ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity.

Autor: Liu G; Florida Research and Innovation Center, Cleveland Clinic, Port St Lucie, FL, USA.; Department of Microbiology, University of Chicago, Chicago, IL, USA., Lee JH; Florida Research and Innovation Center, Cleveland Clinic, Port St Lucie, FL, USA.; Department of Microbiology, University of Chicago, Chicago, IL, USA., Parker ZM; Department of Microbiology, University of Chicago, Chicago, IL, USA., Acharya D; Florida Research and Innovation Center, Cleveland Clinic, Port St Lucie, FL, USA.; Department of Microbiology, University of Chicago, Chicago, IL, USA., Chiang JJ; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA, USA., van Gent M; Florida Research and Innovation Center, Cleveland Clinic, Port St Lucie, FL, USA.; Department of Microbiology, University of Chicago, Chicago, IL, USA., Riedl W; Florida Research and Innovation Center, Cleveland Clinic, Port St Lucie, FL, USA.; Department of Microbiology, University of Chicago, Chicago, IL, USA., Davis-Gardner ME; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA, USA., Wies E; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA, USA., Chiang C; Florida Research and Innovation Center, Cleveland Clinic, Port St Lucie, FL, USA.; Department of Microbiology, University of Chicago, Chicago, IL, USA., Gack MU; Florida Research and Innovation Center, Cleveland Clinic, Port St Lucie, FL, USA. gackm@ccf.org.; Department of Microbiology, University of Chicago, Chicago, IL, USA. gackm@ccf.org.

Publikováno v: Nature microbiology [Nat Microbiol] 2021 Apr; Vol. 6 (4), pp. 467-478. Date of Electronic Publication: 2021 Mar 16.

TRIM23 mediates virus-induced autophagy via activation of TBK1.

Autor: Sparrer KMJ; Department of Microbiology, The University of Chicago, Chicago, IL, 60637, USA., Gableske S; Department of Microbiology, The University of Chicago, Chicago, IL, 60637, USA., Zurenski MA; Department of Microbiology, The University of Chicago, Chicago, IL, 60637, USA., Parker ZM; Department of Microbiology, The University of Chicago, Chicago, IL, 60637, USA., Full F; Department of Microbiology, The University of Chicago, Chicago, IL, 60637, USA., Baumgart GJ; Department of Microbiology, The University of Chicago, Chicago, IL, 60637, USA., Kato J; Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Pacheco-Rodriguez G; Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Liang C; Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA., Pornillos O; Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA, 22908, USA., Moss J; Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Vaughan M; Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Gack MU; Department of Microbiology, The University of Chicago, Chicago, IL, 60637, USA. mgack@uchicago.edu.

Publikováno v: Nature microbiology [Nat Microbiol] 2017 Nov; Vol. 2 (11), pp. 1543-1557. Date of Electronic Publication: 2017 Sep 04.

Role of the DNA Sensor STING in Protection from Lethal Infection following Corneal and Intracerebral Challenge with Herpes Simplex Virus 1.

Autor: Parker ZM; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, USA., Murphy AA; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, USA., Leib DA; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, USA david.a.leib@dartmouth.edu.

Publikováno v: Journal of virology [J Virol] 2015 Nov; Vol. 89 (21), pp. 11080-91. Date of Electronic Publication: 2015 Aug 26.

The differential interferon responses of two strains of Stat1-deficient mice do not alter susceptibility to HSV-1 and VSV in vivo.

Autor: Katzenell S; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756, United States., Chen Y; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756, United States., Parker ZM; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756, United States., Leib DA; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756, United States. Electronic address: david.a.leib@dartmouth.edu.

Publikováno v: Virology [Virology] 2014 Feb; Vol. 450-451, pp. 350-4. Date of Electronic Publication: 2014 Jan 14.

Elevated levels of the norspermidine synthesis enzyme NspC enhance Vibrio cholerae biofilm formation without affecting intracellular norspermidine concentrations.

Autor: Parker ZM; Department of Biology, Appalachian State University, Boone, NC 27599, USA., Pendergraft SS, Sobieraj J, McGinnis MM, Karatan E

Publikováno v: FEMS microbiology letters [FEMS Microbiol Lett] 2012 Apr; Vol. 329 (1), pp. 18-27. Date of Electronic Publication: 2012 Jan 30.