Generation and Study of Antibodies against Two Triangular Trimers Derived from Aβ.

Autor: Kreutzer AG; Department of Chemistry, University of California Irvine, Irvine, CA 92697., Malonis RJ; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461., Parrocha CMT; Department of Pharmaceutical Sciences, University of California Irvine, Irvine, CA 92697., Tong K; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461., Guaglianone G; Department of Chemistry, University of California Irvine, Irvine, CA 92697., Nguyen JT; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461., Diab MN; Department of Chemistry, University of California Irvine, Irvine, CA 92697., Lai JR; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461., Nowick JS; Department of Chemistry, University of California Irvine, Irvine, CA 92697.; Department of Pharmaceutical Sciences, University of California Irvine, Irvine, CA 92697.

Publikováno v: Peptide science (Hoboken, N.J.) [Pept Sci (Hoboken)] 2024 Mar; Vol. 116 (2). Date of Electronic Publication: 2023 Sep 18.

Probing differences among Aβ oligomers with two triangular trimers derived from Aβ.

Autor: Kreutzer AG; Department of Chemistry, University of California Irvine, Irvine, CA 92697., Guaglianone G; Department of Chemistry, University of California Irvine, Irvine, CA 92697., Yoo S; Department of Chemistry, University of California Irvine, Irvine, CA 92697., Parrocha CMT; Department of Pharmaceutical Sciences, University of California Irvine, Irvine, CA 92697., Ruttenberg SM; Department of Chemistry, University of California Irvine, Irvine, CA 92697., Malonis RJ; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461., Tong K; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461., Lin YF; Resource for Native Mass Spectrometry Guided Structural Biology, The Ohio State University, Columbus, OH 43210., Nguyen JT; Department of Pharmaceutical Sciences, University of California Irvine, Irvine, CA 92697., Howitz WJ; Department of Chemistry, University of California Irvine, Irvine, CA 92697., Diab MN; Department of Chemistry, University of California Irvine, Irvine, CA 92697., Hamza IL; Department of Chemistry, University of California Irvine, Irvine, CA 92697., Lai JR; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461., Wysocki VH; Resource for Native Mass Spectrometry Guided Structural Biology, The Ohio State University, Columbus, OH 43210., Nowick JS; Department of Chemistry, University of California Irvine, Irvine, CA 92697.; Department of Pharmaceutical Sciences, University of California Irvine, Irvine, CA 92697.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 May 30; Vol. 120 (22), pp. e2219216120. Date of Electronic Publication: 2023 May 22.

A cyclic peptide inhibitor of the SARS-CoV-2 main protease.

Autor: Kreutzer AG; Department of Chemistry, University of California, Irvine, CA, 92697-2025, United States., Krumberger M; Department of Chemistry, University of California, Irvine, CA, 92697-2025, United States., Diessner EM; Department of Chemistry, University of California, Irvine, CA, 92697-2025, United States; California Institute for Telecommunications and Information Technology, University of California, Irvine, CA, 92697-2025, United States., Parrocha CMT; Department of Pharmaceutical Sciences, University of California, Irvine, CA, 92697-2025, United States., Morris MA; Department of Chemistry, University of California, Irvine, CA, 92697-2025, United States., Guaglianone G; Department of Chemistry, University of California, Irvine, CA, 92697-2025, United States., Butts CT; California Institute for Telecommunications and Information Technology, University of California, Irvine, CA, 92697-2025, United States; Departments of Sociology, Statistics, Computer Science, and Electrical Engineering and Computer Science, University of California, Irvine, CA, 92697-2025, United States., Nowick JS; Department of Chemistry, University of California, Irvine, CA, 92697-2025, United States; Department of Pharmaceutical Sciences, University of California, Irvine, CA, 92697-2025, United States. Electronic address: jsnowick@uci.edu.

Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2021 Oct 05; Vol. 221, pp. 113530. Date of Electronic Publication: 2021 May 05.

Structure-Based Drug Design of an Inhibitor of the SARS-CoV-2 (COVID-19) Main Protease Using Free Software: A Tutorial for Students and Scientists.

Autor: Zhang S; Department of Chemistry, University of California, Irvine, Irvine, California 92697-2025, United States., Krumberger M; Department of Chemistry, University of California, Irvine, Irvine, California 92697-2025, United States., Morris MA; Department of Chemistry, University of California, Irvine, Irvine, California 92697-2025, United States., Parrocha CMT; Department of Pharmaceutical Sciences, University of California, Irvine, Irvine, California 92697-2025, United States., Griffin JH; Department of Chemistry, University of California, Irvine, Irvine, California 92697-2025, United States., Kreutzer AG; Department of Chemistry, University of California, Irvine, Irvine, California 92697-2025, United States., Nowick JS; Department of Chemistry, University of California, Irvine, Irvine, California 92697-2025, United States.; Department of Pharmaceutical Sciences, University of California, Irvine, Irvine, California 92697-2025, United States.

Publikováno v: ChemRxiv : the preprint server for chemistry [ChemRxiv] 2020 Aug 12. Date of Electronic Publication: 2020 Aug 12.