Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Parmida Ranji"'
Autor:
Parmida Ranji, Emma Jonasson, Lisa Andersson, Stefan Filges, Manuel Luna Santamaría, Christoffer Vannas, Soheila Dolatabadi, Anna Gustafsson, Ola Myklebost, Joakim Håkansson, Henrik Fagman, Göran Landberg, Pierre Åman, Anders Ståhlberg
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Myxoid liposarcoma (MLS) displays a distinctive tumor microenvironment and is characterized by the FUS::DDIT3 fusion oncogene, however, the precise functional contributions of these two elements remain enigmatic in tumor developme
Externí odkaz:
https://doaj.org/article/efac96b56a16441ab22d151be2064aa6
Autor:
Gabrielle T. Parkinson, Simona Salerno, Parmida Ranji, Joakim Håkansson, Yalda Bogestål, Yvonne Wettergren, Anders Ståhlberg, Elinor Bexe Lindskog, Göran Landberg
Publikováno v:
Cancer Medicine, Vol 10, Iss 3, Pp 867-882 (2021)
Abstract Background Colorectal cancer is the second most common cause of cancer‐related death worldwide and standardized therapies often fail to treat the more aggressive and progressive types of colorectal cancer. Tumor cell heterogeneity and infl
Externí odkaz:
https://doaj.org/article/9fd1ca475e2948c08ae20fc453919313
Autor:
Christoffer Vannas, Lisa Andersson, Soheila Dolatabadi, Parmida Ranji, Malin Lindén, Emma Jonasson, Anders Ståhlberg, Henrik Fagman, Pierre Åman
Publikováno v:
Biomedicines, Vol 10, Iss 3, p 624 (2022)
The therapeutic options for patients with relapsed or metastatic myxoid liposarcoma (MLS) remain scarce and there is currently no targeted therapy available. Inhibition of the HSP90 family of chaperones has been suggested as a possible therapeutic op
Externí odkaz:
https://doaj.org/article/95925dd05c4c4d0aa3024bc338a99d8e
Autor:
Göran Landberg, Emma Jonasson, Anna Gustafsson, Paul Fitzpatrick, Pauline Isakson, Joakim Karlsson, Erik Larsson, Andreas Svanström, Svanheidur Rafnsdottir, Emma Persson, Daniel Andersson, Jennifer Rosendahl, Sarunas Petronis, Parmida Ranji, Pernilla Gregersson, Ylva Magnusson, Joakim Håkansson, Anders Ståhlberg
Publikováno v:
Data in Brief, Vol 31, Iss , Pp 105860- (2020)
Patient-derived scaffolds (PDSs) generated from primary breast cancer tumors can be used to model the tumor microenvironment in vitro. Patient-derived scaffolds are generated by repeated detergent washing, removing all cells. Here, we analyzed the pr
Externí odkaz:
https://doaj.org/article/a296415c8e3d41e384ef36b83bd5436b
Autor:
Emma Svensk, Ranjan Devkota, Marcus Ståhlman, Parmida Ranji, Manish Rauthan, Fredrik Magnusson, Sofia Hammarsten, Maja Johansson, Jan Borén, Marc Pilon
Publikováno v:
PLoS Genetics, Vol 12, Iss 6, p e1006112 (2016)
[This corrects the article DOI: 10.1371/journal.pgen.1005982.].
Externí odkaz:
https://doaj.org/article/8aae184e117c4338aa3b04907f77ca33
Autor:
Emma Svensk, Ranjan Devkota, Marcus Ståhlman, Parmida Ranji, Manish Rauthan, Fredrik Magnusson, Sofia Hammarsten, Maja Johansson, Jan Borén, Marc Pilon
Publikováno v:
PLoS Genetics, Vol 12, Iss 4, p e1005982 (2016)
In spite of the worldwide impact of diabetes on human health, the mechanisms behind glucose toxicity remain elusive. Here we show that C. elegans mutants lacking paqr-2, the worm homolog of the adiponectin receptors AdipoR1/2, or its newly identified
Externí odkaz:
https://doaj.org/article/fc6b3cb3eb264188b96bcdea9988f39f
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e100033 (2014)
HMG-CoA reductase is the rate-limiting enzyme in the mevalonate pathway and the target of cholesterol-lowering statins. We characterized the C. elegans hmgr-1(tm4368) mutant, which lacks HMG-CoA reductase, and show that its phenotypes recapitulate th
Externí odkaz:
https://doaj.org/article/7d59a3acdccf4e4fb36f763e3745c8bd
Autor:
Simona Salerno, Joakim Håkansson, Yalda Bogestål, Yvonne Wettergren, Anders Ståhlberg, Elinor Bexe Lindskog, Göran Landberg, Gabrielle T Parkinson, Parmida Ranji
Publikováno v:
Cancer Medicine, Vol 10, Iss 3, Pp 867-882 (2021)
Cancer Medicine
Cancer Medicine
Background Colorectal cancer is the second most common cause of cancer‐related death worldwide and standardized therapies often fail to treat the more aggressive and progressive types of colorectal cancer. Tumor cell heterogeneity and influence fro
Autor:
Erik Larsson, Andreas Svanström, Pernilla Gregersson, Emma Jonasson, Anders Ståhlberg, Joakim Håkansson, Parmida Ranji, Svanheidur Rafnsdottir, Göran Landberg, Jennifer Rosendahl, Sarunas Petronis, Joakim Karlsson, Ylva Magnusson, Emma Persson, Anna Gustafsson, Daniel Andersson, Paul A. Fitzpatrick, Pauline Isakson
Publikováno v:
Data in Brief, Vol 31, Iss, Pp 105860-(2020)
Data in Brief
Data in Brief
Patient-derived scaffolds (PDSs) generated from primary breast cancer tumors can be used to model the tumor microenvironment in vitro. Patient-derived scaffolds are generated by repeated detergent washing, removing all cells. Here, we analyzed the pr
Publikováno v:
G3: Genes|Genomes|Genetics
The mevalonate pathway is responsible for the synthesis of cholesterol, coenzyme Q, and prenyl groups essential for small GTPase modification and function, and for the production of dolichols important for protein glycosylation. Statins, i.e., choles