Výsledky vyhledávání - "Parsa Rasouli"

Potential Long-Term Consequences of Fad Diets on Health, Cancer, and Longevity: Lessons Learned from Model Organism Studies

Autor: Douglas M. Ruden, Xiangyi Lu, Parsa Rasouli

Publikováno v: Technology in Cancer Research & Treatment. 6:247-254

While much of the third world starves, many in the first world are undergoing an obesity epidemic, and the related epidemics of type II diabetes, heart disease, and other diseases associated with obesity. The amount of economic wealth being directly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af6e6022cad400ad852c16dcfbf6aaf4
https://doi.org/10.1177/153303460700600312

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Massively parallel resequencing of the isogenic Drosophila melanogaster strain w(1118); iso-2; iso-3 identifies hotspots for mutations in sensory perception genes

Autor: Parsa Rasouli, Adrian E. Platts, Douglas M. Ruden, Susan Land, Lang Chen, Grier P. Page, Xiangyi Lu, Luan Wang

Publikováno v: Fly. 3(3)

We used the Illumina reversible-short sequencing technology to obtain 17-fold average depth (s.d. approximately 8) of approximately 94% of the euchromatic genome and approximately 1-5% of the heterochromatin sequence of the Drosophila melanogaster is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::123de0ca8f47f222456f1d330717dabd
https://pubmed.ncbi.nlm.nih.gov/19690466

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Genetical toxicogenomics in Drosophila identifies master-modulatory loci that are regulated by developmental exposure to lead

Autor: Bernard Possidente, Mark D. Garfinkel, Grier P. Page, Helmut V. B. Hirsch, Lang Chen, Xiangyi Lu, Parsa Rasouli, Debra Possidente, Douglas M. Ruden, Luan Wang

Publikováno v: Neurotoxicology. 30(6)

The genetics of gene expression in recombinant inbred lines (RILs) can be mapped as expression quantitative trait loci (eQTLs). So-called "genetical genomics" studies have identified locally acting eQTLs (cis-eQTLs) for genes that show differences in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aa62eb136097f7b7c03163057a32c9b
https://pubmed.ncbi.nlm.nih.gov/19737576

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Epigenetics, Environment, and Evolution

Autor: Parsa Rasouli, Xiangyi Lu, Douglas M. Ruden

Publikováno v: Epigenetics in BIOLOGY and MEDICINE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7727c2252163364b3d0dc044cccd53ec
https://doi.org/10.1201/9781420007077-14

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The EDGE Hypothesis: Epigenetically Directed Genetic Errors in Repeat-Containing Proteins (RCPs) Involved in Evolution, Neuroendocrine Signaling, and Cancer

Autor: Mark D. Garfinkel, Douglas M. Ruden, Xiangyi Lu, D. Curtis Jamison, John N. Weinstein, Barry R. Zeeberg, Parsa Rasouli

Trans-generational epigenetic phenomena, such as contamination with endocrine-disrupting chemicals (EDCs) that decrease fertility and the global methylation status of DNA in the offspring, are of great concern because they may affect health, particul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b38daab607b95af975c7840011c2aef
https://europepmc.org/articles/PMC2716011/

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Possible effects of early treatments of hsp90 inhibitors on preventing the evolution of drug resistance to other anti-cancer drugs

Autor: Parsa Rasouli, Douglas M. Ruden, Li Xiao

Publikováno v: Current medicinal chemistry. 14(2)

Hsp90 is a chaperone that is critically important for both cancer progression and tumor survival. Hsp90 is an exciting target for anti-cancer drugs because most of the proteins that interact with Hsp90 are known to be in the cell cycle, signaling and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98c3c78786fcc2811e00dae0b2f10f22
https://pubmed.ncbi.nlm.nih.gov/17266581

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