Memantine, Simvastatin, and Epicatechin Inhibit 7-Ketocholesterol-induced Apoptosis in Retinal Pigment Epithelial Cells But Not Neurosensory Retinal Cells In Vitro

Autor: A. Neekhra, Baruch D. Kuppermann, Kevin Schneider, M. Cristina Kenney, Julia Tran, Khoa Pham, Ashish Sharma, Parsa R Esfahani, Marilyn Chwa, Ana L. Gramajo, S. Luthra, Saffar Mansoor

Publikováno v: Journal of Ophthalmic & Vision Research, Vol 15, Pp 470-480 (2020)
Journal of Ophthalmic & Vision Research
Journal of ophthalmic & vision research, vol 15, iss 4

Purpose: 7-ketocholesterol (7kCh), a natural byproduct of oxidation in lipoprotein deposits is implicated in the pathogenesis of diabetic retinopathy and age-related macular degeneration (AMD). This study was performed to investigate whether several

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e083349a984555f71f565155679879ba
https://doaj.org/article/295d056fd3cc4cc0855f0b3f4cee8e80