Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Paru B. Oatey"'
1
Lighting up insulin action
Autor: Paru B. Oatey, LM Tyas, Gavin I. Welsh, LM Fletcher, James G. Wakefield, Jeremy M. Tavaré
Publikováno v: Diabetic Medicine. 18:253-260
Understanding the mechanism of insulin action remains one of the most important challenges in modern medical biology. Recent advances in cell imaging techniques, increased processing power of computers and the internet, and the introduction of novel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dd185089961610bd5a56e08f4cbab6cd
https://doi.org/10.1046/j.1464-5491.2001.00540.x
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2
Role for the microtubule cytoskeleton in GLUT4 vesicle trafficking and in the regulation of insulin-stimulated glucose uptake
Autor: Gavin I. Welsh, LM Fletcher, Paru B. Oatey, Jeremy M. Tavaré
Publikováno v: Biochemical Journal. 352:267-276
Insulin stimulates glucose uptake into adipocytes by promoting the translocation of the glucose transporter isoform 4 (GLUT4) from intracellular vesicles to the plasma membrane. In 3T3-L1 adipocytes GLUT4 resides both in an endosomal pool, together w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f0fa37db686ce52ce5cd61d8d5eed478
https://doi.org/10.1042/bj3520267
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3
Confocal imaging of the subcellular distribution of phosphatidylinositol 3,4,5-trisphosphate in insulin- and PDGF-stimulated 3T3-L1 adipocytes
Autor: Kanamarlapudi Venkateswarlu, Jeremy M. Tavaré, Emily J. Foulstone, Paru B. Oatey, Peter J. Cullen, Alan G. Williams, LM Fletcher
Publikováno v: Biochemical Journal. 344:511-518
The activation of phosphatidylinositol 3-kinase (PI 3-kinase) and production of PtdIns(3,4,5)P3 is crucial in the actions of numerous extracellular stimuli, including insulin-stimulated glucose uptake. Platelet-derived growth factor (PDGF) also stimu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d73a4aa1d2576a0f23757d420e3d73b0
https://doi.org/10.1042/bj3440511
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4
Protein Kinase B Stimulates the Translocation of GLUT4 but Not GLUT1 or Transferrin Receptors in 3T3-L1 Adipocytes by a Pathway Involving SNAP-23, Synaptobrevin-2, and/or Cellubrevin
Autor: LM Fletcher, Paru B. Oatey, J. Oliver Dolly, Patrick G. Foran, Jeremy M. Tavaré, Nadiem Mohammed
Publikováno v: Journal of Biological Chemistry. 274:28087-28095
An interaction of SNAP-23 and syntaxin 4 on the plasma membrane with vesicle-associated synaptobrevin-2 and/or cellubrevin, known as SNAP (soluble N -ethyl-maleimide-sensitive factorattachment protein) receptors or SNAREs, has been proposed to provid
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::323cf06142e3b00122aa6cc4a8a3f961
https://doi.org/10.1074/jbc.274.40.28087
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6
Inhibition of alanine:glyoxylate aminotransferase 1 dimerization is a prerequisite for its peroxisome-to-mitochondrion mistargeting in primary hyperoxaluria type 1
Autor: Christopher J. Danpure, James Leiper, Paru B. Oatey
Publikováno v: The Journal of Cell Biology
Peroxisome-to-mitochondrion mistargeting of the homodimeric enzyme alanine:glyoxylate aminotransferase 1 (AGT) in the autosomal recessive disease primary hyperoxaluria type 1 (PH1) is associated with the combined presence of a normally occurring Pro(
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f27ffe7250894f1f05e5f7502e933768
https://doi.org/10.1083/jcb.135.4.939
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