Zobrazeno 1 - 10
of 1 532
pro vyhledávání: '"Parkkola A."'
Autor:
Johanna Lilja, Jasmin Kaivola, James R. W. Conway, Joni Vuorio, Hanna Parkkola, Pekka Roivas, Michal Dibus, Megan R. Chastney, Taru Varila, Guillaume Jacquemet, Emilia Peuhu, Emily Wang, Ulla Pentikäinen, Itziar Martinez D. Posada, Hellyeh Hamidi, Arafath K. Najumudeen, Owen J. Sansom, Igor L. Barsukov, Daniel Abankwa, Ilpo Vattulainen, Marko Salmi, Johanna Ivaska
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The KRAS oncogene drives many common and highly fatal malignancies. These include pancreatic, lung, and colorectal cancer, where various activating KRAS mutations have made the development of KRAS inhibitors difficult. Here we identify the s
Externí odkaz:
https://doaj.org/article/aab4a06c715b4e4481e20d3e6037ab7e
Autor:
Mikko Koivumäki, Laura Ekblad, Juan Lantero-Rodriguez, Nicholas J. Ashton, Thomas K. Karikari, Semi Helin, Riitta Parkkola, Jyrki Lötjönen, Henrik Zetterberg, Kaj Blennow, Juha O. Rinne, Anniina Snellman
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-15 (2024)
Abstract Background Alzheimer’s disease (AD) is characterized by the accumulation of amyloid-β (Aβ) plaques, neurofibrillary tau tangles, and neurodegeneration in the brain parenchyma. Here, we aimed to (i) assess differences in blood and imaging
Externí odkaz:
https://doaj.org/article/ec950c17ae934bbbad1dedba707143df
Autor:
Claudia Tato-Fernández, Laura L. Ekblad, Elina Pietilä, Virva Saunavaara, Semi Helin, Riitta Parkkola, Henrik Zetterberg, Kaj Blennow, Juha O. Rinne, Anniina Snellman
Publikováno v:
Neurobiology of Disease, Vol 192, Iss , Pp 106439- (2024)
Except for aging, carrying the APOE ε4 allele (APOE4) is the most important risk factor for sporadic Alzheimer's disease. APOE4 carriers may have reduced capacity to recycle lipids, resulting in white matter microstructural abnormalities. In this st
Externí odkaz:
https://doaj.org/article/74de84ee23144774a5173a4f384899cd
Autor:
Tato-Fernández, Claudia, Ekblad, Laura L., Pietilä, Elina, Saunavaara, Virva, Helin, Semi, Parkkola, Riitta, Zetterberg, Henrik, Blennow, Kaj, Rinne, Juha O., Snellman, Anniina
Publikováno v:
In Neurobiology of Disease March 2024 192
Autor:
Martin S. Lietzén, Andrea Mari, Ronja Ojala, Jaakko Hentilä, Kalle Koskensalo, Riikka Lautamäki, Eliisa Löyttyniemi, Riitta Parkkola, Virva Saunavaara, Anna K. Kirjavainen, Johan Rajander, Tarja Malm, Leo Lahti, Juha O. Rinne, Kirsi H. Pietiläinen, Patricia Iozzo, Jarna C. Hannukainen
Publikováno v:
Biomolecules, Vol 14, Iss 9, p 1070 (2024)
Obesity and sedentarism are associated with increased liver and pancreatic fat content (LFC and PFC, respectively) as well as impaired organ metabolism. Exercise training is known to decrease organ ectopic fat but its effects on organ metabolism are
Externí odkaz:
https://doaj.org/article/04969fed64184f7bbf66f75addef9065
Autor:
Mikael Laaksonen, Jaakko Rinne, Melissa Rahi, Jussi P. Posti, Ruut Laitio, Juri Kivelev, Ilkka Saarenpää, Dan Laukka, Juhana Frösen, Antti Ronkainen, Stepani Bendel, Jaakko Långsjö, Marika Ala-Peijari, Jani Saunavaara, Riitta Parkkola, Mikko Nyman, Ilkka K. Martikainen, Alex M. Dickens, Juha Rinne, Mika Valtonen, Teijo I. Saari, Timo Koivisto, Paula Bendel, Timo Roine, Antti Saraste, Tero Vahlberg, Juha Tanttari, Timo Laitio
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-17 (2023)
Abstract Background Aneurysmal subarachnoid hemorrhage (aSAH) is a neurological emergency, affecting a younger population than individuals experiencing an ischemic stroke; aSAH is associated with a high risk of mortality and permanent disability. The
Externí odkaz:
https://doaj.org/article/9d946299390741bfa6d617d14bb790b5
Autor:
Riitta Parkkola, Antti Saraste, Jaakko Rinne, Dan Laukka, Jooa Paturi, Melissa Rahi, Juri Kivelev, Maria Gardberg, Johanna Kuhmonen
Publikováno v:
BMJ Open, Vol 14, Iss 2 (2024)
Introduction Positron emission tomography (PET) imaging can be used to evaluate arterial wall inflammation in extracranial vascular diseases. However, the application of PET imaging in unruptured intracranial aneurysms (UIA) remains unexplored. Our o
Externí odkaz:
https://doaj.org/article/0fedfd6e736f491b87962d717ccb0d6e
Autor:
Backman, Emmilotta A., Luntamo, Laura, Parkkola, Riitta, Koikkalainen, Juha, Gardberg, Maria, Kaasinen, Valtteri
Publikováno v:
In Journal of the Neurological Sciences 15 December 2023 455
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