Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Parmesh Gajjar"'
Autor:
Yuqing Gong, Peijue Zhang, Miyoung Yoon, Hao Zhu, Ameya Kohojkar, Andrew C. Hooker, Murray P. Ducharme, Jogarao Gobburu, Géraldine Cellière, Parmesh Gajjar, Bing V. Li, Raja Velagapudi, Yu Chung Tsang, Anna Schwendeman, James Polli, Lanyan Fang, Robert Lionberger, Liang Zhao
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 5, Pp 624-630 (2023)
Abstract On November 30, 2021, the US Food and Drug administration (FDA) and the Center for Research on Complex Generics (CRCG) hosted a virtual public workshop titled “Establishing the Suitability of Model‐Integrated Evidence (MIE) to Demonstrat
Externí odkaz:
https://doaj.org/article/7ba25868225a4671a0706b3a2c4392e8
Autor:
Elen Roberts, Sadiyah Rahman, Shajee Ahmed, Harri Dickinson, Parmesh Gajjar, Talbir Austin, Shanoo Budhdeo, Marcel de Matas, Paul Stott
Publikováno v:
British Journal of Pharmacy, Vol 8, Iss 2 (2023)
Forming amorphous solid dispersions (ASDs) is one method for improving the solubility and subsequent absorption of poorly-water soluble drugs. An ASD is a matrix of a poorly water-soluble compound with a hydrophilic polymer carrier, which stabilises
Externí odkaz:
https://doaj.org/article/9b95610aeb6240f2b83350dda9ebf8bd
Autor:
Parmesh Gajjar, Jake Dickinson, Harri Dickinson, Linette Ruston, Hitesh B Mistry, Claire Patterson, Paul A Dickinson
Publikováno v:
British Journal of Pharmacy, Vol 7, Iss 2 (2022)
Demonstrating bioequivalence (BE) is important for the development of lower-cost generic products, and also for approving post-submission manufacturing changes. However, for many complex parenteral products, BE demonstration can be very challenging.
Externí odkaz:
https://doaj.org/article/c0cbd0c6968b4276bb1ea30e5eb83198
Autor:
Parmesh Gajjar, Chris G. Johnson, James Carr, Kevin Chrispeels, J. M. N. T. Gray, Philip J. Withers
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)
Abstract When opening a box of mixed nuts, a common experience is to find the largest nuts at the top. This well-known effect is the result of size-segregation where differently sized ‘particles’ sort themselves into distinct layers when shaken,
Externí odkaz:
https://doaj.org/article/0e662af927b04fbcb9d7fc9d6529b740
Autor:
Yuqing Gong, Peijue Zhang, Miyoung Yoon, Hao Zhu, Ameya Kohojkar, Andrew C. Hooker, Murray P. Ducharme, Jogarao Gobburu, Géraldine Cellière, Parmesh Gajjar, Bing V. Li, Raja Velagapudi, Yu Chung Tsang, Anna Schwendeman, James Polli, Lanyan Fang, Robert Lionberger, Liang Zhao
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology. 12:624-630
Autor:
Parmesh Gajjar, Jake Dickinson, Harri Dickinson, Linette Ruston, Hitesh B. Mistry, Claire Patterson, Paul A. Dickinson
Publikováno v:
Gajjar, P, Dickinson, J, Dickinson, H, Ruston, L, Mistry, H B, Patterson, C & Dickinson, P A 2022, ' Determining bioequivalence possibilities of long acting injectables through population PK modelling ', European Journal of Pharmaceutical Sciences, vol. 179, pp. 106296 . https://doi.org/10.1016/j.ejps.2022.106296
Long acting injectables (LAI) products are a popular intervention for treating a number of chronic conditions,with their long drug release reducing the administration frequency and thus improving patient adherence.The extended release, however, can p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::215bae9bda3603ee7c158672ee47c0ab
https://doi.org/10.1016/j.ejps.2022.106296
https://doi.org/10.1016/j.ejps.2022.106296
Autor:
Thai T.H. Nguyen, Parmesh Gajjar, Jun Sun, Robert B. Hammond, Darragh Murnane, Benjamin Tordoff, Erik Lauridsen, Philip J. Withers, Kevin J. Roberts
Publikováno v:
Journal of Crystal Growth. 603:126986
Autor:
Christopher Johnson, John Gray, Kevin Chrispeels, Philip J. Withers, Parmesh Gajjar, James Carr
Publikováno v:
Gajjar, P, Johnson, C, Carr, J, Chrispeels, K, Gray, J & Withers, P 2021, ' Size segregation of irregular granular materials captured by time-resolved 3D imaging ', Scientific Reports, vol. 11, no. 1, 8352 . https://doi.org/10.1038/s41598-021-87280-1
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)
When opening a box of mixed nuts, a common experience is to find the largest nuts at the top. This well-known effect is the result of size-segregation where differently sized ‘particles’ sort themselves into distinct layers when shaken, vibrated
Autor:
Malte Storm, Timothy L. Burnett, Parmesh Gajjar, Alistair Garner, John J. Lewandowski, N.J. Henry Holroyd, Benjamin C. Palmer, James Carr, Visweswara Chakravarthy Gudla, Philip J. Withers
Publikováno v:
Corrosion Reviews
Environmentally induced cracking (EIC) in a sensitized high-strength AA5083 H131 alloy has been investigated using time-lapse synchrotron X-ray computed tomography combined with post-mortem correlative characterization. Small corrosion features delib
Autor:
Kevin J. Roberts, Hrishikesh Bale, Timothy L. Burnett, Samuel A. McDonald, Darragh Murnane, Ioanna Danai Styliari, Erik Mejdal Lauridsen, Robert B. Hammond, Philip J. Withers, Benjamin Tordoff, Jun Sun, Thai Thu Hien Nguyen, Parmesh Gajjar
Publikováno v:
Gajjar, P, Nguyen, T T H, Sun, J, Styliari, I D, Bale, H, Mcdonald, S, Burnett, T, Tordoff, B, Lauridsen, E, Hammond, R B, Murnane, D, Withers, P & Roberts, K J 2021, ' Crystallographic Tomography and Molecular Modelling of Structured Organic Polycrystalline Powders ', CrystEngComm . https://doi.org/10.1039/D0CE01712D
A fundamental understanding of the behaviour of polycrystalline materials, including pharmaceuticals, is vital for control of their physicochemical and crystalline properties, which in turn has the potential to improve drug product development for ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c20445b89198408fb999c28949ceea3a
https://www.research.manchester.ac.uk/portal/en/publications/crystallographic-tomography-and-molecular-modelling-of-structured-organic-polycrystalline-powders(ccf906d3-bd08-427e-92ec-a9f6359b5d7a).html
https://www.research.manchester.ac.uk/portal/en/publications/crystallographic-tomography-and-molecular-modelling-of-structured-organic-polycrystalline-powders(ccf906d3-bd08-427e-92ec-a9f6359b5d7a).html