Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Partha, Chowdhury"'
Autor:
Lauren E. Boucher, Elisabeth Geyer Prinslow, Michael Feldkamp, Fang Yi, Rupesh Nanjunda, Sheng-Jiun Wu, Tun Liu, Eilyn R. Lacy, Steven Jacobs, Natalia Kozlyuk, Brian Del Rosario, Bingyuan Wu, Patricia Aquino, Robert C. Davidson, Samantha Heyne, Nicholas Mazzanti, James Testa, Michael D. Diem, Elsa Gorre, Andrew Mahan, Hirsh Nanda, Harsha P. Gunawardena, Alexis Gervais, Anthony A. Armstrong, Alexey Teplyakov, Chichi Huang, Adam Zwolak, Partha Chowdhury, Wan Cheung Cheung, Jinquan Luo
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTSingle-chain fragment variable (scFv) domains play an important role in antibody-based therapeutic modalities, such as bispecifics, multispecifics and chimeric antigen receptor T cells or natural killer cells. However, scFv domains exhibit lo
Externí odkaz:
https://doaj.org/article/07a49e5767d741f0bc24b50e3af689e1
Autor:
Adam Zwolak, Szeman Ruby Chan, Paul Harvilla, Sally Mahady, Anthony A. Armstrong, Leopoldo Luistro, Ninkka Tamot, Douglas Yamada, Mehabaw Derebe, Steven Pomerantz, Mark Chiu, Rajkumar Ganesan, Partha Chowdhury
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract TL1A (TNFSF15) is a TNF superfamily ligand which can bind the TNFRSF member death receptor 3 (DR3) on T cells and the soluble decoy receptor DcR3. Engagement of DR3 on CD4+ or CD8+ effector T cells by TL1A induces downstream signaling, leadi
Externí odkaz:
https://doaj.org/article/08da83cacee8430d962876b194440306
Publikováno v:
The Astrophysical Journal, Vol 959, Iss 1, p 16 (2023)
We studied the temporal evolution of quasi-biennial oscillations (QBOs) using acoustic mode oscillation frequencies from the Global Oscillation Network Group. The data used here span more than 25 yr, covering solar cycles 23 and 24 and the ascending
Externí odkaz:
https://doaj.org/article/6eca1a1898ca433d8536f15752c76575
Autor:
Ian White, Ninkka Tamot, Rajitha Doddareddy, Jason Ho, Qun Jiao, Paul B. Harvilla, Tong-Yuan Yang, Brian Geist, M. Jack Borrok, Matthew D. Truppo, Rajkumar Ganesan, Partha Chowdhury, Adam Zwolak
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
The global health crisis and economic tolls of COVID-19 necessitate a panoply of strategies to treat SARS-CoV-2 infection. To date, few treatment options exist, although neutralizing antibodies against the spike glycoprotein have proven to be effecti
Externí odkaz:
https://doaj.org/article/a6460b31f1584b1b94ecaa2b69a6345e
Autor:
Hsiu-Min Pan, Chi-Chi Wu, Chun-Yi Lin, Chao-Shian Hsu, Yi-Chen Tsai, Partha Chowdhury, Chih-Hsing Wang, Kai-Hsin Chang, Chieh-Hsuan Yang, Ming-Ho Liu, Yan-Chang Chen, Shih-Po Su, Yi-Jang Lee, Huihua Kenny Chiang, Yang-Hsiang Chan, Pi-Tai Chou
Publikováno v:
Journal of the American Chemical Society. 145:516-526
Organic molecules having emission in the NIR(II) region are emergent and receiving enormous attention. Unfortunately, attaining accountable organic emission intensity around the NIR(II) region is hampered by the dominant internal conversion operated
Autor:
David A. Tice, Robert E. Hollingsworth, Ronald Herbst, Bahija Jallal, Philipp Steiner, Ping Tsui, Partha Chowdhury, Chunning Yang, Leslie Wetzel, Ray Rothstein, Hong Chen, Ravinder Tammali, Krista Kinneer, Kevin Schifferli, Rosa A. Carrasco, Zhan Xiao
HER3/ERBB3 is a kinase-deficient member of the EGFR family receptor tyrosine kinases (RTK) that is broadly expressed and activated in human cancers. HER3 is a compelling cancer target due to its important role in activation of the oncogenic PI3K/AKT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcc96583b01d461e7fb0468a7a88fa35
https://doi.org/10.1158/1535-7163.c.6538702.v1
https://doi.org/10.1158/1535-7163.c.6538702.v1
Autor:
David A. Tice, Robert E. Hollingsworth, Ronald Herbst, Bahija Jallal, Philipp Steiner, Ping Tsui, Partha Chowdhury, Chunning Yang, Leslie Wetzel, Ray Rothstein, Hong Chen, Ravinder Tammali, Krista Kinneer, Kevin Schifferli, Rosa A. Carrasco, Zhan Xiao
Figure 1: KTN3379 specifically binds to HER3; Figure 2: KTN3379 suppresses cell-growth in HRG-HER3 autocrine cells and HRGinduced VEGF secretion; Figure 3: KTN3379 arrests HER2+ breast cancer cells in G0/G1-phase; Figure 4: KTN3379 is inactive in HER
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39380c21c500de7b31d46a26363070fb
https://doi.org/10.1158/1535-7163.22507480.v1
https://doi.org/10.1158/1535-7163.22507480.v1
Autor:
David A. Tice, Robert E. Hollingsworth, Ronald Herbst, Bahija Jallal, Philipp Steiner, Ping Tsui, Partha Chowdhury, Chunning Yang, Leslie Wetzel, Ray Rothstein, Hong Chen, Ravinder Tammali, Krista Kinneer, Kevin Schifferli, Rosa A. Carrasco, Zhan Xiao
Methods and figure legends for supplemental data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e19fb28b03753808f69ff05b3db5351
https://doi.org/10.1158/1535-7163.22507483
https://doi.org/10.1158/1535-7163.22507483
Autor:
Partha Chowdhury, Volkan Sarp, Ali Kilcik, Pratap Chandra Ray, Jean-Pierre Rozelot, Vladimir N Obridko
Publikováno v:
Monthly Notices of the Royal Astronomical Society. 513:4152-4158
The sunspot cycle waxes and wanes over a period of about 11 years and modulates ‘space weather’. Therefore, predicting the maximum amplitude of the solar cycle is an important goal for both solar physics and space weather. It is clear nowadays th
Autor:
Partha Chowdhury, Yang-Hsiang Chan
Publikováno v:
Molecular Systems Design & Engineering. 7:702-719
This mini-review outlines the recent designs of D–A–D based Pdots with NIR-II fluorescence. Several strategies for molecular engineering are summarized to overcome the emission energy gap law. Their applications of bio-imaging are also included.