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Toxicologic Pathology Forum: Opinion on Obligatory Microscopic Examination of Intermediate-Dose Groups in Toxicity Studies With Biotherapeutics in Cynomolgus Monkeys.

Autor: Parrula C; Preclinical Safety Evaluation, 2184Vertex Pharmaceuticals Incorporated, Boston, MA, USA., Dincer Z; Pathology, 63899Covance Laboratories Limited, Harrogate, United Kingdom., Geoly FJ; 105623Worldwide Research & Development, Pfizer Inc, Groton, CT, USA., De Vera Mudry MC; 1529Roche Pharma Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center, Basel, Switzerland., Mysore J; Drug Safety Evaluation, 3971Bristol-Myers Squibb, New Brunswick, NJ, USA., Wuersch K; PreClinical Safety, 98560Novartis AG, Basel, Switzerland.

Publikováno v: Toxicologic pathology [Toxicol Pathol] 2020 Dec; Vol. 48 (8), pp. 939-943. Date of Electronic Publication: 2020 Nov 28.

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HTLV‐1 infected T cells cause bone loss via small extracellular vesicles.

Autor: Pokhrel, Nitin Kumar¹ (AUTHOR), Panfil, Amanda R.² (AUTHOR), Habib, Haniya¹ (AUTHOR), Seeniraj, Shamreethaa¹ (AUTHOR), Joseph, Ancy³ (AUTHOR), Rauch, Daniel³ (AUTHOR), Cox, Linda¹ (AUTHOR), Sprung, Robert⁴ (AUTHOR), Gilmore, Petra Erdmann⁴ (AUTHOR), Zhang, Qiang⁴ (AUTHOR), Townsend, Robert Reid⁴ (AUTHOR), Yu, Lianbo⁵ (AUTHOR), Yilmaz, Ayse Selen⁶ (AUTHOR), Aurora, Rajeev⁷ (AUTHOR), Park, William⁷ (AUTHOR), Ratner, Lee³ (AUTHOR), Weilbaecher, Katherine N.³ (AUTHOR), Veis, Deborah J.^1,8,9 (AUTHOR) dveis@wustl.edu

Publikováno v: Journal of Extracellular Vesicles. Oct2024, Vol. 13 Issue 10, p1-14. 14p.

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Akademický článek

Evaluation of microRNAs-208 and 133a/b as differential biomarkers of acute cardiac and skeletal muscle toxicity in rats.

Autor: Calvano J; Drug Safety Evaluation, Bristol-Myers Squibb, 1 Squibb Drive, New Brunswick, NJ 08903, United States. Electronic address: Jacqueline.Calvano@bms.com., Achanzar W; Drug Safety Evaluation, Bristol-Myers Squibb, 1 Squibb Drive, New Brunswick, NJ 08903, United States., Murphy B; Drug Safety Evaluation, Bristol-Myers Squibb, 1 Squibb Drive, New Brunswick, NJ 08903, United States., DiPiero J; Discovery Toxicology, Bristol-Myers Squibb, Route 206 and Province Line Road, Lawrenceville, NJ 08540, United States., Hixson C; Drug Safety Evaluation, Bristol-Myers Squibb, 1 Squibb Drive, New Brunswick, NJ 08903, United States., Parrula C; Drug Safety Evaluation, Bristol-Myers Squibb, 1 Squibb Drive, New Brunswick, NJ 08903, United States., Burr H; Drug Safety Evaluation, Bristol-Myers Squibb, 1 Squibb Drive, New Brunswick, NJ 08903, United States., Mangipudy R; Drug Safety Evaluation, Bristol-Myers Squibb, 1 Squibb Drive, New Brunswick, NJ 08903, United States., Tirmenstein M; Drug Safety Evaluation, Bristol-Myers Squibb, 1 Squibb Drive, New Brunswick, NJ 08903, United States.

Publikováno v: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2016 Dec 01; Vol. 312, pp. 53-60. Date of Electronic Publication: 2015 Nov 25.

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The role of alcohol extract of cranberry in improving serum indices of experimental metaproterenol‐induced heart damage in rats.

Autor: Salmasi, Kimia¹ (AUTHOR), Hassanpour, Ali² (AUTHOR) a_hasanpour@iaut.ac.ir, Amouoghli Tabrizi, Bahram² (AUTHOR), Moghaddam, Sina³ (AUTHOR)

Publikováno v: Food Science & Nutrition. Oct2023, Vol. 11 Issue 10, p6670-6675. 6p.

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Measles virotherapy in a mouse model of adult T-cell leukaemia/lymphoma.

Autor: Parrula C; Department of Veterinary Biosciences, The Ohio State University, Columbus, Ohio, USA., Fernandez SA; Comprehensive Cancer Center, The Arthur James Cancer Hospital and Research Institute, The Ohio State University, Columbus, Ohio, USA.; Center for Biostatistics, The Ohio State University, Columbus, Ohio, USA., Zimmerman B; Department of Veterinary Biosciences, The Ohio State University, Columbus, Ohio, USA., Lairmore M; Center for Retrovirus Research, The Ohio State University, Columbus, Ohio, USA.; Comprehensive Cancer Center, The Arthur James Cancer Hospital and Research Institute, The Ohio State University, Columbus, Ohio, USA.; Department of Veterinary Biosciences, The Ohio State University, Columbus, Ohio, USA., Niewiesk S; Center for Retrovirus Research, The Ohio State University, Columbus, Ohio, USA.; Comprehensive Cancer Center, The Arthur James Cancer Hospital and Research Institute, The Ohio State University, Columbus, Ohio, USA.; Department of Veterinary Biosciences, The Ohio State University, Columbus, Ohio, USA.

Publikováno v: The Journal of general virology [J Gen Virol] 2011 Jun; Vol. 92 (Pt 6), pp. 1458-1466. Date of Electronic Publication: 2011 Feb 16.

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Multicentric mast cell tumors in a horse.

Autor: Millward LM; Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH 43210, USA. millward.7@buckeyemail.osu.edu, Hamberg A, Mathews J, Machado-Parrula C, Premanandan C, Hurcombe SD, Radin MJ, Wellman ML

Publikováno v: Veterinary clinical pathology [Vet Clin Pathol] 2010 Sep; Vol. 39 (3), pp. 365-70.

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Akademický článek

Cervical thymoma originating in ectopic thymic tissue in a cat.

Autor: Lara-Garcia A; Department of Veterinary Clinical Sciences and Veterinary Teaching Hospital, College of Veterinary Medicine, The Ohio State University, Columbus, OH 43210, USA. lara-garcia.3@osu.edu, Wellman M, Burkhard MJ, Machado-Parrula C, Valli VE, Stromberg PC, Couto CG

Publikováno v: Veterinary clinical pathology [Vet Clin Pathol] 2008 Dec; Vol. 37 (4), pp. 397-402.

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