β-Catenin–mediated immune evasion pathway frequently operates in primary cutaneous melanomas

Autor: Nsengimana, Jérémie, Laye, Jon, Filia, Anastasia, O’Shea, Sally, Muralidhar, Sathya, Poźniak, Joanna, Droop, Alastair, Chan, May, Walker, Christy, Parkinson, Louise, Gascoyne, Joanne, Mell, Tracey, Polso, Minttu, Jewell, Rosalyn, Randerson-Moor, Juliette, Cook, Graham P., Bishop, D. Timothy, Newton-Bishop, Julia

Publikováno v: The Journal of Clinical Investigation

Immunotherapy prolongs survival in only a subset of melanoma patients, highlighting the need to better understand the driver tumor microenvironment. We conducted bioinformatic analyses of 703 transcriptomes to probe the immune landscape of primary cu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a831d062399dabd3e897ec41507d7609
http://europepmc.org/articles/PMC5919828

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Primary tumour PSMA intensity is an independent prognostic biomarker for biochemical recurrence-free survival following radical prostatectomy.

Autor: Roberts, Matthew J.^1,2,3 (AUTHOR) m.roberts2@uq.edu.au, Morton, Andrew⁴ (AUTHOR), Papa, Nathan⁵ (AUTHOR), Franklin, Anthony⁴ (AUTHOR), Raveenthiran, Sheliyan³ (AUTHOR), Yaxley, William J.⁴ (AUTHOR), Coughlin, Geoffrey^4,6 (AUTHOR), Gianduzzo, Troy^4,6 (AUTHOR), Kua, Boon^4,6 (AUTHOR), McEwan, Louise⁷ (AUTHOR), Wong, David⁷ (AUTHOR), Delahunt, Brett⁸ (AUTHOR), Egevad, Lars⁹ (AUTHOR), Samaratunga, Hemamali^4,10 (AUTHOR), Brown, Nicholas^4,7 (AUTHOR), Parkinson, Robert⁷ (AUTHOR), Emmett, Louise^11,12 (AUTHOR), Yaxley, John W.^1,4,6 (AUTHOR)

Publikováno v: European Journal of Nuclear Medicine & Molecular Imaging. 2022, Vol. 49 Issue 9, p3289-3294. 6p. 3 Charts, 1 Graph.

Total ankle replacement versus ankle arthrodesis for patients aged 50--85 years with end-stage ankle osteoarthritis: the TARVA RCT.

Autor: Goldberg, Andrew J., Chowdhury, Kashfia, Bordea, Ekaterina, Blackstone, James, Brooking, Deirdre, Deane, Elizabeth L., Hauptmannova, Iva, Cooke, Paul, Cumbers, Marion, Skene, Simon S., Doré, Caroline J.

Publikováno v: Health Technology Assessment; Mar2023, Vol. 27 Issue 5, pi-80, 92p

The Acoustic Self in English Modernism and Beyond : Writing Musically

Autor: Zoltan Varga

Drawing on the analogy between musical meaning-making and human subjectivity, this book develops the concept of the acoustic self, exploring the ways in which musical characterization and structure are related to issues of subject-representation in t