PET imaging of microglia in Alzheimer's disease using copper-64 labeled TREM2 antibodies.

Autor: Shojaei M; Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany., Schaefer R; Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany., Schlepckow K; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany., Kunze LH; Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany., Struebing FL; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Center for Neuropathology and Prion Research, University Hospital, LMU Munich, Munich, Germany., Brunner B; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany., Willem M; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany., Bartos LM; Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany., Feiten A; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Metabolic Biochemistry, Biomedical Center (BMC), Faculty of Medicine, LMU Munich, Munich, Germany., Palumbo G; Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany., Arzberger T; Center for Neuropathology and Prion Research, University Hospital, LMU Munich, Munich, Germany.; Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany., Bartenstein P; Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany.; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany., Parico GC; Denali Therapeutics Inc, South San Francisco, CA, USA., Xia D; Denali Therapeutics Inc, South San Francisco, CA, USA., Monroe KM; Denali Therapeutics Inc, South San Francisco, CA, USA., Haass C; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Metabolic Biochemistry, Biomedical Center (BMC), Faculty of Medicine, LMU Munich, Munich, Germany.; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany., Brendel M; Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany.; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany., Lindner S; Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany.

Publikováno v: Theranostics [Theranostics] 2024 Sep 30; Vol. 14 (16), pp. 6319-6336. Date of Electronic Publication: 2024 Sep 30 (Print Publication: 2024).