Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Parker Siddall"'
Autor:
Simona Zarini, Joseph T. Brozinick, Karin A. Zemski Berry, Amanda Garfield, Leigh Perreault, Anna Kerege, Hai Hoang Bui, Phil Sanders, Parker Siddall, Ming Shang Kuo, Bryan C. Bergman
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 10, Pp 100270- (2022)
Serum ceramides, especially C16:0 and C18:0 species, are linked to CVD risk and insulin resistance, but details of this association are not well understood. We performed this study to quantify a broad range of serum sphingolipids in individuals spann
Externí odkaz:
https://doaj.org/article/7d7ffd7ab7914895aaddc87b15411a05
Autor:
Rachel J. Roth Flach, Eliza Bollinger, Allan R. Reyes, Brigitte Laforest, Bethany L. Kormos, Shenping Liu, Matthew R. Reese, Luis A. Martinez Alsina, Leanne Buzon, Yuan Zhang, Bruce Bechle, Amy Rosado, Parag V. Sahasrabudhe, John Knafels, Samit K. Bhattacharya, Kiyoyuki Omoto, John C. Stansfield, Liam D. Hurley, LouJin Song, Lina Luo, Susanne B. Breitkopf, Mara Monetti, Teresa Cunio, Brendan Tierney, Frank J. Geoly, Jake Delmore, C. Parker Siddall, Liang Xue, Ka N. Yip, Amit S. Kalgutkar, Russell A. Miller, Bei B. Zhang, Kevin J. Filipski
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Branched chain amino acid (BCAA) catabolic impairments have been implicated in several diseases. Branched chain ketoacid dehydrogenase (BCKDH) controls the rate limiting step in BCAA degradation, the activity of which is inhibited by BCKDH k
Externí odkaz:
https://doaj.org/article/f9d9823491ce46a3808353f3a122b4ab
Autor:
Eliza Bollinger, Matthew Peloquin, Jenna Libera, Bina Albuquerque, Evanthia Pashos, Arun Shipstone, Angela Hadjipanayis, Zhongyuan Sun, Gang Xing, Michelle Clasquin, John C. Stansfield, Brendan Tierney, Steven Gernhardt, C. Parker Siddall, Timothy Greizer, Frank J. Geoly, Sarah R. Vargas, Lily C. Gao, George Williams, Mackenzie Marshall, Amy Rosado, Claire Steppan, Kevin J. Filipski, Bei B. Zhang, Russell A. Miller, Rachel J. Roth Flach
Publikováno v:
Molecular metabolism. 66
Branched chain amino acid (BCAA) catabolic defects are implicated to be causal determinates of multiple diseases. This work aimed to better understand how enhancing BCAA catabolism affected metabolic homeostasis as well as the mechanisms underlying t
Autor:
Zhongyuan Sun, Michelle Clasquin, Jake Delmore, Mary Piotrowski, Gang Xing, Teresa Cunio, Darren Dumlao, Angela Hadjipanayis, Rachel J. Roth Flach, Bei B. Zhang, Russell A. Miller, Evanthia Pashos, Matthew Peloquin, Bina Albuquerque, Eliza Bollinger, Chang Zou, Parker Siddall
Publikováno v:
Circulation Research. 125
Circulating increases in branched chain amino acid (BCAA) levels have long been associated with type II diabetes and metabolic syndrome. Emerging data also suggest that impaired BCAA catabolism may play a role in heart failure progression. BCAA are c
Autor:
Michelle Clasquin, Rachel J. Roth Flach, Zhongyuan Sun, Timothy Greizer, Gang Xing, Angela Hadjipanayis, Ghazal Hariri, Jenna L. Libera, Eliza Bollinger, Bei B. Zhang, Charles Parker Siddall, Arun Shipstone, Evanthia Pashos, Russell A. Miller
Publikováno v:
Diabetes. 68
Circulating increases in branched chain amino acid (BCAA) levels have long been associated with type 2 diabetes and metabolic syndrome. Emerging data also suggest that BCAA catabolism may play a role in heart failure progression. It is hypothesized t
Autor:
Phil Sanders, Samantha Bacon, Anna Kerege, Ming Shang Kuo, Leigh Perreault, Bryan C. Bergman, Allison Strauss, Hai Hoang Bui, Parker Siddall, Joseph T. Brozinick
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 309:E398-E408
Ceramides and sphingolipids are a family of lipid molecules that circulate in serum and accumulate in skeletal muscle, promoting insulin resistance. Plasma ceramide and dihydroceramide are related to insulin resistance, yet less is known regarding ot
Autor:
Melissa K. Thomas, Hai Hoang Bui, Anna Kerege, Phil Sanders, Travis Nemkov, Ming Shang Kuo, Kirk C. Hansen, Sean A. Newsom, Bryan C. Bergman, Angelo D'Alessandro, Joseph T. Brozinick, Samantha Bacon, Allison Strauss, Leigh Perreault, Katja Kiseljak-Vassiliades, Parker Siddall, Tao Wei
Several recent reports indicate that the balance of skeletal muscle phosphatidylcholine (PC) and phosphatidylethanolamine (PE) is a key determinant of muscle contractile function and metabolism. The purpose of this study was to determine relationship
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98e77e412a6edd9848ab2d2858c4af3a
https://europepmc.org/articles/PMC4891931/
https://europepmc.org/articles/PMC4891931/
Autor:
Anna Kerege, Allison Strauss, Hai Hoang Bui, Parker Siddall, Melissa K. Thomas, Leigh Perreault, Ming Shang Kuo, Samantha Bacon, Tao Wei, Phil Sanders, Joseph T. Brozinick, Bryan C. Bergman
Publikováno v:
Diabetologia. 59(4)
Ceramides and other sphingolipids comprise a family of lipid molecules that accumulate in skeletal muscle and promote insulin resistance. Chronic endurance exercise training decreases muscle ceramides and other sphingolipids, but less is known about
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 301:E825-E835
Adipose tissue controls energy homeostasis and systemic insulin sensitivity through the elaboration of a series of cytokines and hormones, collectively termed “adipokines.” We and others have identified Lcn2 as a novel adipokine, but its exact ro
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