Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Parimal Rana"'
Autor:
Yunlu Xue, Sean K Wang, Parimal Rana, Emma R West, Christin M Hong, Helian Feng, David M Wu, Constance L Cepko
Publikováno v:
eLife, Vol 10 (2021)
Retinitis pigmentosa (RP) is an inherited retinal disease affecting >20 million people worldwide. Loss of daylight vision typically occurs due to the dysfunction/loss of cone photoreceptors, the cell type that initiates our color and high-acuity visi
Externí odkaz:
https://doaj.org/article/1d602be0a51c44ae81306f4e01339bb2
Autor:
David M. Wu, Xuke Ji, Maryna V. Ivanchenko, Michelle Chung, Mary Piper, Parimal Rana, Sean K. Wang, Yunlu Xue, Emma West, Sophia R. Zhao, Hongbin Xu, Marcelo Cicconet, Wenjun Xiong, Constance L. Cepko
Publikováno v:
JCI Insight, Vol 6, Iss 2 (2021)
Nrf2, a transcription factor that regulates the response to oxidative stress, has been shown to rescue cone photoreceptors and slow vision loss in mouse models of retinal degeneration (rd). The retinal pigment epithelium (RPE) is damaged in these mod
Externí odkaz:
https://doaj.org/article/66ed3b635a034060a47e1f54e323c711
Publikováno v:
Proceedings of the National Academy of Sciences. 116:10140-10149
Retinitis pigmentosa (RP) is a disease that initially presents as night blindness due to genetic deficits in the rod photoreceptors of the retina. Rods then die, causing dysfunction and death of cone photoreceptors, the cell type that mediates high a
Autor:
Sophia Zhao, Xuke Ji, Parimal Rana, Constance L. Cepko, Michelle Chung, Shuyi Mai, David M. Wu, Yunlu Xue, Wenjun Xiong, Sean K. Wang
Publikováno v:
Proceedings of the National Academy of Sciences. 116:5785-5794
Adeno-associated viral vectors (AAVs) have become popular for gene therapy, given their many advantages, including their reduced inflammatory profile compared with that of other viruses. However, even in areas of immune privilege such as the eye, AAV
Author response: AAV-Txnip prolongs cone survival and vision in mouse models of retinitis pigmentosa
Autor:
Christin M Hong, David M. Wu, Constance L. Cepko, Parimal Rana, Sean K. Wang, Yunlu Xue, Emma R. West, Helian Feng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bd161d6c4c49992d2f318dcd8bff2a6
https://doi.org/10.7554/elife.66240.sa2
https://doi.org/10.7554/elife.66240.sa2
Autor:
Parimal Rana, Sean K. Wang, Constance L. Cepko, Emma R. West, David M. Wu, Helian Feng, Yunlu Xue, Christin M Hong
Retinitis pigmentosa (RP) is an inherited retinal disease, affecting >20 million people worldwide. Loss of daylight vision typically occurs due to the dysfunction/loss of cone photoreceptors, the cell type that initiates our color and high acuity vis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6905731e1ae3f69ba04a8637b06eb5e
https://doi.org/10.1101/2021.01.27.428411
https://doi.org/10.1101/2021.01.27.428411
Autor:
Emma R. West, Parimal Rana, Sean K. Wang, Helian Feng, Constance L. Cepko, David M. Wu, Yunlu Xue, Christin M Hong
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Retinitis pigmentosa (RP) is an inherited retinal disease affecting >20 million people worldwide. Loss of daylight vision typically occurs due to the dysfunction/loss of cone photoreceptors, the cell type that initiates our color and high-acuity visi
Autor:
Parimal Rana, Michelle Chung, Sean K. Wang, Sophia Zhao, Emma R. West, Xuke Ji, Constance L. Cepko, Yunlu Xue, Hongbin Xu, Wenjun Xiong, Mary E. Piper, Maryna V. Ivanchenko, Marcelo Cicconet, David M. Wu
Publikováno v:
JCI Insight, Vol 6, Iss 2 (2021)
JCI Insight
JCI Insight
Nrf2, a transcription factor that regulates the response to oxidative stress, has been shown to rescue cone photoreceptors and slow vision loss in mouse models of retinal degeneration (rd). The retinal pigment epithelium (RPE) is damaged in these mod
Autor:
Wenjun, Xiong, David M, Wu, Yunlu, Xue, Sean K, Wang, Michelle J, Chung, Xuke, Ji, Parimal, Rana, Sophia R, Zhao, Shuyi, Mai, Constance L, Cepko
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Adeno-associated viral (AAV) gene therapy is becoming an important therapeutic modality, especially for ocular diseases, due to its efficiency of gene delivery and relative lack of pathogenicity. However, AAV sometimes can cause inflamma