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Human IgG1 antibodies suppress angiogenesis in a target-independent manner

Autor: Tetsuhiro Yasuma, Hiroko Terasaki, Mike Clark, Valeria Cicatiello, Laura Tudisco, Yuichiro Ogura, Wallace Y. Langdon, Judit Z. Baffi, Miho Nozaki, Pierre Bruhns, Younghee Kim, Parthasarathy Arpitha, Sasha Bogdanovich, Nagaraj Kerur, Takeshi Mizutani, Yoshio Hirano, Bradley D. Gelfand, Benjamin J. Fowler, Balamurali K. Ambati, Ivana Apicella, Kathryn L. Armour, Shengjian Li, Sandro De Falco, Ryo Ijima, Hiroki Kaneko, Ana Bastos-Carvalho, Valeria Tarallo, Jeanette H. W. Leusen, Charles B. Wright, Jayakrishna Ambati, J. Sjef Verbeek, Arturo Brunetti, Reo Yasuma, Annamaria Sandomenico, Adelaide Greco, Menotti Ruvo

Publikováno v: Signal Transduction and Targeted Therapy, 1. NATURE PUBLISHING GROUP
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy, Nature.com, 2016, 1, pp.15001. ⟨10.1038/sigtrans.2015.1⟩
Signal Transduction and Targeted Therapy, 2016, 1, pp.15001. ⟨10.1038/sigtrans.2015.1⟩
Signal Transduction and Targeted Therapy ( 1 (2016): 15001. doi:10.1038/sigtrans.2015.1
info:cnr-pdr/source/autori:Bogdanovich, Sasha; Kim, Younghee; Mizutani, Takeshi; Yasuma, Reo; Tudisco, Laura; Cicatiello, Valeria; Bastos-Carvalho, Ana; Kerur, Nagaraj; Hirano, Yoshio; Baffi, Judit Z; Tarallo, Valeria; Li, Shengjian; Yasuma, Tetsuhiro; Arpitha, Parthasarathy; Fowler, Benjamin J; Wright, Charles B; Apicella, Ivana; Greco, Adelaide; Brunetti, Arturo; Ruvo, Menotti; Sandomenico, Annamaria; Nozaki, Miho; Ijima, Ryo; Kaneko, Hiroki; Ogura, Yuichiro; Terasaki, Hiroko; Ambati, Balamurali K; Leusen, Jeanette Hw; Langdon, Wallace Y; Clark, Michael R; Armour, Kathryn L; Bruhns, Pierre; Verbeek, J Sjef; Gelfand, Bradley D; De Falco, Sandro; Ambati, Jayakrishna/titolo:Human IgG1 antibodies suppress angiogenesis in a target-independent manner./doi:10.1038%2Fsigtrans.2015.1/rivista:Signal Transduction and Targeted Therapy (/anno:2016/pagina_da:15001/pagina_a:/intervallo_pagine:15001/volume:1
Signal transduction and targeted therapy, 1. Springer Nature

Aberrant angiogenesis is implicated in diseases affecting nearly 10% of the world’s population. The most widely used anti-angiogenic drug is bevacizumab, a humanized IgG1 monoclonal antibody that targets human VEGFA. Although bevacizumab does not r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a748982605123f93b3715b7cbf03313
http://hdl.handle.net/11588/636288

http://www.omicsgroup.org/journals/high-density-lipoproteinsnatures-endogenous-nanovehicles-are-pushing-alzheimers-drug-discovery-to-new-frontiers-2168-9296-1000e133.php?aid=59111

Autor: Parthasarathy Arpitha

Publikováno v: Cell & Developmental Biology.

Although several cellular and immune based therapies are available, cold atmospheric plasma (CAP) is gaining importance due to its functional ability to accelerate and promote apoptosis of tumour cells. The ionized jet of plasma has been shown to sel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6c01e982a0a6036e70755c33cc35b788
https://doi.org/10.4172/2168-9296.1000151

Adult human buccal epithelial stem cells: identification, ex-vivo expansion, and transplantation for corneal surface reconstruction

Autor: C G Priya, K Sheetal, Namperumalsamy Venkatesh Prajna, K Usha, Parthasarathy Arpitha, S Vaishali, Veerappan Muthukkaruppan

Publikováno v: Eye (London, England). 25(12)

To identify adult human buccal epithelial stem cells (SCs) on the basis of two parameters (high p63 expression and greater nucleus/cytoplasmic (N/C) ratio) and to evaluate clinical efficacy of ex-vivoexpanded autologous epithelium in bilateral limbal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b71d22d2cfa41ab94909f3d83ab22c6d
https://pubmed.ncbi.nlm.nih.gov/21941360

High expression of p63 combined with a large N/C ratio defines a subset of human limbal epithelial cells: implications on epithelial stem cells

Autor: Namperumalsamy Venkatesh Prajna, Muthiah Srinivasan, Veerappan Muthukkaruppan, Parthasarathy Arpitha

Publikováno v: Investigative ophthalmologyvisual science. 46(10)

PURPOSE. To characterize human limbal epithelial cells based on the expression levels of nuclear protein p63 and the nucleus-to-cytoplasm (N/C) ratio. METHODS. Limbal, peripheral, and central corneal epithelia were separated from the stroma by Dispas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40367abc6ef6579306b8b0db4b8d2aea
https://pubmed.ncbi.nlm.nih.gov/16186343