Final results of the phase 1/2, open-label clinical study of intravenous recombinant human N-acetyl-a-d-glucosaminidase (SBC-103) in children with mucopolysaccharidosis IIIB

Autor: Whitley CB, Vijay S, Yao B, Pineda M, Parker GJM, Rojas-Caro S, Zhang X, Dai Y, Cinar A, Bubb G, Patki KC, Escolar ML

Publikováno v: MOLECULAR GENETICS AND METABOLISM
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
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r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu

Mucopolysaccharidosis IIIB is caused by a marked decrease in N-acetyl-a-d-glucosaminidase (NAGLU) enzyme activity, which leads to the accumulation of heparan sulfate in key organs, progressive brain atrophy, and neurocognitive decline. In this open-l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7bcf7cf116353a82256c4556134b914c
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=15561

Oxygen Enhanced Optoacoustic Tomography (OE-OT) Reveals Vascular Dynamics in Murine Models of Prostate Cancer

Autor: Tomaszewski, MR, Gonzalez, IQ, O'Connor, JPB, Abeyakoon, O, Parker, GJM, Williams, KJ, Gilbert, FJ, Bohndiek, SE

Poor oxygenation of solid tumours has been linked with resistance to chemo- and radio-therapy and poor patient outcomes, hence non-invasive imaging of oxygen supply and demand in tumours could improve disease staging and therapeutic monitoring. Optoa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86a6de5607ede412488040eef5827b79
https://www.repository.cam.ac.uk/handle/1810/266784

Beurteilung mikrovaskulärer Charakteristika von hochgradigen Gliomen mit Kontrastmittel-gestützter dynamischer MRT

Autor: Harrer, JU, Haroon, HA, Buckley, DL, Embleton, K, Roberts, C, Jackson, A, Parker, GJM

Publikováno v: Aktuelle Neurologie; 20240101, Issue: Preprints

Combining tractography and coherence measures to identify connectivity within a neural network for reading

Autor: Welbourne SR, Embleton K, Haroon HA, Parker GJM, Lambon Ralph MA.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2295::605061d3914f82564c9070fdc5abbfbb
http://www.manchester.ac.uk/escholar/uk-ac-man-scw:2d2542

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