Výsledky vyhledávání - "Parminder J.S. Vig"

Corticosteroids for Severe Coronavirus Disease 2019: High Time for High Dose Clinical Trials?

Autor: A. Arturo Leis, Joseph L. Verheijde, Parminder J.S. Vig, Dobrivoje S. Stokic

Over 3 million deaths into the COVID-19 pandemic, low dose corticosteroids are still the chief therapeutic intervention to decrease mortality in critically ill COVID-19 patients. However, the persistently high mortality rate (approximately 30%) and t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::875e655aa053fe608598c35a428282aa
https://doi.org/10.31219/osf.io/qvejk

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Boat, an AXH domain protein, suppresses the cytotoxicity of mutant ataxin-1

Autor: Joshua P. Thaler, Akifumi Mizutani, Lei Wang, Harini Rajan, William A. Alaynick, Chih-Cheng Tsai, Parminder J.S. Vig

Ataxin-1 is a neurodegenerative disorder protein whose glutamine-repeat expanded form causes spinocerebellar ataxia type 1 (SCA1) in humans and exerts cytotoxicity in Drosophila and mouse. We report here that the cytotoxicity caused by ataxin-1 is mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9b9e63e6898da22af7a141f71d56ddf
https://europepmc.org/articles/PMC1224676/

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