Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Partho Ghosh"'
Autor:
Atanu Maiti, Cosmo Z. Buffalo, Saumya Saurabh, Felipe Montecinos-Franjola, Justin S. Hachey, William J. Conlon, Geraldine N. Tran, Bakar Hassan, Kylie J. Walters, Mikhail Drobizhev, W. E. Moerner, Partho Ghosh, Hiroshi Matsuo, Roger Y. Tsien, John Y. Lin, Erik A. Rodriguez
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract The small Ultra-Red Fluorescent Protein (smURFP) represents a new class of fluorescent protein with exceptional photostability and brightness derived from allophycocyanin in a previous directed evolution. Here, we report the smURFP crystal s
Externí odkaz:
https://doaj.org/article/c7b97c5ea32a4f34823ce6ae4a9c9f7e
Autor:
Lindsey Spiegelman, Adrian Bahn-Suh, Elizabeth T Montaño, Ling Zhang, Greg L Hura, Kathryn A Patras, Amit Kumar, F Akif Tezcan, Victor Nizet, Susan E Tsutakawa, Partho Ghosh
Publikováno v:
PLoS Pathogens, Vol 18, Iss 9, p e1010829 (2022)
Multidrug-resistant (MDR) Enterococcus faecalis are major causes of hospital-acquired infections. Numerous clinical strains of E. faecalis harbor a large pathogenicity island that encodes enterococcal surface protein (Esp), which is suggested to prom
Externí odkaz:
https://doaj.org/article/6211ff82813b4dc687149646b2ae16f0
Publikováno v:
eLife, Vol 11 (2022)
Surface-associated, coiled-coil M proteins of Streptococcus pyogenes (Strep A) disable human immunity through interaction with select proteins. However, coiled coils lack features typical of protein–protein interaction sites, and it is therefore ch
Externí odkaz:
https://doaj.org/article/c6004c79d0594558a36fb14223475b8d
Autor:
Jori O Mills, Partho Ghosh
Publikováno v:
PLoS Pathogens, Vol 17, Iss 2, p e1009248 (2021)
M and M-like proteins are major virulence factors of the widespread and potentially deadly bacterial pathogen Streptococcus pyogenes. These proteins confer resistance against innate and adaptive immune responses by recruiting specific human proteins
Externí odkaz:
https://doaj.org/article/ca231fa063bf464f9bb7ce6c57c7e84d
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0205618 (2019)
Diversity-generating retroelements (DGRs) are widely distributed in bacteria, archaea, and microbial viruses, and bring about unparalleled levels of sequence variation in target proteins. While DGR variable proteins share low sequence identity, the s
Externí odkaz:
https://doaj.org/article/6e867c4e17864f99a200468396e71cd9
Autor:
Brent Y Hamaoka, Partho Ghosh
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114685 (2014)
Host cell traversal by Plasmodium, the protozoan cause of malaria, is an essential part of this parasite's virulence. In this process, the parasite enters a host cell through a parasite-induced pore, traverses the host cell, and then exits the host c
Externí odkaz:
https://doaj.org/article/5f33556b49d0422b8ee5931e95ee56b6
Autor:
Cheng-Yuan Kao, Ferdinand C O Los, Danielle L Huffman, Shinichiro Wachi, Nicole Kloft, Matthias Husmann, Valbona Karabrahimi, Jean-Louis Schwartz, Audrey Bellier, Christine Ha, Youn Sagong, Hui Fan, Partho Ghosh, Mindy Hsieh, Chih-Shen Hsu, Li Chen, Raffi V Aroian
Publikováno v:
PLoS Pathogens, Vol 7, Iss 3, p e1001314 (2011)
Here we present the first global functional analysis of cellular responses to pore-forming toxins (PFTs). PFTs are uniquely important bacterial virulence factors, comprising the single largest class of bacterial protein toxins and being important for
Externí odkaz:
https://doaj.org/article/33afd7ffdcaa4c2b8670aa81a8cc9d3c
Publikováno v:
PLoS Pathogens, Vol 6, Iss 5, p e1000900 (2010)
Listeria monocytogenes (Lm) uses InlA to invade the tips of the intestinal villi, a location at which cell extrusion generates a transient defect in epithelial polarity that exposes the receptor for InlA, E-cadherin, on the cell surface. As the dying
Externí odkaz:
https://doaj.org/article/217e6a10b1ae4974b5886a674a876da9
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8364 (2009)
The down-regulation of the major histocompatibility complex class I (MHC-I) from the surface of infected cells by the Nef proteins of primate immunodeficiency viruses likely contributes to pathogenesis by providing evasion of cell-mediated immunity.
Externí odkaz:
https://doaj.org/article/1c07314777174b8586e37ea3845fc7ff
Publikováno v:
PLoS Biology, Vol 6, Iss 6, p e131 (2008)
Diversity-generating retroelements (DGRs) recognize novel ligands through massive protein sequence variation, a property shared uniquely with the adaptive immune response. Little is known about how recognition is achieved by DGR variable proteins. He
Externí odkaz:
https://doaj.org/article/1705d6f2babb4c68b4ef80c4f69442e3