Anakinra for palmoplantar pustulosis: results from a randomized, double-blind, multicentre, two-staged, adaptive placebo-controlled trial (APRICOT)

Autor: Cro, S., Cornelius, V.R., Pink, A.E., Wilson, R., Pushpa‐Rajah, A., Patel, P., Abdul‐Wahab, A., August, S., Azad, J., Becher, G., Chapman, A., Dunnil, G., Ferguson, A.D., Fogo, A., Ghaffar, S.A., Ingram, J.R., Kavakleiva, S., Ladoyanni, E., Leman, J.A., Macbeth, A.E., Makrygeoegou, A., Parslew, R., Ryan, A.J., Sharma, A., Shipman, A.R., Sinclair, C., Wachsmuth, R., Woolf, R.T., Wright, A., McAteer, H., Barker, J.N.W.N., Burden, A.D., Griffiths, C.E.M., Reynolds, N.J., Warren, R.B., Lachmann, H.J., Capon, F., Smith, C.H., APRICOT Study Group

Background:\ud Palmoplantar pustulosis (PPP) is a rare, debilitating, chronic inflammatory skin disease that affects the hands and feet. Clinical, immunological and genetic findings suggest a pathogenic role for interleukin (IL)-1.\ud \ud Objectives:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::d5e5c0cbe1ee379a68c282e9c437d5f3
https://eprints.gla.ac.uk/250468/1/250468.pdf

A framework for multi-omic prediction of treatment response to biologic therapy for psoriasis

Autor: Foulkes, AC, Watson, DS, Carr, DF, Kenny, JG, Slidel, T, Parslew, R, Pirmohamed, M, Consortium, PSORT, Anders, S, Reynolds, NJ, Griffiths, CEM, Warren, RB, Barnes, MR

Publikováno v: PSORT Consortium 2019, ' A Framework for Multi-Omic Prediction of Treatment Response to Biologic Therapy for Psoriasis ', The Journal of investigative dermatology, vol. 139, no. 1, pp. 100-107 . https://doi.org/10.1016/j.jid.2018.04.041
J Invest Dermatol
JOURNAL OF INVESTIGATIVE DERMATOLOGY

Biologic therapies have shown high efficacy in psoriasis, but individual response varies and is poorly understood. To inform biomarker discovery in the Psoriasis Stratification to Optimise Relevant Therapy (i.e., PSORT) study, we evaluated a comprehe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25d1f7f6b0c27c071487ce59f1e2e901
https://ora.ox.ac.uk/objects/uuid:93ee01fc-376c-4176-af28-f1de3ebf4bcf

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Warfarin treatment of chronic idiopathic urticaria and angio-oedema.

Autor: Parslew, R., Pryce, D., Ashworth, J., Friedmann, P.S.

Publikováno v: Clinical & Experimental Allergy. Aug2000, Vol. 30 Issue 8, p1161. 5p.