanghapal D. Sawant, D. Srinivasa Reddy, Ajay Kumar

Publikováno v: Frontiers in Pharmacology, Vol 14 (2023)

Sickle cell disease (SCD) is accompanied by several complications, which emanate from the sickling of erythrocytes due to a point mutation in the β-globin chain of hemoglobin. Sickled erythrocytes are unable to move smoothly through small blood capi

Externí odkaz: https://doaj.org/article/054a2f6f7e1f498b9b0cb539a2c7558e

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Molecular mechanism for the involvement of CYP2E1/NF-κB axis in bedaquiline-induced hepatotoxicity

Autor: Pankul Kotwal, Parul Khajuria, Sumit Dhiman, Dilpreet Kour, Shakti Kumar Dhiman, Ajay Kumar, Utpal Nandi

Publikováno v: Life sciences.

Bedaquiline (BDQ) is a new class of anti-tubercular (anti-TB) drugs and is currently reserved for multiple drug resistance (MDR-TB). However, after receiving fast-track approval, its clinical studies demonstrate that its treatment is associated with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c0aaa14f19d498cceece4fde53d5145
https://pubmed.ncbi.nlm.nih.gov/36621541

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Tetramethoxystilbene Inhibits NLRP3 Inflammasome Assembly via Blocking the Oligomerization of Apoptosis-Associated Speck-like Protein Containing Caspase Recruitment Domain: In Vitro and In Vivo Evaluation

Autor: Ajay Kumar, Parul Khajuria, Mehboob Ali, Mohd Abdullaha, Ramesh Mudududdla, Dilpreet Kour, Sandip B. Bharate

Publikováno v: ACS Pharmacology & Translational Science. 4:1437-1448

Nucleotide-binding domain leucine-rich repeat family pyrin domain containing 3 (NLRP3) inflammasome complex regulates the caspase-1 activity and subsequent processing of interleukin-1β (IL-1β). Various inflammatory diseases involve the activation o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::220e2b121064463627bcbda510cab544
https://doi.org/10.1021/acsptsci.1c00126

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Tetramethoxystilbene Inhibits NLRP3 Inflammasome Assembly via Blocking the Oligomerization of Apoptosis-Associated Speck-like Protein Containing Caspase Recruitment Domain

Autor: Mohd, Abdullaha, Mehboob, Ali, Dilpreet, Kour, Ramesh, Mudududdla, Parul, Khajuria, Ajay, Kumar, Sandip B, Bharate

Publikováno v: ACS Pharmacol Transl Sci

[Image: see text] Nucleotide-binding domain leucine-rich repeat family pyrin domain containing 3 (NLRP3) inflammasome complex regulates the caspase-1 activity and subsequent processing of interleukin-1β (IL-1β). Various inflammatory diseases involv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b4d4850fb29611482aeb56c9ce5dee13
https://pubmed.ncbi.nlm.nih.gov/34423275

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