hiPSC-derived cardiomyocytes as a model to study the role of small-conductance Ca2+-activated K+ (SK) ion channel variants associated with atrial fibrillation

Autor: Hosna Babini, Verónica Jiménez-Sábado, Ekaterina Stogova, Alia Arslanova, Mariam Butt, Saif Dababneh, Parisa Asghari, Edwin D. W. Moore, Thomas W. Claydon, Nipavan Chiamvimonvat, Leif Hove-Madsen, Glen F. Tibbits

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 12 (2024)

Atrial fibrillation (AF), the most common arrhythmia, has been associated with different electrophysiological, molecular, and structural alterations in atrial cardiomyocytes. Therefore, more studies are required to elucidate the genetic and molecular

Externí odkaz: https://doaj.org/article/9fb5fce9358747888e15f06698dd86da

Cardiac ryanodine receptor distribution is dynamic and changed by auxiliary proteins and post-translational modification

Autor: Parisa Asghari, David RL Scriven, Myles Ng, Pankaj Panwar, Keng C Chou, Filip van Petegem, Edwin DW Moore

Publikováno v: eLife, Vol 9 (2020)

The effects of the immunophilins, FKBP12 and FKBP12.6, and phosphorylation on type II ryanodine receptor (RyR2) arrangement and function were examined using correlation microscopy (line scan confocal imaging of Ca2+ sparks and dual-tilt electron tomo

Externí odkaz: https://doaj.org/article/da3ac013f2e848feb2dbf8e6e0317711

Using hiPSC-CMs to Examine Mechanisms of Catecholaminergic Polymorphic Ventricular Tachycardia

Autor: Alia Arslanova, Sanam Shafaattalab, Kevin Ye, Parisa Asghari, Lisa Lin, BaRun Kim, Thomas M. Roston, Leif Hove‐Madsen, Filip Van Petegem, Shubhayan Sanatani, Edwin Moore, Francis Lynn, Mads Søndergaard, Yonglun Luo, S. R. Wayne Chen, Glen F. Tibbits

Publikováno v: Arslanova, A, Shafaattalab, S, Ye, K, Asghari, P, Lin, L, Kim, B R, Roston, T M, Hove-Madsen, L, Van Petegem, F, Sanatani, S, Moore, E, Lynn, F, Søndergaard, M, Luo, Y, Chen, S R W & Tibbits, G F 2021, ' Using hiPSC-CMs to Examine Mechanisms of Catecholaminergic Polymorphic Ventricular Tachycardia ', Current Protocols, vol. 1, no. 12, e320 . https://doi.org/10.1002/cpz1.320
Arslanova, A, Shafaattalab, S, Ye, K, Asghari, P, Lin, L, Kim, B, Roston, T M, Hove-Madsen, L, Van Petegem, F, Sanatani, S, Moore, E, Lynn, F, Søndergaard, M, Luo, Y, Chen, S R W & Tibbits, G F 2021, ' Using hiPSC-CMs to Examine Mechanisms of Catecholaminergic Polymorphic Ventricular Tachycardia ', Current Protocols, vol. 1, no. 12, pp. e320 . https://doi.org/10.1002/cpz1.320

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a potentially lethal inherited cardiac arrhythmia condition, triggered by physical or acute emotional stress, that predominantly expresses early in life. Gain-of-function mutations in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41fbbc80217c59e32b24780270fdb16e
https://pure.au.dk/portal/da/publications/using-hipsccms-to-examine-mechanisms-of-catecholaminergic-polymorphic-ventricular-tachycardia(f63258be-de72-40d2-8d0e-cf2459339798).html

Author response: Cardiac ryanodine receptor distribution is dynamic and changed by auxiliary proteins and post-translational modification

Autor: Filip Van Petegem, Parisa Asghari, Edwin D.W. Moore, Keng C. Chou, Myles Ng, Pankaj Panwar, David R.L. Scriven

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::59ef9830aaca796de24606a7e8583521
https://doi.org/10.7554/elife.51602.sa2

Artificial intelligence based ensemble modeling of wastewater treatment plant using jittered data

Autor: Parisa Asghari, Elnaz Sharghi, Vahid Nourani

Publikováno v: Journal of Cleaner Production. 291:125772

In this study, black box artificial intelligence models (AI) including feed forward neural network (FFNN), support vector regression (SVR) and adaptive neuro-fuzzy inference system (ANFIS) were used to predict effluent biological oxygen demand (BODef

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dedb55d44189257c23b440fa49891369
https://doi.org/10.1016/j.jclepro.2020.125772