Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Paru P. Kathpalia"'
1
Prostaglandin E2 induces chloride secretion through crosstalk between cAMP and calcium signaling in mouse inner medullary collecting duct cells
Autor: Alan C. Pao, Madhumitha Rajagopal, Yu Chen, Paru P. Kathpalia, Sheela V. Thomas
Publikováno v: American Journal of Physiology-Cell Physiology. 306:C263-C278
Under conditions of high dietary salt intake, prostaglandin E2 (PGE2) production is increased in the collecting duct and promotes urinary sodium chloride (NaCl) excretion; however, the molecular mechanisms by which PGE2 increases NaCl excretion in th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1df3f7b45aa8383f98e2dc150bd77478
https://doi.org/10.1152/ajpcell.00381.2012
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2
SGK1 regulation by miR-466g in cortical collecting duct cells
Autor: Mollie E. Jacobs, Yu Chen, Paru P. Kathpalia, Alan C. Pao, Emily J. Noonan, Sheela V. Thomas
Publikováno v: American journal of physiology. Renal physiology. 310(11)
Micro-RNAs (miRNAs) are noncoding RNAs that bind target mRNA transcripts and modulate gene expression. In the cortical collecting duct (CCD), aldosterone stimulates the expression of genes that increase activity of the epithelial sodium channel (ENaC
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6fa06326204dd5755f59c0a7843a315
https://pubmed.ncbi.nlm.nih.gov/26911843
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3
Activation of P2Y1 and P2Y2 receptors induces chloride secretion via calcium-activated chloride channels in kidney inner medullary collecting duct cells
Autor: Madhumitha Rajagopal, Paru P. Kathpalia, Alan C. Pao, Sheela V. Thomas
Publikováno v: American Journal of Physiology-Renal Physiology. 301:F544-F553
Dysregulation of urinary sodium chloride (NaCl) excretion can result in extracellular fluid (ECF) volume expansion and hypertension. Recent studies demonstrated that urinary nucleotide excretion increases in mice ingesting a high-salt diet and that t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d452411a777b5b20a521b2eaf431fbb
https://doi.org/10.1152/ajprenal.00709.2010
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4
Epithelial Sodium Channel Regulation by Cell Surface-associated Serum- and Glucocorticoid-regulated Kinase 1
Autor: Carol Charlton, Paru P. Kathpalia, Madhumitha Rajagopal, Douglas C. Eaton, Alan C. Pao, My N. Helms, Jianning Zhang, Sheela V. Thomas
Publikováno v: Journal of Biological Chemistry. 286:32074-32085
Serum- and glucocorticoid-regulated kinase 1 (sgk1) participates in diverse biological processes, including cell growth, apoptosis, and sodium homeostasis. In the cortical collecting duct of the kidney, sgk1 regulates sodium transport by stimulating
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::666965300693f11db07395325a3ed023
https://doi.org/10.1074/jbc.m111.278283
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5
The natriuretic mechanism of Gamma-Melanocyte-Stimulating Hormone
Autor: Carol Charlton, Paru P. Kathpalia, Madhumitha Rajagopal, Alan C. Pao
Publikováno v: Peptides. 32:1068-1072
Gamma-Melanocyte Stimulating Hormone (Gamma-MSH) regulates sodium (Na(+)) balance and blood pressure through activation of the melanocortin receptor 3 (MC3-R). The mechanism of the natriuretic effect is proposed to involve binding of MC3-R either in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d9bf7405c2cbb1a614cca022c7cb795
https://doi.org/10.1016/j.peptides.2011.02.006
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6
Mechanism and function of high vitamin D receptor levels in genetic hypercalciuric stone-forming rats
Autor: Gert-Jan C. M. Van Den Bemd, Johannes P.T.M. van Leeuwen, Hector F. DeLuca, Paru P. Kathpalia, David A. Bushinsky, Alexander J. Karnauskas, Murray J. Favus
Publikováno v: Journal of Bone and Mineral Research, 20(3), 447-454. Wiley-Blackwell
UNLABELLED The functional status and mechanism of increased VDR in GHS rats were investigated. Basal VDR and calbindins were increased in GHS rats. 1,25(OH)(2)D(3) increased VDR and calbindins in controls but not GHS rats. VDR half-life was prolonged
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::121a3dd38980bf7201a567ad014ae883
https://doi.org/10.1359/jbmr.041120
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7
Hyperresponsiveness of vitamin D receptor gene expression to 1,25-dihydroxyvitamin D3. A new characteristic of genetic hypercalciuric stone-forming rats
Autor: David A. Bushinsky, Murray J. Favus, Paru P. Kathpalia, Jianling Yao
Publikováno v: Journal of Clinical Investigation. 101:2223-2232
Hypercalciuria in genetic hypercalciuric stone-forming (GHS) rats is accompanied by intestinal Ca hyperabsorption with normal serum 1,25-dihydroxyvitamin D 3 (1,25(OH) 2 D 3 ) lev- els, elevation of intestinal, kidney, and bone vitamin D re- ceptor (
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af81b3df261c6a120307da818b34ee2b
https://doi.org/10.1172/jci1164
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8
Differential effects of extracellular ATP on chloride transport in cortical collecting duct cells
Autor: Paru P. Kathpalia, Madhumitha Rajagopal, Alan C. Pao, Jonathan Widdicombe
Extracellular ATP in the cortical collecting duct can inhibit epithelial sodium channels (ENaC) but also stimulate calcium-activated chloride channels (CACC). The relationship between ATP-mediated regulation of ENaC and CACC activity in cortical coll
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36c7e7f6f5540d15a4865dfc7434dc67
https://europepmc.org/articles/PMC3423110/
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