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Akademický článek

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Essential role of NAADP-evoked calcium release in glucose-mediated depolarization, [Ca2+]i spiking and insulin secretion in mouse pancreatic beta cell

Autor: Arredouani, A, Parkesh, R, Pillinger, T, Coltart, G, Clough, F, Shimomura, K, Aschcroft, F, Churchill, G, Galione, A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0692e153561733f51462e80481e0da05
https://ora.ox.ac.uk/objects/uuid:081a8d9d-4804-4f27-ad16-6967c80fb154

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Mechanistic Insight into the Enzymatic Reduction of Truncated Hemoglobin N of Mycobacterium tuberculosis: role of the CD loop and pre-A Motif in electron cycling

Autor: Singh, Sandeep, Thakur, Naveen, Oliveira, Ana, Petruk, Ariel Alcides, Hade, Mangesh Dattu, Sethi, Deepti, Bidon Chanal, Axel, Marti, Marcelo Adrian, Datta, H., Parkesh, R., Estrin, Dario Ariel, Luque, F. Javier, Dikshit, Kanak L.

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Background: The HbN of Mycobacterium tuberculosis carries a potent nitric-oxide dioxygenase activity despite lacking a reductase domain. Results: The NADH-ferredoxin reductase system acts as an efficient partner for the reduction of HbN. Conclusion:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::da03165f0799b9b47450cd255c707c08
http://www.jbc.org/content/289/31/21573

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Acidic NAADP-sensitive calcium stores in the endothelium: agonist-specific recruitment and role in regulating blood pressure

Autor: Brailoiu, G, Gurzu, B, Gao, X, Parkesh, R, Aley, P, Trifa, D, Galione, A, Dun, N, Madesh, M, Patel, S, Churchill, G, Brailoiu, E

Publikováno v: The Journal of biological chemistry. 285(48)

Accumulating evidence implicates nicotinic acid adenine dinucleotide phosphate (NAADP) in the control of Ca(2+)-dependent functions. Little, however, is known concerning its role in the vascular endothelium, a major regulator of blood pressure. Here,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2e0469afe56e14994e3b68a569f56e77
http://ora.ox.ac.uk/objects/uuid:6f5eb31c-b882-4f66-8c51-c954c72cacd7