Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Partha P. Chakrabarti"'
Autor:
Farhana Hoque, Subhendu Adhikari, Rathindra Nath Mandal, Ajmal Hussan, Debnarayan Chattopadhyay, Baidya Nath Paul, Arabinda Das, Partha Pratim Chakrabarti, Saroj Kumar Swain
Publikováno v:
Exploratory Animal and Medical Research, Vol 12, Iss 2, Pp 195-204 (2022)
The present study depicts the disease incidences in the aqua farms of Moyna, West Bengal, India, during 2018- 2020 and aqua-drugs used by farmers to combat diseases. A total of 132 fish disease incidences were reported, among which parasitic diseas
Externí odkaz:
https://doaj.org/article/1b774ff2b9954f7a8005dc5426c17557
Autor:
Baidya Nath Paul, Debnarayan Chowdhury, Arabinda Das, Rathindra Nath Mandal, Puja Singh, Subhendu Adhikari, Partha Pratim Chakrabarti, Shiba Sankar Giri, Koushik Ghosh
Publikováno v:
Acta Ichthyologica et Piscatoria, Vol 51, Iss 3, Pp 289-298 (2021)
The Indian butter catfish, Ompok bimaculatus (Bloch, 1794), is a high-value catfish that has gained immense consumer preference in South-East Asia. However, information on the nutritional requirements of this species is scanty. Hence, an experiment w
Externí odkaz:
https://doaj.org/article/891b7909f84548f693cdec25f4f68e28
Publikováno v:
Dreaming. 32:135-162
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f61d69cad1988dfe4884dda28763437
https://doi.org/10.1037/drm0000208
https://doi.org/10.1037/drm0000208
Publikováno v:
2022 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops (CVPRW).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::037b85cb913c0d3cadcbb943d7757af7
https://doi.org/10.1109/cvprw56347.2022.00404
https://doi.org/10.1109/cvprw56347.2022.00404
Autor:
David Powers, Guo-Qiang Cao, Scott Middleton, Lisa Sherman, Kelvin Sham, Dawei Zhang, Partha P. Chakrabarti, Faye Hsieh, Andrew Tasker, Yanyan Tudor, Bradley Henkle, Shimin Xu, Lu Min Wong, Ryan Wurz, Liping H. Pettus, Matthew R. Lee, Robert M. Rzasa, Violeta Yu, Christiaan J. M. Saris, Matthew H. Plant, Rashid Syed
Publikováno v:
Journal of Medicinal Chemistry. 51:6280-6292
The p38 mitogen-activated protein kinase (MAPK) is a central signaling molecule in many proinflammatory pathways, regulating the cellular response to a multitude of external stimuli including heat, ultraviolet radiation, osmotic shock, and a variety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7087b9c4f5722d23b003b38ab86133ff
https://doi.org/10.1021/jm8005405
https://doi.org/10.1021/jm8005405
Autor:
Mqhele Ncube, Lillian Liao, Rami Tamir, Yunxin Bo, Narender R. Gavva, James J. S. Treanor, Partha P. Chakrabarti, Markian Stec, Nuria A. Tamayo, Mark H. Norman
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:5118-5122
Clinical candidate AMG 517 (1) is a potent antagonist toward multiple modes of activation of TRPV1; however, it suffers from poor solubility. Analogs with various substituents at the R region of 3 were prepared to improve the solubility while maintai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15df16ed448a11ca22b2d95e3c1e3dc3
https://doi.org/10.1016/j.bmcl.2008.07.112
https://doi.org/10.1016/j.bmcl.2008.07.112
Autor:
Kelvin Sham, Vivian S. W. Li, Liping H. Pettus, Ryan Wurz, David Grosfeld, Andreas Reichelt, Brad Herberich, Guo-Qiang Cao, Partha P. Chakrabarti, Lu Min Wong, Lisa Sherman, Maya C. Thaman, Andrew Tasker, Faye Hsieh, Shimin Xu, Dawei Zhang, Bradley Henkle, James R. Falsey, Matthew R. Lee, Matthew H. Plant, Scot Middleton, Robert M. Rzasa, Anthony B. Reed, Rashid Syed
Publikováno v:
Journal of medicinal chemistry. 51(20)
Investigations into the structure-activity relationships (SAR) of a series of phthalazine-based inhibitors of p38 are described. These efforts originated from quinazoline 1 and through rational design led to the development of a series of orally bioa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4472ff7afe3b7f856819b7fe8180af1c
https://pubmed.ncbi.nlm.nih.gov/18817365
https://pubmed.ncbi.nlm.nih.gov/18817365
Autor:
Partha P. Chakrabarti, Xianghong Wang, Narender R. Gavva, Hongyu Liao, Mark H. Norman, Nuria A. Tamayo, Dan Retz, Anthony W. Bannon, Elizabeth M. Doherty, Markian Stec, Sekhar Surapaneni, Rami Tamir
Publikováno v:
Journal of medicinal chemistry. 51(9)
Transient receptor potential vanilloid 1 (TRPV1) channel antagonists may have clinical utility for the treatment of chronic nociceptive and neuropathic pain. We recently advanced a TRPV1 antagonist, 3 (AMG 517), into clinical trials as a new therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40c3d2fe206f2a9d600977d27d0431b
https://pubmed.ncbi.nlm.nih.gov/18386885
https://pubmed.ncbi.nlm.nih.gov/18386885
Autor:
Liping H. Pettus, Vassil I. Ognyanov, James J. S. Treanor, Phi Tang, Mark H. Norman, Xianghong Wang, Narender R. Gavva, Helming Tan, Rami Tamir, Partha P. Chakrabarti
Publikováno v:
Bioorganicmedicinal chemistry letters. 17(23)
A series of trisubstituted pyrimidines were synthesized to improve aqueous solubility of our first TRPV1 clinical candidate (1; AMG 517), while maintaining potent TRPV1 inhibitory activity. Structure–activity and structure–solubility studies led
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38960115873ad338c2f59a2cdf4584f4
https://pubmed.ncbi.nlm.nih.gov/17937985
https://pubmed.ncbi.nlm.nih.gov/17937985
Novel vanilloid receptor-1 antagonists: 1. Conformationally restricted analogues of trans-cinnamides
Autor:
Thomas Nixey, Rami Tamir, Narender R. Gavva, Mark H. Norman, Partha P. Chakrabarti, Robert M. Rzasa, Vellarkad N. Viswanadhan, Yunxin Bo, Ning Chen, Jiawang Zhu, Nobuko Nishimura, James J. S. Treanor, Christopher H. Fotsch, Vassil I. Ognyanov, Sekhar Surapaneni, Elizabeth M. Doherty, Markian Stec
Publikováno v:
Journal of medicinal chemistry. 50(15)
The vanilloid receptor-1 (VR1 or TRPV1) is a member of the transient receptor potential (TRP) family of ion channels and plays a role as an integrator of multiple pain-producing stimuli. From a high-throughput screening assay, measuring calcium uptak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cfb18a5a5bacea5ac1afc790ad57e32
https://pubmed.ncbi.nlm.nih.gov/17585749
https://pubmed.ncbi.nlm.nih.gov/17585749