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Autor:
Reece F Crumpler, Fan Fan, Jane J Ryu, Xing Fang, Shaoxun Wang, Luke B Strong, Parker S Elliot, Richard J. Roman, Baoying Zheng, Kirby N Thomas, Huawei Zhang
Publikováno v:
Hypertension. 78
20-HETE is synthesized from arachidonic acid by cytochrome P450 (CYP) enzymes 4A and 4F. Inactivating mutations in the CYP enzymes that produce 20-HETE are associated with hypertension and stroke in man. We previously revealed that inactivating varia