Decoupling of DNA methylation and activity of intergenic LINE-1 promoters in colorectal cancer

Autor: Vafadar-Isfahani, Natasha, Parr, Christina, McMillan, Lara E., Sanner, Juliane, Yeo, Zhao, Saddington, Stephen, Peacock, Oliver, Cruickshanks, Hazel A., Meehan, Richard R., Lund, Jonathan N., Tufarelli, Cristina

Publikováno v: Vafadar-Isfahani, N, Parr, C, McMillan, L E, Sanner, J, Yeo, Z, Saddington, S, Peacock, O, Cruickshanks, H A, Meehan, R R, Lund, J N & Tufarelli, C 2017, ' Decoupling of DNA methylation and activity of intergenic LINE-1 promoters in colorectal cancer ', Epigenetics . https://doi.org/10.1080/15592294.2017.1300729
Epigenetics

Hypomethylation of LINE-1 repeats in cancer has been proposed as the main mechanism behind their activation; this assumption, however, was based on findings from early studies that were biased towards young and transpositionally active elements. Here

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46e2eafa11e17184bf06427cf03fba83
https://www.pure.ed.ac.uk/ws/files/34462307/Decoupling_of_DNA_methylation_and_activity_of_intergenic_LINE_1_promoters_in_colorectal_cancer.pdf