Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Parker J. Denz"'
Autor:
Samuel Speaks, Matthew I. McFadden, Ashley Zani, Abigail Solstad, Steve Leumi, Jack E. Roettger, Adam D. Kenney, Hannah Bone, Lizhi Zhang, Parker J. Denz, Adrian C. Eddy, Amal O. Amer, Richard T. Robinson, Chuanxi Cai, Jianjie Ma, Emily A. Hemann, Adriana Forero, Jacob S. Yount
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Influenza virus activates cellular inflammasome pathways, which can be both beneficial and detrimental to infection outcomes. Here, we investigate the function of the inflammasome-activated, pore-forming protein gasdermin D (GSDMD) during in
Externí odkaz:
https://doaj.org/article/1bdb4d643c5340eaab89b6eb41184ba9
Autor:
Jianjie Ma, Hua Zhu, Naresh Kumar, Lisa E. Dorn, Federica Accornero, Adam D. Kenney, Jeffrey Kawahara, Adrian Eddy, Ashley Zani, Jacob S. Yount, Parker J. Denz, Murugesan V. S. Rajaram, Stephanie L. Aron, Peng Chen, Samuel Speaks, Clara Gilbert, Ryan A. Langlois, Chuanxi Cai, Lizhi Zhang, Nahara Vargas-Maldonado
Cardiac dysfunction is a common extrapulmonary complication of severe influenza virus infection. Prevailing models propose that influenza-associated heart dysfunction is indirectly triggered by cytokine mediated cardiotoxicity downstream of the infla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba7a56afbc5db6e47c42290f82105ddd
https://doi.org/10.1101/2021.10.27.466128
https://doi.org/10.1101/2021.10.27.466128
Autor:
Emily Hemann, Mark E. Peeples, Eman Abdelrazik, Estelle Cormet-Boyaka, Asmaa Badr, Prosper N. Boyaka, Maciej Pietrzak, Shady Estfanous, Jeffrey Kawahara, Ashley Zani, Krishnan Mahesh, Adam D. Kenney, Jianrong Li, Oscar Rosas Mejia, Mostafa Eltobgy, Owen Whitham, Shahid M Nimjee, Richard T. Robinson, Andrea Tedeschi, Santiago Partida-Sanchez, Parker J. Denz, Frank Roberto, Adrian Eddy, Jacob S. Yount, Amy Webb, Cierra Carafice, Rachael E. Rayner, Eunsoo Kim, Mikhail A. Gavrilin, Kylene Daily, Jian Zhu, Amal O. Amer, Jianwen Que, Luanne Hall-Stoodley, Adriana Forero, Mijia Lu, Stephanie Seveau
SARS-CoV-2 is a worldwide health concern, and new treatment strategies are needed 1. Targeting inflammatory innate immunity pathways holds therapeutic promise, but effective molecular targets remain elusive. Here, we show that human caspase-4 (CASP4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af96809a1af3397cecceec5bce8d10b8
https://doi.org/10.1101/2021.09.24.461743
https://doi.org/10.1101/2021.09.24.461743