Molecular mechanisms of thalidomide effectiveness on COVID-19 patients explained: ACE2 is a new ΔNp63α target gene.

Autor: Monteonofrio L; Dipartimento Di Ricerca E Tecnologie Avanzate, Istituto Nazionale Tumori Regina Elena IRCCS, 00144, Rome, Italy., Virdia I; Dipartimento Di Ricerca E Tecnologie Avanzate, Istituto Nazionale Tumori Regina Elena IRCCS, 00144, Rome, Italy., Pozzi S; Dipartimento Di Bioscienze, Università Degli Studi Di Milano, Via Celoria 26, 20133, Milan, Italy., Quadri R; Dipartimento Di Bioscienze, Università Degli Studi Di Milano, Via Celoria 26, 20133, Milan, Italy., Amendolare A; Istituto Di Biomembrane, Bioenergetica E Biotecnologie Molecolari (IBIOM), Consiglio Nazionale Delle Ricerche, 70025, Bari, Italy., Marzano F; Istituto Di Biomembrane, Bioenergetica E Biotecnologie Molecolari (IBIOM), Consiglio Nazionale Delle Ricerche, 70025, Bari, Italy., Braile M; Dipartimento Di Bioscienze, Università Degli Studi Di Milano, Via Celoria 26, 20133, Milan, Italy., Sulfaro V; Dipartimento Di Bioscienze, Università Degli Studi Di Milano, Via Celoria 26, 20133, Milan, Italy., Paroni M; Dipartimento Di Bioscienze, Università Degli Studi Di Milano, Via Celoria 26, 20133, Milan, Italy., Tullo A; Istituto Di Biomembrane, Bioenergetica E Biotecnologie Molecolari (IBIOM), Consiglio Nazionale Delle Ricerche, 70025, Bari, Italy., Soddu S; Dipartimento Di Ricerca E Tecnologie Avanzate, Istituto Nazionale Tumori Regina Elena IRCCS, 00144, Rome, Italy., Guerrini L; Dipartimento Di Bioscienze, Università Degli Studi Di Milano, Via Celoria 26, 20133, Milan, Italy. luisa.guerrini@unimi.it.

Publikováno v: Journal of molecular medicine (Berlin, Germany) [J Mol Med (Berl)] 2024 Nov; Vol. 102 (11), pp. 1371-1380. Date of Electronic Publication: 2024 Sep 18.

AIEC-dependent pathogenic Th17 cell transdifferentiation in Crohn's disease is suppressed by rfaP and ybaT deletion.

Autor: Leccese G; Department of Biosciences, Università degli Studi di Milano, Milan, Italy., Chiara M; Department of Biosciences, Università degli Studi di Milano, Milan, Italy., Dusetti I; Department of Biosciences, Università degli Studi di Milano, Milan, Italy., Noviello D; Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy., Billard E; M2iSH, UMR 1071 Inserm, INRAe USC 1382, CRNH, University of Clermont Auvergne, Clermont-Ferrand, France., Bibi A; Department of Biosciences, Università degli Studi di Milano, Milan, Italy., Conte G; Department of Biosciences, Università degli Studi di Milano, Milan, Italy., Consolandi C; Institute of Biomedical Technologies, National Research Council (ITB-CNR), Segrate, Milan, Italy., Vecchi M; Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy., Conte MP; Department of Public Health and Infectious Diseases, 'Sapienza' University of Rome, Rome, Italy., Barnich N; M2iSH, UMR 1071 Inserm, INRAe USC 1382, CRNH, University of Clermont Auvergne, Clermont-Ferrand, France., Caprioli F; Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy., Facciotti F; Department of Biotechnology and Bioscience, University of Milano-Bicocca, Milan, Italy., Paroni M; Department of Biosciences, Università degli Studi di Milano, Milan, Italy.

Publikováno v: Gut microbes [Gut Microbes] 2024 Jan-Dec; Vol. 16 (1), pp. 2380064. Date of Electronic Publication: 2024 Jul 29.

An Intestinal Th17 Subset is Associated with Inflammation in Crohn's Disease and Activated by Adherent-invasive Escherichia coli.

Autor: Paroni M; INGM-National Institute of Molecular Genetics 'Romeo ed Enrica Invernizzi', Milan, Italy.; Department of Biosciences, Università degli Studi di Milano, Milan, Italy., Leccese G; Department of Biosciences, Università degli Studi di Milano, Milan, Italy., Ranzani V; INGM-National Institute of Molecular Genetics 'Romeo ed Enrica Invernizzi', Milan, Italy., Moschetti G; INGM-National Institute of Molecular Genetics 'Romeo ed Enrica Invernizzi', Milan, Italy., Chiara M; Department of Biosciences, Università degli Studi di Milano, Milan, Italy., Perillo F; Department of Experimental Oncology, European Institute of Oncology, Milan, Italy., Ferri S; Department of Biotechnology and Bioscience, University of Milano-Bicocca, Milan, Italy., Clemente F; INGM-National Institute of Molecular Genetics 'Romeo ed Enrica Invernizzi', Milan, Italy., Noviello D; Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy., Conforti FS; Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Ferrero S; Pathology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Department of Biomedical, Surgical, and Dental Sciences, Università degli Studi di Milano, Milan, Italy., Karnani B; INGM-National Institute of Molecular Genetics 'Romeo ed Enrica Invernizzi', Milan, Italy., Bosotti R; INGM-National Institute of Molecular Genetics 'Romeo ed Enrica Invernizzi', Milan, Italy., Vasco C; INGM-National Institute of Molecular Genetics 'Romeo ed Enrica Invernizzi', Milan, Italy., Curti S; INGM-National Institute of Molecular Genetics 'Romeo ed Enrica Invernizzi', Milan, Italy., Crosti MC; INGM-National Institute of Molecular Genetics 'Romeo ed Enrica Invernizzi', Milan, Italy., Gruarin P; INGM-National Institute of Molecular Genetics 'Romeo ed Enrica Invernizzi', Milan, Italy., Rossetti G; INGM-National Institute of Molecular Genetics 'Romeo ed Enrica Invernizzi', Milan, Italy.; Molecular Oncology and Immunology, FIRC Institute of Molecular Oncology [IFOM], Milan, Italy., Conte MP; Department of Public Health and Infectious Diseases, 'Sapienza' University of Rome, Rome, Italy., Vecchi M; Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy., Pagani M; INGM-National Institute of Molecular Genetics 'Romeo ed Enrica Invernizzi', Milan, Italy.; Molecular Oncology and Immunology, FIRC Institute of Molecular Oncology [IFOM], Milan, Italy.; Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy., Landini P; Department of Biosciences, Università degli Studi di Milano, Milan, Italy., Facciotti F; INGM-National Institute of Molecular Genetics 'Romeo ed Enrica Invernizzi', Milan, Italy.; Department of Experimental Oncology, European Institute of Oncology, Milan, Italy.; Department of Biotechnology and Bioscience, University of Milano-Bicocca, Milan, Italy., Abrignani S; INGM-National Institute of Molecular Genetics 'Romeo ed Enrica Invernizzi', Milan, Italy.; DISCCO, Department of Clinical Science and Community Health, University of Milan, Milan, Italy., Caprioli F; Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy., Geginat J; INGM-National Institute of Molecular Genetics 'Romeo ed Enrica Invernizzi', Milan, Italy.; DISCCO, Department of Clinical Science and Community Health, University of Milan, Milan, Italy.

Publikováno v: Journal of Crohn's & colitis [J Crohns Colitis] 2023 Dec 30; Vol. 17 (12), pp. 1988-2001.

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