Layilin Anchors Regulatory T cells in Skin

Autor: Isaac M. Neuhaus, Adam Fries, Sean Clancy, Hobart W. Harris, Pooja Mehta, Joshua M. Moreau, Jingxian Zhang, Adil Daud, Margaret M. Lowe, Hsin-Wen Chang, Devi P. Boda, Parminder Mankoo, Ian C. Boothby, Michael Rosenblum, Bahar Zirak, Kelly M. Mahuron, J. Liu, Sofia V. Gearty, Matthew F. Krummel, Wilson Liao, Esther A. Kim, Tiffany C. Scharschmidt, Victoire Gouirand

Publikováno v: J Immunol
Journal of immunology (Baltimore, Md. : 1950), vol 207, iss 7

Regulatory T cells (Tregs) reside in nonlymphoid tissues where they carry out unique functions. The molecular mechanisms responsible for Treg accumulation and maintenance in these tissues are relatively unknown. Using an unbiased discovery approach,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04e0a7de97b4c559d4d34b5722204772
https://europepmc.org/articles/PMC8489406/

Integrated analyses of microRNAs demonstrate their widespread influence on gene expression in high-grade serous ovarian carcinoma.

Autor: Chad J Creighton, Anadulce Hernandez-Herrera, Anders Jacobsen, Douglas A Levine, Parminder Mankoo, Nikolaus Schultz, Ying Du, Yiqun Zhang, Erik Larsson, Robert Sheridan, Weimin Xiao, Paul T Spellman, Gad Getz, David A Wheeler, Charles M Perou, Richard A Gibbs, Chris Sander, D Neil Hayes, Preethi H Gunaratne, Cancer Genome Atlas Research Network

Publikováno v: PLoS ONE, Vol 7, Iss 3, p e34546 (2012)

The Cancer Genome Atlas (TCGA) Network recently comprehensively catalogued the molecular aberrations in 487 high-grade serous ovarian cancers, with much remaining to be elucidated regarding the microRNAs (miRNAs). Here, using TCGA ovarian data, we su

Externí odkaz: https://doaj.org/article/50dceea670724dfcb15c0e1ec548ae13

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

Autor: Tatiana Nikolskaya, Hirohiko Kamiyama, Yuri Nikolsky, Philipp Angenendt, Rachel Karchin, Kenneth W. Kinzler, Manuel Hidalgo, Douglas Smith, Giovanni Parmigiani, Christine A. Iacobuzio-Donahue, Seung-Mo Hong, Eric S. Calhoun, James R. Eshleman, Siân Jones, Mihoko Kamiyama, Baojin Fu, Nickolas Papadopoulos, Elizabeth M. Jaffee, Bert Vogelstein, D. Williams Parsons, Victor E. Velculescu, Kimberly Walter, Hannah Carter, Anirban Maitra, Steven D. Leach, Alison P. Klein, Ming Tseh Lin, Antonio Jimeno, James Hartigan, Michael Goggins, Scott E. Kern, Parminder Mankoo, Ralph H. Hruban, Jimmy Lin, Xiaosong Zhang, Rebecca J. Leary

Publikováno v: Science. 321:1801-1806

There are currently few therapeutic options for patients with pancreatic cancer, and new insights into the pathogenesis of this lethal disease are urgently needed. Toward this end, we performed a comprehensive genetic analysis of 24 pancreatic cancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8bf8517650db79897873abba98ec424
https://doi.org/10.1126/science.1164368

ModBase, a database of annotated comparative protein structure models and associated resources

Autor: Andrej Sali, Ben Webb, Marc A. Marti-Renom, Rachel Karchin, David T. Barkan, Hannah Carter, Libusha Kelly, Fred P. Davis, Parminder Mankoo, David Eramian, Narayanan Eswar, Ursula Pieper

Publikováno v: Nucleic Acids Research
Nucleic Acids Research, 2013, 42 (D1), pp.D336-D346. ⟨10.1093/nar/gkt1144⟩
Nucleic Acids Research, Oxford University Press, 2013, 42 (D1), pp.D336-D346. ⟨10.1093/nar/gkt1144⟩

International audience; ModBase (http://salilab.org/modbase) is a database of annotated comparative protein structure models. The models are calculated by ModPipe, an auto- mated modeling pipeline that relies primarily on Modeller for fold assignment

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40a2735948661a7cec74711881f165e9
https://hal-pasteur.archives-ouvertes.fr/pasteur-01414232

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

Autor: Alessandro Olivi, Sueli Mieko Oba Shinjo, Victor E. Velculescu, Siân Jones, Stephen T. Keir, Darell D. Bigner, Tatiana Nikolskaya, Luis A. Diaz, Xiaosong Zhang, Hanna Tekleab, Dana A. Busam, Robert L. Strausberg, Roger E. McLendon, Bert Vogelstein, D. Williams Parsons, Doug R. Smith, Philipp Angenendt, Rebecca J. Leary, B.K. Ahmed Rasheed, Hai Yan, Yuri Nikolsky, Parminder Mankoo, Nick Papadopoulos, Gregory J. Riggins, Rachel Karchin, Kenneth W. Kinzler, Gary L. Gallia, Jimmy Lin, Giovanni Parmigiani, I-Mei Siu, Hannah Carter, Suely Kazue Nagahashi Marie, James Hartigan

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Glioblastoma multiforme (GBM) is the most common and lethal type of brain cancer. To identify the genetic alterations in GBMs, we sequenced 20,661 protein coding genes, determined the presence of amplifications and deletions using high-density oligon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdc5d0f3162b33b9ce2f5f97f8071f1b