SIRIUS, Ultra-Scintillating Upconversion Breast Implant for Remote Orthotopic Photodynamic Therapy.

Autor: Kamarudin JBM; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, S117597., Sun B; Department of Biomedical Engineering, College of Design & Engineering, National University of Singapore, Singapore, S117575., Foo ASC; Division of Neurosurgery, Department of Surgery, National University Hospital, National University Health System, Singapore, S119074., Lim XY; MBBS Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, S117597., Judd H; Ngee Ann Polytechnic, Singapore, S599489., Tan X; Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, S117597., Tan XH; Department of Biomedical Engineering, College of Design & Engineering, National University of Singapore, Singapore, S117575., Razar RBBA; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, S117597., Liu M; Department of Biomedical Engineering, College of Design & Engineering, National University of Singapore, Singapore, S117575., Zhong J; Department of Biomedical Engineering, College of Design & Engineering, National University of Singapore, Singapore, S117575., Chua JJE; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, S117597.; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore, S138673.; Neurobiology Program, Life Science Institute, National University of Singapore, Singapore, S117456., Ng CWQ; Division of General Surgery (Breast Surgery), Department of Surgery, National University Hospital, National University Health System, Singapore, S119074., Goh JCH; Department of Biomedical Engineering, College of Design & Engineering, National University of Singapore, Singapore, S117575., Tan TZ; Genomics and Data Analytics Core, Cancer Science Institute of Singapore, National University of Singapore, Singapore, S117599., Parikh BH; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore, S138673., Su X; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore, S138673.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, S117597., Kumar AP; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, S117597.; NUS Center for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, S117597., Ong WY; Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, S117597.; Neurobiology Program, Life Science Institute, National University of Singapore, Singapore, S117456., Yamaguchi N; Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, 153-8904, Japan., Set SY; Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, 153-8904, Japan., Yip GW; Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, S117597., Zhang Y; Department of Biomedical Engineering, College of Design & Engineering, National University of Singapore, Singapore, S117575., Teh DBL; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, S117597.; Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, S117597.; Neurobiology Program, Life Science Institute, National University of Singapore, Singapore, S117456.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, S117597.

Publikováno v: ACS nano [ACS Nano] 2023 Jun 27; Vol. 17 (12), pp. 11593-11606. Date of Electronic Publication: 2023 Jun 12.

Dysfunctional Autophagy, Proteostasis, and Mitochondria as a Prelude to Age-Related Macular Degeneration.

Autor: Lenin RR; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), 1E Kent Ridge Road, NUHS Tower Block Level 7, Singapore 119228, Singapore.; Department of Medical Research, SRM Institute of Science and Technology, Kattankulathur 603203, Tamil Nadu, India., Koh YH; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), 1E Kent Ridge Road, NUHS Tower Block Level 7, Singapore 119228, Singapore., Zhang Z; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), 1E Kent Ridge Road, NUHS Tower Block Level 7, Singapore 119228, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University (NTU), 11 Mandalay Road, Experimental Medicine Building, Singapore 308232, Singapore., Yeo YZ; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology, and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore 138673, Singapore., Parikh BH; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology, and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore 138673, Singapore., Seah I; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), 1E Kent Ridge Road, NUHS Tower Block Level 7, Singapore 119228, Singapore., Wong W; Department of Ophthalmology, National University Hospital (NUH), 1E Kent Ridge Road, NUHS Tower Block Level 7, Singapore 119228, Singapore., Su X; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), 1E Kent Ridge Road, NUHS Tower Block Level 7, Singapore 119228, Singapore.; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology, and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore 138673, Singapore.; Department of Ophthalmology, National University Hospital (NUH), 1E Kent Ridge Road, NUHS Tower Block Level 7, Singapore 119228, Singapore.; Singapore Eye Research Institute (SERI), The Academia, 20 College Road, Level 6 Discovery Tower, Singapore 169856, Singapore.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 May 15; Vol. 24 (10). Date of Electronic Publication: 2023 May 15.

Customized strategies for high-yield purification of retinal pigment epithelial cells differentiated from different stem cell sources.

Autor: Regha K; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, 138673, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, 117597, Singapore., Bhargava M; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, 138673, Singapore.; Department of Ophthalmology, National University Hospital (NUH), Singapore, 119074, Singapore., Al-Mubaarak A; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, 138673, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, 117597, Singapore., Chai C; Lee Kong Chian School of Medicine, Nanyang Technological University (NTU), Singapore, 308232, Singapore., Parikh BH; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, 138673, Singapore., Liu Z; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, 138673, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, 117597, Singapore.; Singapore Eye Research Institute (SERI), Singapore, 169856, Singapore., Wong CSW; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, 138673, Singapore., Hunziker W; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, 138673, Singapore.; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, 117593, Singapore., Lim KL; Lee Kong Chian School of Medicine, Nanyang Technological University (NTU), Singapore, 308232, Singapore., Su X; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, 138673, Singapore. xysu@imcb.a-star.edu.sg.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, 117597, Singapore. xysu@imcb.a-star.edu.sg.; Department of Ophthalmology, National University Hospital (NUH), Singapore, 119074, Singapore. xysu@imcb.a-star.edu.sg.; Singapore Eye Research Institute (SERI), Singapore, 169856, Singapore. xysu@imcb.a-star.edu.sg.

Publikováno v: Scientific reports [Sci Rep] 2022 Sep 16; Vol. 12 (1), pp. 15563. Date of Electronic Publication: 2022 Sep 16.

A bio-functional polymer that prevents retinal scarring through modulation of NRF2 signalling pathway.

Autor: Parikh BH; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Liu Z; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Singapore Eye Research Institute (SERI), Singapore, Singapore., Blakeley P; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Lin Q; Institute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Singh M; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Ong JY; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Ho KH; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Lai JW; Science, Mathematics and Technology Cluster, Singapore University of Technology and Design (SUTD), Singapore, Singapore., Bogireddi H; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Tran KC; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Lim JYC; Institute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Department of Materials Science and Engineering, National University of Singapore, Singapore, Singapore., Xue K; Institute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Al-Mubaarak A; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Yang B; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., R S; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Regha K; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Wong DSL; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Tan QSW; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Zhang Z; Institute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Jeyasekharan AD; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Barathi VA; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Singapore Eye Research Institute (SERI), Singapore, Singapore.; Academic Clinical Program in Ophthalmology, Duke-NUS Medical School, Singapore, Singapore., Yu W; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Cheong KH; Science, Mathematics and Technology Cluster, Singapore University of Technology and Design (SUTD), Singapore, Singapore., Blenkinsop TA; Department of Cellular, Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Hunziker W; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Lingam G; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Singapore Eye Research Institute (SERI), Singapore, Singapore.; Department of Ophthalmology, National University Hospital, Singapore, Singapore., Loh XJ; Institute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore. lohxj@imre.a-star.edu.sg.; Department of Materials Science and Engineering, National University of Singapore, Singapore, Singapore. lohxj@imre.a-star.edu.sg., Su X; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore. xysu@imcb.a-star.edu.sg.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. xysu@imcb.a-star.edu.sg.; Singapore Eye Research Institute (SERI), Singapore, Singapore. xysu@imcb.a-star.edu.sg.; Department of Ophthalmology, National University Hospital, Singapore, Singapore. xysu@imcb.a-star.edu.sg.

Publikováno v: Nature communications [Nat Commun] 2022 May 19; Vol. 13 (1), pp. 2796. Date of Electronic Publication: 2022 May 19.

The Translational Application of Hydrogel for Organoid Technology: Challenges and Future Perspectives.

Autor: Ma P; Fujian Provincial Key Laboratory of Innovative Drug Target Research and State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Xiamen University, Xiamen, 361102, China., Chen Y; Fujian Provincial Key Laboratory of Innovative Drug Target Research and State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Xiamen University, Xiamen, 361102, China., Lai X; Fujian Provincial Key Laboratory of Innovative Drug Target Research and State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Xiamen University, Xiamen, 361102, China., Zheng J; Institute of Materials Research and Engineering, A*STAR (Agency for Science, Technology and Research), 2 Fusionopolis Way, Innovis, #08-03, Singapore, 138634, Singapore., Ye E; Institute of Materials Research and Engineering, A*STAR (Agency for Science, Technology and Research), 2 Fusionopolis Way, Innovis, #08-03, Singapore, 138634, Singapore., Loh XJ; Institute of Materials Research and Engineering, A*STAR (Agency for Science, Technology and Research), 2 Fusionopolis Way, Innovis, #08-03, Singapore, 138634, Singapore., Zhao Y; BayRay Innovation Center, Shenzhen Bay Laboratory (SZBL), Shenzhen, 518132, China., Parikh BH; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 61 Biopolis, Drive, Proteos, Singapore, 138673, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, 10 Medical Dr, Singapore, 117597, Singapore., Su X; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 61 Biopolis, Drive, Proteos, Singapore, 138673, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, 10 Medical Dr, Singapore, 117597, Singapore.; Singapore Eye Research Institute (SERI), The Academia, 20 College Road Discovery Tower Level 6, Singapore, 169856, Singapore.; Department of Ophthalmology, National University Hospital, Singapore, 119074, Singapore., You M; Hangzhou Cancer Institute, Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang Province, Affiliated Hangzhou Cancer Hospital, Zhejiang University School of Medicine, Hangzhou, 310002, China., Wu YL; Fujian Provincial Key Laboratory of Innovative Drug Target Research and State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Xiamen University, Xiamen, 361102, China., Li Z; Institute of Materials Research and Engineering, A*STAR (Agency for Science, Technology and Research), 2 Fusionopolis Way, Innovis, #08-03, Singapore, 138634, Singapore.; Department of Materials Science and Engineering, National University of Singapore, Singapore, 117574, Singapore.

Publikováno v: Macromolecular bioscience [Macromol Biosci] 2021 Oct; Vol. 21 (10), pp. e2100191. Date of Electronic Publication: 2021 Jul 14.