Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Parker Reitler"'
Autor:
Jessica Regan, Christian DeJarnette, Arturo Luna-Tapia, Josie E. Parker, Parker Reitler, Stacey Barnett, Katie M. Tucker, Steven L. Kelly, Glen E. Palmer
Publikováno v:
mBio, Vol 13, Iss 2 (2022)
ABSTRACT The azole antifungals inhibit sterol 14α-demethylase (S14DM), which depletes cellular ergosterol and promotes synthesis of the dysfunctional lipid 14α-methylergosta-8,24(28)-dien-3β,6α-diol, ultimately arresting growth. Mutations that in
Externí odkaz:
https://doaj.org/article/ef3d15f8a1ad4a89b45ba215dd9b1f99
Autor:
Arturo Luna-Tapia, Christian DeJarnette, Emily Sansevere, Parker Reitler, Arielle Butts, Kirk E. Hevener, Glen E. Palmer
Publikováno v:
mSphere, Vol 4, Iss 1 (2019)
ABSTRACT Calcium is a critically important secondary messenger of intracellular signal transduction in eukaryotes but must be maintained at low levels in the cytoplasm of resting cells to avoid toxicity. This is achieved by several pumps that activel
Externí odkaz:
https://doaj.org/article/6096f121cb3f41459643d166be2241b7
Autor:
Christian DeJarnette, Andrew T. Nishimoto, Leanna R Estredge, Glen E. Palmer, Arielle Butts, Tracy L. Peters, P. David Rogers, Michael P. Veve, Parker Reitler
Publikováno v:
Antimicrobial Agents and Chemotherapy. 63
The increasing incidence of and high mortality rates associated with invasive fungal infections (IFIs) impose an enormous clinical, social, and economic burden on humankind. In addition to microbiological resistance to existing antifungal drugs, the
Autor:
Arturo, Luna-Tapia, Christian, DeJarnette, Emily, Sansevere, Parker, Reitler, Arielle, Butts, Kirk E, Hevener, Glen E, Palmer
Publikováno v:
mSphere
Maintenance of Ca2+ homeostasis is important for fungal cells to respond to a multitude of stresses, as well as antifungal treatment, and for virulence in animal models. Here, we demonstrate that a P-type ATPase, Pmc1p, is required for Candida albica
Autor:
Arturo Luna-Tapia, Arielle Butts, Glen E. Palmer, Parker Reitler, Kirk E. Hevener, Christian DeJarnette, Emily Sansevere
Publikováno v:
mSphere, Vol 4, Iss 1 (2019)
mSphere, Vol 4, Iss 1, p e00715-18 (2019)
mSphere, Vol 4, Iss 1, p e00715-18 (2019)
Calcium is a critically important secondary messenger of intracellular signal transduction in eukaryotes but must be maintained at low levels in the cytoplasm of resting cells to avoid toxicity. This is achieved by several pumps that actively transpo
A Systematic Screen Reveals a Diverse Collection of Medications That Induce Antifungal Resistance in
Autor:
Arielle, Butts, Parker, Reitler, Andrew T, Nishimoto, Christian, DeJarnette, Leanna R, Estredge, Tracy L, Peters, Michael P, Veve, P David, Rogers, Glen E, Palmer
Publikováno v:
Antimicrobial agents and chemotherapy. 63(5)
The increasing incidence of and high mortality rates associated with invasive fungal infections (IFIs) impose an enormous clinical, social, and economic burden on humankind. In addition to microbiological resistance to existing antifungal drugs, the
The incidence of invasive fungal infections has risen significantly in recent decades as medical interventions have become increasingly aggressive. These infections are extremely difficult to treat due to the extremely limited repertoire of systemic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62fbd974afe03d75622290801f1fbc94
https://europepmc.org/articles/PMC6021626/
https://europepmc.org/articles/PMC6021626/